(Q35043860)

English

A novel transcription factor inhibitor, SP100030, inhibits cytokine gene expression, but not airway eosinophilia or hyperresponsiveness in sensitized and allergen-exposed rat.

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

A novel transcription factor inhibitor, SP100030, inhibits cytokine gene expression, but not airway eosinophilia or hyperresponsiveness in sensitized and allergen-exposed rat. (English)

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

author name string

T J Huang

1

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

I M Adcock

2

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

K F Chung

3

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

language of work or name

0 references

publication date

1 November 2001

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

British Journal of Pharmacology

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

134

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

5

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

1029-1036

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

The effect of a T cell-specific NF-kappa B inhibitor on in vitro cytokine production and collagen-induced arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573037

8 July 2018

Cytokines in asthma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573037

8 July 2018

Allergen-specific Th1 cells fail to counterbalance Th2 cell-induced airway hyperreactivity but cause severe airway inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573037

8 July 2018

Activation and localization of transcription factor, nuclear factor-kappaB, in asthma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573037

8 July 2018

Essential role of nuclear factor kappaB in the induction of eosinophilia in allergic airway inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573037

8 July 2018

Induction of pulmonary allergic responses by antigen-specific Th2 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573037

8 July 2018

A novel inhibitor of nuclear factor-kappa B and activator protein-1 transcription factors in T cells suppresses host-versus-graft alloreactivity in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573037

8 July 2018

Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity, and lung damage in a mouse asthma model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573037

8 July 2018

Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573037

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573037

8 July 2018

Depletion of OX-8 lymphocytes from the blood and airways using monoclonal antibodies enhances the late airway response in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573037

8 July 2018

Interleukin 10 (IL-10) inhibits the release of proinflammatory cytokines from human polymorphonuclear leukocytes. Evidence for an autocrine role of tumor necrosis factor and IL-1 beta in mediating the production of IL-8 triggered by lipopolysacchari

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573037

8 July 2018

Attenuation of allergic airway inflammation in IL-4 deficient mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573037

8 July 2018

The natural immune response to inhaled soluble protein antigens involves major histocompatibility complex (MHC) class I-restricted CD8+ T cell-mediated but MHC class II-restricted CD4+ T cell-dependent immune deviation resulting in selective suppres

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573037

8 July 2018

Interleukin 10 inhibits lipopolysaccharide-induced survival and cytokine production by human peripheral blood eosinophils

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573037

8 July 2018

Structure, regulation and function of NF-kappa B

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573037

8 July 2018

Interleukin-10 inhibits antigen-induced cellular recruitment into the airways of sensitized mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573037

8 July 2018

T-cells subsets and activation in bronchial mucosa of sensitized Brown-Norway rats after single allergen exposure.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573037

8 July 2018

Role of inflammation in the hyperreactivity of the airways in asthma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573037

8 July 2018

Interleukin-2: inception, impact, and implications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573037

8 July 2018

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573037

8 July 2018

Expression of mRNA for interleukin-5 in mucosal bronchial biopsies from asthma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573037

8 July 2018

CD4 T-lymphocyte activation in acute severe asthma. Relationship to disease severity and atopic status

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573037

8 July 2018

IL-10 acts on the antigen-presenting cell to inhibit cytokine production by Th1 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573037

8 July 2018

The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573037

8 July 2018

https://pubmed.ncbi.nlm.nih.gov/11682451

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-5, eosinophils, and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573037

8 July 2018

c-fos proto-oncogene expression in bronchial biopsies of asthmatics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573037

8 July 2018

Inhibitory effect of the TRFK-5 anti-IL-5 antibody in a guinea pig model of asthma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0704344

21 January 2018

Infection of mice with Mycobacterium bovis-Bacillus Calmette-Guérin (BCG) suppresses allergen-induced airway eosinophilia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573037

25 October 2018

Inhibition of macrophage inflammatory protein-1 alpha expression by IL-10. Differential sensitivities in human blood monocytes and alveolar macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573037

25 October 2018

Inhibitory effects of endogenous and exogenous interferon-gamma on bronchial hyperresponsiveness, allergic inflammation and T-helper 2 cytokines in Brown-Norway rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/11682451

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of interleukin-5 inhibition on antigen-induced airway hyperresponsiveness and cell accumulation in guinea pigs

1 reference

https://pubmed.ncbi.nlm.nih.gov/11682451

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of an antibody to interleukin-5 in a monkey model of asthma

1 reference

https://pubmed.ncbi.nlm.nih.gov/11682451

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Normal bronchial epithelial cells constitutively produce the anti-inflammatory cytokine interleukin-10, which is downregulated in cystic fibrosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11682451

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of airway hyperreactivity in interleukin-5 transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/11682451

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcription factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/11682451

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Depletion of CD8+ T cells enhances pulmonary inflammation but not airway responsiveness after antigen challenge in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/11682451

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SP100030 is a novel T-cell-specific transcription factor inhibitor that possesses immunosuppressive activity in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/11682451

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antiinterleukin-5 antibody prevents airway hyperresponsiveness in a murine model of airway sensitization

1 reference

https://pubmed.ncbi.nlm.nih.gov/11682451

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prevention of Th2-like cell responses by coadministration of IL-12 and IL-18 is associated with inhibition of antigen-induced airway hyperresponsiveness, eosinophilia, and serum IgE levels

1 reference

https://pubmed.ncbi.nlm.nih.gov/11682451

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inflammatory mediators of asthma: an update

1 reference

https://pubmed.ncbi.nlm.nih.gov/11682451

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

alpha4 integrin-dependent eotaxin induction of bronchial hyperresponsiveness and eosinophil migration in interleukin-5 transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/11682451

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of CD8+ T-cell depletion on bronchial hyper-responsiveness and inflammation in sensitized and allergen-exposed Brown-Norway rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/11682451

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential regulation of cytokine expression after allergen exposure of sensitized rats by cyclosporin A and corticosteroids: Relationship to bronchial hyperresponsiveness

1 reference

https://pubmed.ncbi.nlm.nih.gov/11682451

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neutrophil depletion inhibits airway hyperresponsiveness induced by ozone exposure

1 reference

https://pubmed.ncbi.nlm.nih.gov/11682451

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inflammation and the late phase reaction in asthma: the effect of polymorphonuclear leukocyte depletion on airways obstruction and bronchial hyperreactivity in an animal model

1 reference

https://pubmed.ncbi.nlm.nih.gov/11682451

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of activated T lymphocytes and eosinophils in bronchial biopsies in stable atopic asthma

1 reference

https://pubmed.ncbi.nlm.nih.gov/11682451

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of allergen-induced bronchial hyperresponsiveness and airway inflammation in actively sensitized Brown-Norway rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/11682451

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Predominant TH2-like bronchoalveolar T-lymphocyte population in atopic asthma

1 reference

https://pubmed.ncbi.nlm.nih.gov/11682451

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/SJ.BJP.0704344

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

ResearchGate publication ID

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