(Q35041753)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10602324%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

title

Pharmacological characterization of antagonists of the C5a receptor (English)

1 reference

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2 November 2019

2

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2 November 2019

author name string

N J Paczkowski

1

1 reference

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2 November 2019

J B Whitmore

3

1 reference

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2 November 2019

A J Short

4

1 reference

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2 November 2019

A K Wong

5

1 reference

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2 November 2019

P N Monk

6

1 reference

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2 November 2019

S A Cain

7

1 reference

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2 November 2019

D P Fairlie

8

1 reference

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2 November 2019

S M Taylor

9

1 reference

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2 November 2019

language of work or name

English

0 references

publication date

1 December 1999

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10602324%20AND%20SRC:MED&resulttype=core&format=json

British Journal of Pharmacology

2 November 2019

published in

1 reference

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2 November 2019

volume

128

1 reference

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2 November 2019

issue

7

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2 November 2019

page(s)

1461-1466

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Effects of a new C5a receptor antagonist on C5a- and endotoxin-induced neutropenia in the rat.

2 November 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571783

Expression of receptors for C5a anaphylatoxin (CD88) on human bronchial epithelial cells: enhancement of C5a-mediated release of IL-8 upon exposure to cigarette smoke

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571783

Molecular adjuvant effects of a conformationally biased agonist of human C5a anaphylatoxin.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571783

Expression of the receptor for complement C5a (CD88) is up-regulated on reactive astrocytes, microglia, and endothelial cells in the inflamed human central nervous system.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571783

CD88 antibodies specifically bind to C5aR on dermal CD117+ and CD14+ cells and react with a desmosomal antigen in human skin

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571783

Differential regulation of G-protein-mediated signaling by chemokine receptors

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571783

Human chemotaxis receptor genes cluster at 19q13.3-13.4. Characterization of the human C5a receptor gene

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571783

Site-specific mutagenesis of residues in the human C5a anaphylatoxin which are involved in possible interaction with the C5a receptor

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571783

Two-site binding of C5a by its receptor: an alternative binding paradigm for G protein-coupled receptors

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571783

C5A anaphylatoxin and its seven transmembrane-segment receptor

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571783

The human chemoattractant complement C5a receptor inhibits cyclic AMP accumulation through Gi and Gz proteins

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571783

Cellular expression of the C5a anaphylatoxin receptor (C5aR): demonstration of C5aR on nonmyeloid cells of the liver and lung

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571783

N-formylpeptide and complement C5a receptors are expressed in liver cells and mediate hepatic acute phase gene regulation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571783

Induction of interleukin-8 synthesis from monocytes by human C5a anaphylatoxin

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571783

Complement-mediated arachidonate metabolism

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571783

Effects of the anaphylatoxins on circulation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571783

Identification of receptor-binding residues in the inflammatory complement protein C5a by site-directed mutagenesis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571783

Expression cloning of a receptor for C5a anaphylatoxin on differentiated HL-60 cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571783

The chemotactic receptor for human C5a anaphylatoxin

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571783

Biologic activity of synthetic analogues of C5a anaphylatoxin

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571783

Human C5a anaphylatoxin: gene cloning and expression in Escherichia coli

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571783

Low-molecular-weight peptidic and cyclic antagonists of the receptor for the complement factor C5a.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571783

The influence of Lys68 in decepeptide agonists of C5a on C5a receptor binding, activation and selectivity.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571783

Small molecular probes for G-protein-coupled C5a receptors: conformationally constrained antagonists derived from the C terminus of the human plasma protein C5a.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571783

Biologically active conformer of the effector region of human C5a and modulatory effects of N-terminal receptor binding determinants on activity.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571783

Synthetic C5a receptor agonists. Pharmacology, metabolism and in vivo cardiovascular and hematologic effects.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571783

The amino terminus of the human C5a receptor is required for high affinity C5a binding and for receptor activation by C5a but not C5a analogs

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571783

Reversibility of tachyphylaxis to C5A in guinea pig tissues, perfused human placental lobule, and umbilical artery.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571783

C5a stimulus-secretion coupling in rat basophilic leukaemia (RBL-2H3) cells transfected with the human C5a receptor is mediated by pertussis and cholera toxin-sensitive G proteins

25 October 2018

1 reference

12 December 2020

Development of C5a receptor antagonists. Differential loss of functional responses

1 reference

12 December 2020

Decapeptide agonists of human C5a: the relationship between conformation and spasmogenic and platelet aggregatory activities

1 reference

12 December 2020

Decapeptide agonists of human C5a: the relationship between conformation and neutrophil response

1 reference

12 December 2020

Human C5a and C5a analogs as probes of the neutrophil C5a receptor

1 reference

12 December 2020

Solubilization of the functional C5a receptor from human polymorphonuclear leukocytes

1 reference

12 December 2020

Interaction between the C5a receptor and Gi in both the membrane-bound and detergent-solubilized states

1 reference

12 December 2020

Identification and synthesis of a receptor binding site of human anaphylatoxin C5a

1 reference

12 December 2020

Identification and characterization of the effector region within human C5a responsible for stimulation of IL-6 synthesis

1 reference

12 December 2020

Tryptophan mutants of human C5a anaphylatoxin: a fluorescence anisotropy decay and energy transfer study

1 reference

12 December 2020

Identifiers

DOI

10.1038/SJ.BJP.0702938

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10602324%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10602324%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

1 reference