(Q35028565)

English

Inverse agonist abolishes desensitization of a constitutively active mutant of thyrotropin-releasing hormone receptor: role of cellular calcium and protein kinase C.

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Europe PubMed Central

PubMed publication ID

5 August 2017

Inverse agonist abolishes desensitization of a constitutively active mutant of thyrotropin-releasing hormone receptor: role of cellular calcium and protein kinase C. (English)

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

desensitization

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based on heuristic

inferred from title

author name string

H Grimberg

1

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

I Zaltsman

2

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

M Lupu-Meiri

3

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

M C Gershengorn

4

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Y Oron

5

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

language of work or name

0 references

publication date

1 March 1999

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

British Journal of Pharmacology

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

126

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

5

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

1097-1106

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Constitutive activity of native thyrotropin-releasing hormone receptors revealed using a protein kinase C-responsive reporter gene

1 reference

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G protein-coupled receptors: heterologous regulation of homologous desensitization and its implications.

1 reference

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Changes in the carboxyl-terminal domain of metabotropic glutamate receptor 1 by alternative splicing generate receptors with differing agonist-independent activity.

1 reference

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delta Opioid receptor in neuronal cells undergoes acute and homologous desensitization

1 reference

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A constitutively active mutant thyrotropin-releasing hormone receptor is chronically down-regulated in pituitary cells: evidence using chlordiazepoxide as a negative antagonist

1 reference

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5-Hydroxytryptamine2A (5-HT2A) receptor desensitization can occur without down-regulation

1 reference

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Somatic mutations in the thyrotropin receptor gene cause hyperfunctioning thyroid adenomas

1 reference

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Constitutively active mutants of the alpha 2-adrenergic receptor

1 reference

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A mutation-induced activated state of the beta 2-adrenergic receptor. Extending the ternary complex model

1 reference

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Negative antagonists promote an inactive conformation of the beta 2-adrenergic receptor

1 reference

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Truncation of the thyrotropin-releasing hormone receptor carboxyl tail causes constitutive activity and leads to impaired responsiveness in Xenopus oocytes and AtT20 cells

1 reference

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Effects of protein kinase C activators upon the late stages of the ACTH secretory pathway of AtT-20 cells

1 reference

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Protein kinases that phosphorylate activated G protein-coupled receptors.

1 reference

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A constitutively activating mutation of the luteinizing hormone receptor in familial male precocious puberty

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Involvement of multiple protein kinase C isozymes in the ACTH secretory pathway of AtT-20 cells

1 reference

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Regulation of Human Interleukin-8 Receptor A: Identification of a Phosphorylation Site Involved in Modulating Receptor Functions

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The role of the calpain-calpastatin system in thyrotropin-releasing hormone-induced selective down-regulation of a protein kinase C isozyme, nPKC epsilon, in rat pituitary GH4C1 cells

1 reference

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Phorbol ester activation of protein kinase C inhibits CNP-stimulated cyclic GMP production in the mouse AtT-20 pituitary tumour cell line

1 reference

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High agonist-independent activity is a distinguishing feature of the dopamine D1B receptor subtype

1 reference

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Synthetic TRF (thyrotropin releasing factor) analogues. II. pGlu-N3imMe-His-Pro-NH2: a synthetic analogue with specific activity greater than that of TRF2.

1 reference

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A new generation of Ca2+ indicators with greatly improved fluorescence properties

1 reference

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8 July 2018

Evidence for tight coupling of receptor occupancy by thyrotropin-releasing hormone to phospholipase C-mediated phosphoinositide hydrolysis in rat pituitary cells: use of chlordiazepoxide as a competitive antagonist

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565886

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Mechanism of membrane electrical response to thyrotropin-releasing hormone in Xenopus oocytes injected with GH3 pituitary cell messenger ribonucleic acid

1 reference

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Use of receptor antagonist in elucidating the mechanism of action of TRH in GH3 cells

1 reference

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Palmitoylation of the human beta 2-adrenergic receptor. Mutation of Cys341 in the carboxyl tail leads to an uncoupled nonpalmitoylated form of the receptor

1 reference

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Expression cloning of a cDNA encoding the mouse pituitary thyrotropin-releasing hormone receptor

1 reference

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Activation of two different receptors mobilizes calcium from distinct stores in Xenopus oocytes

1 reference

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Extracellular calcium participates in responses to acetylcholine in Xenopus oocytes.

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Truncation of the extended carboxyl-terminal domain increases the expression and regulatory activity of the avian beta-adrenergic receptor

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Homologous and heterologous acute desensitization of vasopressin V1a receptor in Xenopus oocytes

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Calcium entry in Xenopus oocytes: effects of inositol trisphosphate, thapsigargin and DMSO.

1 reference

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Desensitization of the response to thyrotropin-releasing hormone in Xenopus oocytes is an amplified process that precedes calcium mobilization

1 reference

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Contribution of response kinetics to the response pattern: studies of responses to thyrotropin-releasing hormone in Xenopus oocytes

1 reference

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Protein kinase C involvement in homologous desensitization of delta-opioid receptor coupled to Gi1-phospholipase C activation in Xenopus oocytes

1 reference

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Thyrotropin-releasing hormone stimulation of phosphoinositide hydrolysis desensitizes. Evidence against mediation by protein kinase C or calcium

1 reference

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based on heuristic

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Protein kinase C modulation of cardiomyocyte angiotensin II and vasopressin receptor desensitization

1 reference

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Dual regulation by protein kinase C of the muscarinic response in Xenopus oocytes

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Turned on to ill effect

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Identifiers

10.1038/SJ.BJP.0702415

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

ResearchGate publication ID

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