(Q35043799)

English

Inhibition of interleukin-12 production by auranofin, an anti-rheumatic gold compound, deviates CD4(+) T cells from the Th1 to the Th2 pathway

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Inhibition of interleukin-12 production by auranofin, an anti-rheumatic gold compound, deviates CD4(+) T cells from the Th1 to the Th2 pathway (English)

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

author name string

T S Kim

1

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

B Y Kang

2

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

M H Lee

3

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Y K Choe

4

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

S Y Hwang

5

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

language of work or name

0 references

publication date

1 October 2001

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

British Journal of Pharmacology

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

134

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

3

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

571-578

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Stability and commitment in T helper cell development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572992

8 July 2018

DMARDs in the treatment of rheumatoid arthritis: current agents and future developments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572992

8 July 2018

Signaling and transcription in T helper development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572992

8 July 2018

Retinoid-mediated inhibition of interleukin-12 production in mouse macrophages suppresses Th1 cytokine profile in CD4(+) T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572992

8 July 2018

Injection with interleukin-4-secreting fibroblasts efficiently induces T helper type 2 cell-dominated immune response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572992

8 July 2018

Anti-cytokine therapy for rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572992

8 July 2018

1 Alpha,25-dihydroxyvitamin D3 inhibits differentiation, maturation, activation, and survival of dendritic cells leading to impaired alloreactive T cell activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572992

8 July 2018

Interleukin-12, a key cytokine in Th1-mediated autoimmune diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572992

8 July 2018

IL-12 as a therapeutic target for pharmacological modulation in immune-mediated and inflammatory diseases: regulation of T helper 1/T helper 2 responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572992

8 July 2018

Retinoids inhibit interleukin-12 production in macrophages through physical associations of retinoid X receptor and NFkappaB.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572992

8 July 2018

Molecular mechanisms of the induction of IL-12 and its inhibition by IL-10.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572992

8 July 2018

Cytokines induce the development of functionally heterogeneous T helper cell subsets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572992

8 July 2018

Proinflammatory and immunoregulatory functions of interleukin-12.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572992

8 July 2018

Beta2-agonists prevent Th1 development by selective inhibition of interleukin 12.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572992

8 July 2018

The mechanisms of action of disease-modifying antirheumatic drugs: a review with emphasis on macrophage signal transduction and the induction of proinflammatory cytokines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572992

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572992

8 July 2018

Induction of Th1 and Th2 CD4+ T cell responses: the alternative approaches

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572992

8 July 2018

Dendritic cells: from ontogenetic orphans to myelomonocytic descendants.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572992

8 July 2018

Effects of IL-12 in memory CD4+ T lymphocyte responses.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572992

8 July 2018

Th1 and Th2 in human diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572992

8 July 2018

IL-12 synergizes with IL-2 and other stimuli in inducing IL-10 production by human T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572992

8 July 2018

Acquisition of lymphokine-producing phenotype by CD4+ T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572992

8 July 2018

Administration of interleukin 12 in combination with type II collagen induces severe arthritis in DBA/1 mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572992

8 July 2018

Cytokine secretion phenotypes of TH cells: how many subsets, how much regulation?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572992

8 July 2018

Gold-specific T cells in rheumatoid arthritis patients treated with gold

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572992

8 July 2018

Macrophages and the glucocorticoids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572992

8 July 2018

Induction of human promyelocytic leukemia HL-60 cell differentiation into monocytes by silibinin: involvement of protein kinase C.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572992

25 October 2018

The role of IL-12 in inflammatory activity of patients with rheumatoid arthritis (RA).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572992

25 October 2018

IL-12 in autoimmunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572992

25 October 2018

Interleukin-12 primes human CD4 and CD8 T cell clones for high production of both interferon-gamma and interleukin-10.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572992

25 October 2018

Expression of cytokines and immune mediators during chronic liver allograft rejection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572992

25 October 2018

IL-12 inhibits IL-4 synthesis in keyhole limpet hemocyanin-primed CD4+ T cells through an effect on antigen-presenting cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572992

25 October 2018

IL-12 inhibits the production of IL-4 and IL-10 in allergen-specific human CD4+ T lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572992

25 October 2018

IL-12 up-regulates IL-18 receptor expression on T cells, Th1 cells, and B cells: synergism with IL-18 for IFN-gamma production

1 reference

https://pubmed.ncbi.nlm.nih.gov/11588111

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A role for Th1 and Th2 cells in the immunopathogenesis of atopic dermatitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11588111

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of Th1 development and treatment of chronic-relapsing experimental allergic encephalomyelitis by a non-hypercalcemic analogue of 1,25-dihydroxyvitamin D(3)

1 reference

https://pubmed.ncbi.nlm.nih.gov/11588111

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rheumatoid arthritis exacerbation caused by exogenous interleukin-12

1 reference

https://pubmed.ncbi.nlm.nih.gov/11588111

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of functional IL-2 receptors on mature splenic dendritic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/11588111

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidized low density lipoprotein inhibits interleukin-12 production in lipopolysaccharide-activated mouse macrophages via direct interactions between peroxisome proliferator-activated receptor-gamma and nuclear factor-kappa B

1 reference

https://pubmed.ncbi.nlm.nih.gov/11588111

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of auranofin, an antirheumatic drug, on neutrophil apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11588111

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Linkage disequilibrium of a type 1 diabetes susceptibility locus with a regulatory IL12B allele

1 reference

https://pubmed.ncbi.nlm.nih.gov/11588111

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Auranofin: a unique oral chrysotherapeutic agent

1 reference

https://pubmed.ncbi.nlm.nih.gov/11588111

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro effects of two gold compounds, and D-penicillamine on the production of interferon gamma

1 reference

https://pubmed.ncbi.nlm.nih.gov/11588111

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cooperation of natural killer cell stimulatory factor/interleukin-12 with other stimuli in the induction of cytokines and cytotoxic cell-associated molecules in human T and NK cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/11588111

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of gamma delta T cells for production of IFN-gamma is mediated by bacteria via macrophage-derived cytokines IL-1 and IL-12

1 reference

https://pubmed.ncbi.nlm.nih.gov/11588111

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Down-regulating effects of IL-4 and IL-10 on the IFN-gamma response in atopic dermatitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11588111

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of thymic B cells by signals of CD40 molecules plus interleukin-10

1 reference

https://pubmed.ncbi.nlm.nih.gov/11588111

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Auranofin inhibits the induction of interleukin 1 beta and tumor necrosis factor alpha mRNA in macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/11588111

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-12 induces human T cells secreting IL-10 with IFN-gamma

1 reference

https://pubmed.ncbi.nlm.nih.gov/11588111

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An ovalbumin-IL-12 fusion protein is more effective than ovalbumin plus free recombinant IL-12 in inducing a T helper cell type 1-dominated immune response and inhibiting antigen-specific IgE production

1 reference

https://pubmed.ncbi.nlm.nih.gov/11588111

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-1 alpha and TNF-alpha are required for IL-12-induced development of Th1 cells producing high levels of IFN-gamma in BALB/c but not C57BL/6 mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/11588111

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Corticosteroids enhance the capacity of macrophages to induce Th2 cytokine synthesis in CD4+ lymphocytes by inhibiting IL-12 production

1 reference

https://pubmed.ncbi.nlm.nih.gov/11588111

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Th1/Th2 balance in human disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/11588111

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-12 is expressed by infiltrating macrophages and synovial lining cells in rheumatoid arthritis and osteoarthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11588111

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of helper T cell subsets in autoimmune diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/11588111

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/SJ.BJP.0704298

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

ResearchGate publication ID

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