(Q35035615)

5 August 2017

Mechanism of toxicity of nitro compounds used in the chemotherapy of trichomoniasis (English)

1 reference

5 August 2017

1 reference

1 reference

Moreno SN

1

1 reference

PubMed ID

3830698

5 August 2017

Docampo R

series ordinal

2

1 reference

PubMed ID

3830698

5 August 2017

language of work or name

1 reference

1 December 1985

1 reference

5 August 2017

10

1 reference

Environmental Health Perspectives

inferred from page(s)

published in

1 reference

5 August 2017

64

1 reference

5 August 2017

199-208

1 reference

Metronidazole: proven benefits and potential risks.

5 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568619

Inhibition of plant fatty acid synthesis by nitroimidazoles

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568619

Intestinal and urogenital flagellates.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568619

A metronidazole metabolite in human urine and its risk

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568619

The action of metronidazole on anaerobic bacilli and similar organisms.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568619

Interaction of nitroimidazole drugs with DNA in vitro: structure-activity relationships

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568619

Cellular electron transfer and radical mechanisms for drug metabolism

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568619

Urologic aspects of trichomoniasis.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568619

Action of clinically utilized 5-nitroimidazoles on microorganisms

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568619

Chemosensitization by lipophilic nitroimidazoles

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568619

Mutagenicity of nitrofuran derivatives: Review

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568619

Metronidazole metabolism in cultures of Entamoeba histolytica and Trichomonas vaginalis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568619

Tritrichomonas foetus: ultrastructural localization of basic proteins and carbohydrates.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568619

Nifuratel (Magmilor) in trichomonal vaginitis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568619

Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein)

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568619

Nitrofurantoin in the treatment of vaginal trichomoniasis in women

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568619

The epidemiology of trichomoniasis and the role of this infection in the development of carcinoma of the cervix

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568619

The mutagenic action of nitroimidazoles. I. Metronidazole, nimorazole, dimetridazole and ronidazole.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568619

Superoxide dismutase in the anaerobic flagellates, Tritrichomonas foetus and Monocercomonas sp.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568619

Reduction of nitroimidazole derivatives by hydrogenosomal extracts of Trichomonas vaginalis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568619

Metronidazole radical anion generation in vivo in Trichomonas vaginalis: oxygen quenching is enhanced in a drug-resistant strain

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568619

The Fate of Metronidazole and its Implications in Chemotherapy

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568619

Mutagenicity of metronidazole: Activation by mammalian liver microsomes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568619

Uptake of Metronidazole and Its Effect on Viability in Trichomonads and Entamoeba invadens Under Anaerobic and Aerobic Conditions

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568619

Antitrichomonad action, mutagenicity, and reduction of metronidazole and other nitroimidazoles

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568619

Biliary and renal excretion, hepatic metabolism, and hepatic subcellular distribution of metronidazole in the rat

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568619

Metronidazole: view of uses and toxicity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568619

Acetylcholine-like activity in sciatic nerve—A re-evaluation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568619

The anaerobic metabolism of metronidazole forms N-(2-hydroxyethyl)-oxamic acid

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568619

The mutagenic action of nitroimidazoles. IV. A comparison of the mutagenic action of several nitroimidazoles and some imidazoles

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568619

Radiosensitization, Mutagenicity, and Toxicity of Escherichia coli by Several Nitrofurans and Nitroimidazoles

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568619

Screening for the mutagenicity of nitro-group containing hypoxic cell radiosensitizers using Salmonella typhimurium strains TA 100 and TA98.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568619

Chemotherapy of parasitic infections

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568619

Tinidazole (TNZ) (ethyl[2-(2-methyl-5-nitro-1-imidazolyl) ethyl]sulphone) is mutagenic in a Salmonella typhimurium assay

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568619

The use of nitroaromatic compounds as hypoxic cell radiosensitizers

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568619

The contribution of metronidazole and two metabolites to the mutagenic activity detected in urine of treated humans and mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568619

Structure-activity relationships in the development of hypoxic cell radiosensitizers. II. Cytotoxicity and therapeutic ratio

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568619

Metronidazole and tinidazole in a single large dose for treating urogenital infections with Trichomonas vaginalis in men

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568619

Trichomoniasis, candidiasis, and Corynebacterium vaginale vaginitis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568619

The “Other” Veneral Diseases: Herpes Simplex, Trichomoniasis and Candidiasis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568619

Acetamide—a metabolite of metronidazole formed by the intestinal flora

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568619

The role of catalytic superoxide formation in the O2 inhibition of nitroreductase

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568619

Mutagenicity and mutagenic specificity of metronidazole and niridazole in Neurospora crassa

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568619

Trichomonas Vaginalis cervicitis and its relationship to cervical cancer.A histocytological study

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568619

Trichomonas vaginalis infection in the male.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568619

Drug metabolism and chemosensitization. Nitroimidazoles as inhibitors of drug metabolism.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568619

The mode of action of metronidazole against Trichomonas vaginalis.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1568619

The reductive metabolism of metronidazole and ronidazole by aerobic liver microsomes

25 October 2018

1 reference

12 December 2020

Generation of free radicals from metronidazole and other nitroimidazoles by Tritrichomonas foetus

1 reference

12 December 2020

Drug residue formation from ronidazole, a 5-nitroimidazole. II. Involvement of microsomal NADPH-cytochrome P-450 reductase in protein alkylation in vitro

1 reference

12 December 2020

Modification of guanine derivatives by reduced 2-nitroimidazoles

1 reference

12 December 2020

Trichomoniasis. New ideas on an old disease

1 reference

12 December 2020

Drug residue formation from ronidazole, a 5-nitroimidazole. VI. Lack of mutagenic activity of reduced metabolites and derivatives of ronidazole

1 reference

12 December 2020

Interaction of metronidazole with nucleic acids in vitro

1 reference

12 December 2020

Structure-cytotoxicity relationships of nitroimidazoles in an in vitro system

1 reference

12 December 2020

Toxicity of nitro compounds toward hypoxic mammalian cells in vitro: dependence on reduction potential

1 reference

12 December 2020

Metabolites from the reduction of metronidazole by xanthine oxidase

1 reference

12 December 2020

The mode of action of metronidazole in Trichomonas vaginalis and other micro-organisms

1 reference

12 December 2020

Anaerobic reduction of nitroimidazoles by reduced flavin mononucleotide and by xanthine oxidase

1 reference

12 December 2020

The activity of nitro-compounds against Bacteroides fragilis is related to their electron affinity

1 reference

12 December 2020

In vivo potentiation of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea by the radiation sensitizer benznidazole

1 reference

12 December 2020

Fine structure and cytochemistry of the hydrogenosome of Tritrichomonas foetus

1 reference

12 December 2020

No detectable reaction of the anion radical metabolite of nitrofurans with reduced glutathione or macro-molecules

1 reference

12 December 2020

Redox processes in radiation biology and cancer

1 reference

12 December 2020

Distinct reduction of nitrofurans and metronidazole to free radical metabolites by Tritrichomonas foetus hydrogenosomal and cytosolic enzymes

1 reference

12 December 2020

Drug residue formation from ronidazole, a 5-nitroimidazole. I. Characterization of in vitro protein alkylation

1 reference

12 December 2020

Effect of metronidazole on hydrogen production by Clostridium acetobutylicum

1 reference

12 December 2020

Radiosensitizers of hypoxic cells in solid tumors

1 reference

12 December 2020

[The activity of 1-(2-hydroxyethyl)-2-methyl-5-nitroimidazole (R. P. 8823) against experimental Trichomonas vaginalis infections]

1 reference

12 December 2020

The production of nitrite from radiolytic, photolytic and electrolytic degradation of metronidazole

1 reference

12 December 2020

Drug residue formation from ronidazole, a 5-nitroimidazole. III. Studies on the mechanism of protein alkylation in vitro

1 reference

12 December 2020

Studies on the trichomonacidal effects of various nitrofuran preparations

1 reference

12 December 2020

Reductive fragmentation of 2-nitroimidazoles in the presence of nitroreductases--glyoxal formation from misonidazole

1 reference

12 December 2020

An iron-containing superoxide dismutase in Tritrichomonas foetus

1 reference

12 December 2020

Base specific interaction of reductively activated nitroimidazoles with DNA

1 reference

12 December 2020

Hydrogenosomal ferredoxin of the anaerobic protozoon, Tritrichomonas foetus

1 reference

12 December 2020

1 reference

12 December 2020

Studies on the action of nitroimidazole drugs. The products of nitroimidazole reduction

1 reference

12 December 2020

Drug residue formation from ronidazole, a 5-nitroimidazole. V. Cysteine adducts formed upon reduction of ronidazole by dithionite or rat liver enzymes in the presence of cysteine

1 reference

12 December 2020

Isolation of Trichomonas vaginalis from the respiratory tract of infants with respiratory disease

1 reference

12 December 2020

Identifiers

DOI

10.1289/EHP.8564199

1 reference

5 August 2017

1 reference

5 August 2017

1 reference

PubMed ID

3830698