(Q35033125)

5 August 2017

Checkpoint kinase 1 (Chk1) is required for mitotic progression through negative regulation of polo-like kinase 1 (Plk1) (English)

1 reference

5 August 2017

Jiabin Tang

1

1 reference

5 August 2017

Raymond L Erikson

series ordinal

2

1 reference

5 August 2017

Xiaoqi Liu

series ordinal

3

1 reference

5 August 2017

language of work or name

English

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publication date

27 July 2006

1 reference

Proceedings of the National Academy of Sciences of the United States of America

5 August 2017

1 reference

5 August 2017

103

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5 August 2017

11964-11969

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5 August 2017

32

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The spindle checkpoint: tension versus attachment.

5 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1567681

Inhibition of human Chk1 causes increased initiation of DNA replication, phosphorylation of ATR targets, and DNA breakage

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1567681

Centrosome-associated Chk1 prevents premature activation of cyclin-B-Cdk1 kinase

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1567681

Chk1 in the DNA damage response: conserved roles from yeasts to mammals

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1567681

Chk1 is haploinsufficient for multiple functions critical to tumor suppression

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1567681

Wee1-dependent mechanisms required for coordination of cell growth and cell division

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1567681

Chk1 Kinase Negatively Regulates Mitotic Function of Cdc25A Phosphatase through 14-3-3 Binding

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1567681

Chk1-deficient tumour cells are viable but exhibit multiple checkpoint and survival defects

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1567681

Disruption of the checkpoint kinase 1/cell division cycle 25A pathway abrogates ionizing radiation-induced S and G2 checkpoints

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1567681

Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1567681

Aberrant cell cycle checkpoint function and early embryonic death in Chk1(-/-) mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1567681

The human homologs of checkpoint kinases Chk1 and Cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1567681

Targeting polo-like kinase 1 for cancer therapy.

8 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0604987103

Inhibition of Polo-like kinase-1 by DNA damage occurs in an ATM- or ATR-dependent fashion.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0604987103

Human Chk1 expression is dispensable for somatic cell death and critical for sustaining G2 DNA damage checkpoint.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1567681

Polo-like kinase-1 is a target of the DNA damage checkpoint

25 October 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0604987103

21 January 2018

Identifiers

DOI

10.1073/PNAS.0604987103

1 reference

5 August 2017

0 references

1 reference

5 August 2017

1 reference