(Q35037092)

5 August 2017

title

Some historical aspects of N-aryl carcinogens and their metabolic activation (English)

1 reference

5 August 2017

J. A. Miller

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6339227

2 October 2023

E. C. Miller

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6339227

2 October 2023

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=6339227

2 October 2023

publication date

1 March 1983

1 reference

full work available at URL

5 August 2017

https://doi.org/10.1289/ehp.83493

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6339227

https://europepmc.org/articles/PMC1569122

2 October 2023

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6339227

https://europepmc.org/articles/PMC1569122?pdf=render

2 October 2023

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6339227

https://ehp.niehs.nih.gov/doi/pdf/10.1289/ehp.83493

2 October 2023

1 reference

https://api.crossref.org/works/10.1289/EHP.83493

Environmental Health Perspectives

2 October 2023

published in

1 reference

5 August 2017

volume

49

1 reference

5 August 2017

page(s)

3-12

1 reference

EVIDENCE FOR THE BINDING OF POLYNUCLEAR AROMATIC HYDROCARBONS TO THE NUCLEIC ACIDS OF MOUSE SKIN: RELATION BETWEEN CARCINOGENIC POWER OF HYDROCARBONS AND THEIR BINDING TO DEOXYRIBONUCLEIC ACID.

5 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569122

Chemical carcinogens and their modes of action

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569122

A working hypothesis for the mode of carcinogenesis of aromatic amines

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569122

The carcinogenic aminoazo dyes.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569122

Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569122

The role of gene dosage and genetic transpositions in carcinogenesis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569122

INteractions between carcinogens and proteins

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569122

The origin of human cancers

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569122

8-(N-2-Fluorenylacetamido) guanosine, an Arylamidation Reaction Product of Guanosine and the Carcinogen N-Acetoxy-N-2-fluorenylacetamide in Neutral Solution*

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569122

N-hydroxy-2-acetylaminofluorene sulfotransferase: its probable role in carcinogenesis and in protein-(methion-S-yl) binding in rat liver

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569122

On the mechanism of action of carcinogenic aromatic amines. I. Binding of 2-acetylaminofluorene and N-hydroxy-2-acetylaminofluorene to rat-liver nucleic acids in vivo.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569122

N-acetoxy-N-acetylaminoarenes and nitrosoarenes one-electron non-enzymatic and enzymatic oxidation products of various carcinogenic aromatic acethydroxamic acids

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569122

3-methylmercapto-N-methyl-4-aminoazobenzene: an alkaline-degradation product of a labile protein-bound dye in the livers of rats fed N,N-dimethyl-4-aminoazobenzene

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569122

Carcinogenesis by chemicals: an overview--G. H. A. Clowes memorial lecture

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569122

The Metabolic Activation of Carcinogenic Aromatic Amines and Amides1

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569122

Formation of electrophilic N-acetoxyarylamines in cytosoles from rat mammary gland and other tissues by transacetylation from the carcinogen N-hydroxy-4-acetylaminobiphenyl

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569122

Electrophilic N-acetoxyaminoarenes derived from carcinogenic N-hydroxy-N-acetylaminoarenes by enzymatic deacetylation and transacetylation in liver☆

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569122

Radical accumulation in liver microsomal membranes during biotransformation of aromatic amines and nitro compounds.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569122

Enzymatic activation of the carcinogen 4-hydroxyaminoquinoline-1-oxide and its interaction with cellular macromolecules.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569122

The covalent binding of metabolites of tritiated 2-methyl-4-dimethylamino-azobenzene to rat liver nucleic acids and proteins, and the carcinogenicity of the unlabelled compound in partially hepatectomised rats.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569122

Carcinogens are mutagens: a simple test system combining liver homogenates for activation and bacteria for detection

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569122

Structures of hepatic nucleic acid-bound dyes in rats given the carcinogen N-methyl-4-aminoazobenzene

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569122

N-substitution of carbon 8 in guanosine and deoxyguanosine by the carcinogen N-benzoyloxy-N-methyl-4-aminoazobenzene in vitro

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569122

Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569122

Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals: discussion

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569122

Quantitative analysis of N-(guanin-8-yl)-N-acetyl-2-aminofluorene and N-(guanin-8-yl)-2-aminofluorene in modified DNA by hydrolysis in trifluoroacetic acid and high pressure liquid chromatography

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569122

Seryl-tRNA synthetase and activation of the carcinogen 4-nitroquinoline 1-oxide

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569122

Promotion by dietary phenobarbital of hepatocarcinogenesis by 2-methyl-N,N-dimethyl-4-aminoazobenzene in the rat

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569122

The reaction of mustard gas with nucleic acids in vitro and in vivo

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569122

Studies on ethionine. III. Incorporation of ethionine into rat proteins.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569122

Electrophoretic studies on the soluble proteins from livers of rats fed aminoazo dyes.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569122

Electrophoretic and ultracentrifugal studies on the soluble proteins of various tumors and of livers from rats fed 4-dimethylaminoazobenzene.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569122

Studies on the formation of protein-bound derivatives of 3,4-benzpyrene in the epidermal fraction of mouse skin.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569122

The N- and ringhydroxylation of 2-acetylaminofluorene during carcinogenesis in the rat.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569122

On the protective action of certain polycyclic aromatic hydrocarbons against carcinogenesis by aminoazo dyes and 2-acetylaminofluorene.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569122

Enzymatic deacetylation of N-hydroxy-2-acetylaminofluorene by liver microsomes

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569122

Sulfotransferase Activation of N-Hydroxy-2-acetylaminofluorene in Rodent Livers Susceptible and Resistant to this Carcinogen

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569122

Reactions in vitro of some tissue nucleophiles with the glucuronide of the carcinogen N-hydroxy-2-acetylaminofluorene

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1569122

Identification of the persistently bound form of the carcinogen N-acetyl-2-aminofluorene to rat liver DNA in vivo

25 October 2018

1 reference

12 December 2020

In vivo combinations between carcinogens and tissue constituents and their possible role in carcinogenesis

1 reference

12 December 2020

The biochemistry of cancer of the bladder

1 reference

12 December 2020

THE COMPARATIVE CARCINOGENICITIES OF 2-ACETYLAMINOFLUORENE AND ITS N-HYDROXY METABOLITE IN MICE, HAMSTERS, AND GUINEA PIGS

1 reference

12 December 2020

Biliary excretion of the O-glucuronide of N-hydroxy-2-acetylamino-fluorene by the rat and rabbit

1 reference

12 December 2020

Studies on the structures of polar dyes from liver proteins of rats fed N-methyl-4-aminoazobenzene: I. Retention of the methyl group

1 reference

12 December 2020

Synthesis of the O-glucuronide of N-2-fluorenylhydroxylamine. Reaction with nucleic acids and with guanosine 5'-monophosphate

1 reference

12 December 2020

1 reference

12 December 2020

N-Hydroxy-2-acetylaminofluorene: a metabolite of 2-acetylaminofluorene with increased carcinogenic activity in the rat

1 reference

12 December 2020

N-Benzoyloxy-N-methyl-4-aminoazobenzene: its carcinogenic activity in the rat and its reactions with proteins and nucleic acids and their constituents in vitro

1 reference

12 December 2020

ON THE STRUCTURE OF THE GLUCURONIDE OF N-HYDROXY-2-ACETYLAMINOFLUORENE

1 reference

12 December 2020

Studies on the metabolism of 2-acetylaminofluorene-9-C14

1 reference

12 December 2020

Nucleic acid guanine: reaction with the carcinogen N-acetoxy-2-acetylaminofluorene

1 reference

12 December 2020

Liver tumor inhibition and adrenal histologic responses in rats to which 3'-methyl-4-dimethylaminoazobenzene and 20-methylcholanthrene were simultaneously administered

1 reference

12 December 2020

Studies on structures of polar dyes derived from the liver proteins of rats fed N-methyl-4-aminoazobenzene. 3. Tyrosine and homocysteine sulfoxide polar dyes

1 reference

12 December 2020

[Inhibition of 2-acetylaminofluorene tumors in rats with simultaneously fed 20-methylcholanthrene, 9:10-dimethyl-1:2-benzanthracene and chrysene, and consideration of sex difference in tumor genesis with 2-acetyl-aminoflurene]

1 reference

12 December 2020

On the interaction of N-2-fluorenylhydroxylamine with nucleic acids in, vitro

1 reference

12 December 2020

Studies with mustards. III. In vivo fixation of C14 from nitrogen mustard-C14H3 in nucleic acid fractions of animal tissues

1 reference

12 December 2020

Mutations and decreases in density of transforming DNA produced by derivatives of the carcinogens 2-acetyl-aminofluorene and N-methyl-4-aminoazobenzene

1 reference

12 December 2020

Some aspects of the experimental induction of tumours of the bladder

1 reference

12 December 2020

The carcinogenic action of benzidine

1 reference

12 December 2020

The apparent binding of radioactive 2-acetylaminofluorene to rat-liver ribonucleic acid in vivo

1 reference

12 December 2020

Chemistry, carcinogenicity, and metabolism of 2-fluorenamine and related compounds

1 reference

12 December 2020

N-Hydroxylation: A new metabolic reaction observed in the rat with the carcinogen 2-acetylaminofluorene

1 reference

12 December 2020

Studies on structures of polar dyes derived from the liver proteins of rats fed N-methyl-4-aminoazobenzene. II. Identity of synthetic 3-(homocystein-S-yl)-N-methyl-4-aminoazobenzene with the major polar dye P2b

1 reference

12 December 2020

Reaction of the glucuronide of the carcinogen N-hydroxy-2-acetylaminofluorene with nucleic acids

1 reference

12 December 2020

STUDIES ON THE MOLECULAR MECHANISM OF HYDROCARBON CARCINOGENESIS

1 reference

12 December 2020

Two specific azodye-carcinogen-binding proteins of the rat liver. The identity of amino acid residues which bind the azodye

1 reference

12 December 2020

Enzyme-catalyzed reactions of the carcinogen N-hydroxy-2-fluorenylacetamide with nucleic acid

1 reference

12 December 2020

On the metabolic activation of the carcinogen N-hydroxy-N-2-acetylaminofluorene. 3. Oxidation with horseradish peroxidase to yield 2-nitrosofluorene and N-acetoxy-N-2-acetylaminofluorene

1 reference

12 December 2020

Identifiers

DOI

10.1289/EHP.83493

1 reference

5 August 2017

1 reference

5 August 2017

1 reference