(Q35037424)

5 August 2017

title

Induction of human fetal hemoglobin via the NRF2 antioxidant response signaling pathway (English)

1 reference

5 August 2017

Elizabeth R Macari

1

1 reference

5 August 2017

Christopher H Lowrey

series ordinal

2

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5 August 2017

language of work or name

English

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publication date

4 April 2011

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5 August 2017

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5 August 2017

volume

117

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5 August 2017

issue

22

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5 August 2017

page(s)

5987-5997

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Therapy for beta-globinopathies: a brief review and determinants for successful and safe correction

5 August 2017

cites work

1 reference

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8 July 2018

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8 July 2018

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Nrf2 signaling and cell survival

8 July 2018

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8 July 2018

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Acetylation of Nrf2 by p300/CBP augments promoter-specific DNA binding of Nrf2 during the antioxidant response

8 July 2018

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8 July 2018

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A cell stress signaling model of fetal hemoglobin induction: what doesn't kill red blood cells may make them stronger

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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Resveratrol induces glutathione synthesis by activation of Nrf2 and protects against cigarette smoke-mediated oxidative stress in human lung epithelial cells

8 July 2018

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8 July 2018

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Neither DNA hypomethylation nor changes in the kinetics of erythroid differentiation explain 5-azacytidine's ability to induce human fetal hemoglobin

8 July 2018

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Consequences and costs of noncompliance with iron chelation therapy in patients with transfusion-dependent thalassemia: a literature review.

8 July 2018

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Developmental- and differentiation-specific patterns of human gamma- and beta-globin promoter DNA methylation

8 July 2018

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8 July 2018

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Sickle cell disease: old discoveries, new concepts, and future promise

8 July 2018

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Chemoprotective and carcinogenic effects of tert-butylhydroquinone and its metabolites

8 July 2018

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A functional screen for Krüppel-like factors that regulate the human gamma-globin gene through the CACCC promoter element

8 July 2018

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Differential responses of the Nrf2-Keap1 system to laminar and oscillatory shear stresses in endothelial cells

8 July 2018

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Utility of siRNA against Keap1 as a strategy to stimulate a cancer chemopreventive phenotype

8 July 2018

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A standard curve based method for relative real time PCR data processing

8 July 2018

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Regulation of Nrf2 transactivation domain activity. The differential effects of mitogen-activated protein kinase cascades and synergistic stimulatory effect of Raf and CREB-binding protein

8 July 2018

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Improvements in the HbVar database of human hemoglobin variants and thalassemia mutations for population and sequence variation studies

8 July 2018

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Gene mutations in human haemoglobin: the chemical difference between normal and sickle cell haemoglobin

8 July 2018

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Hydroxyurea induces fetal hemoglobin by the nitric oxide-dependent activation of soluble guanylyl cyclase

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3112042

Nuclear transcription factor GATA-1 is activated during aclacinomycin-induced erythroid differentiation

8 July 2018

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Major hematologic diseases in the developing world- new aspects of diagnosis and management of thalassemia, malarial anemia, and acute leukemia.

8 July 2018

1 reference

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Resveratrol, a natural dietary phytoalexin, possesses similar properties to hydroxyurea towards erythroid differentiation.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3112042

Ablation of Nrf2 function does not increase the erythroid or megakaryocytic cell lineage dysfunction caused by p45 NF-E2 gene disruption

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3112042

An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3112042

Fetal hemoglobin in sickle cell anemia: determinants of response to hydroxyurea. Multicenter Study of Hydroxyurea.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3112042

NRF2, a member of the NFE2 family of transcription factors, is not essential for murine erythropoiesis, growth, and development

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3112042

Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3112042

ARE- and TRE-mediated regulation of gene expression. Response to xenobiotics and antioxidants

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3112042

Human myeloid leukemia cell lines: a review

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3112042

Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3112042

Strides made in red blood cell disorders, but substantial barriers to care remain

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3112042

Accumulation of gamma-globin mRNA in human erythroid cells treated with angelicin

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3112042

Mithramycin induces fetal hemoglobin production in normal and thalassemic human erythroid precursor cells

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3112042

The Cap'n'Collar basic leucine zipper transcription factor Nrf2 (NF-E2 p45-related factor 2) controls both constitutive and inducible expression of intestinal detoxification and glutathione biosynthetic enzymes

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3112042

Mortality in sickle cell disease. Life expectancy and risk factors for early death.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3112042

Long-term results of related myeloablative stem-cell transplantation to cure sickle cell disease

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3112042

Action of Nrf2 and Keap1 in ARE-mediated NQO1 expression by quercetin

9 December 2018

1 reference

12 December 2020

Hemin-induced activation of the thioredoxin gene by Nrf2. A differential regulation of the antioxidant responsive element by a switch of its binding factors

1 reference

12 December 2020

Rapid analysis of hemoglobin variants by cation-exchange HPLC

1 reference

12 December 2020

Pharmacologic treatment of thalassemia intermedia with hydroxyurea

1 reference

12 December 2020

10.1182/BLOOD-2010-10-314096

Identifiers

DOI

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5 August 2017

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5 August 2017

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