(Q35044537)

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Interferon signaling patterns in peripheral blood lymphocytes may predict clinical outcome after high-dose interferon therapy in melanoma patients

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scholarly article

1 reference

Europe PubMed Central

6 August 2017

Interferon signaling patterns in peripheral blood lymphocytes may predict clinical outcome after high-dose interferon therapy in melanoma patients (English)

1 reference

Europe PubMed Central

6 August 2017

author name string

Diana L Simons

1

1 reference

Europe PubMed Central

6 August 2017

Gerald Lee

2

1 reference

Europe PubMed Central

6 August 2017

John M Kirkwood

3

1 reference

Europe PubMed Central

6 August 2017

Peter P Lee

4

1 reference

Europe PubMed Central

6 August 2017

publication date

5 May 2011

1 reference

Europe PubMed Central

6 August 2017

Journal of Translational Medicine

1 reference

Europe PubMed Central

6 August 2017

9

1 reference

Europe PubMed Central

6 August 2017

52

1 reference

Europe PubMed Central

6 August 2017

https://scigraph.springernature.com/pub.10.1186/1479-5876-9-52

0 references

Major differences in the responses of primary human leukocyte subsets to IFN-beta.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114759

8 July 2018

Dissecting interferon-induced transcriptional programs in human peripheral blood cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114759

8 July 2018

Interferon alpha adjuvant therapy in patients with high-risk melanoma: a systematic review and meta-analysis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114759

8 July 2018

Clinical and immunologic basis of interferon therapy in melanoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114759

8 July 2018

Immune profile and mitotic index of metastatic melanoma lesions enhance clinical staging in predicting patient survival

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114759

8 July 2018

Impaired interferon signaling is a common immune defect in human cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114759

8 July 2018

Tumor-induced tolerance and immune suppression by myeloid derived suppressor cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114759

8 July 2018

Down-regulation of the interferon signaling pathway in T lymphocytes from patients with metastatic melanoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114759

8 July 2018

IFN-alpha-induced signal transduction, gene expression, and antitumor activity of immune effector cells are negatively regulated by suppressor of cytokine signaling proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114759

8 July 2018

IFNalpha2b stimulated release of IFNgamma differentially regulates T cell and NK cell mediated tumor cell cytotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114759

8 July 2018

Cutting Edge: The direct action of type I IFN on CD4 T cells is critical for sustaining clonal expansion in response to a viral but not a bacterial infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114759

8 July 2018

Myeloid suppressor cells in cancer: recruitment, phenotype, properties, and mechanisms of immune suppression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114759

8 July 2018

Type I interferons act directly on CD8 T cells to allow clonal expansion and memory formation in response to viral infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114759

8 July 2018

Multiparametric flow cytometric analysis of inter-patient variation in STAT1 phosphorylation following interferon Alfa immunotherapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114759

8 July 2018

Foxp3 expressing CD4+CD25(high) regulatory T cells are overrepresented in human metastatic melanoma lymph nodes and inhibit the function of infiltrating T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114759

8 July 2018

Mechanisms of Interferon-alpha induced apoptosis in malignant cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114759

8 July 2018

Elevated plasma levels of transforming growth factor (TGF)-beta1 and TGF-beta2 in patients with disseminated malignant melanoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114759

8 July 2018

Demonstration of an interferon gamma-dependent tumor surveillance system in immunocompetent mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114759

8 July 2018

Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114759

8 July 2018

Prognostic value of tumor infiltrating lymphocytes in the vertical growth phase of primary cutaneous melanoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114759

8 July 2018

Reporting results of cancer treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114759

8 July 2018

Phase II trial of recombinant leukocyte A interferon in advanced malignant melanoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114759

8 July 2018

Recombinant interferons in the management of advanced malignant melanoma. Updated review of five prospective clinical trials and long-term responders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114759

8 July 2018

Microvascular injury in pathogenesis of interferon-induced necrosis of subcutaneous tumors in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114759

8 July 2018

A pooled analysis of eastern cooperative oncology group and intergroup trials of adjuvant high-dose interferon for melanoma.

1 reference

https://api.crossref.org/works/10.1186%2F1479-5876-9-52

21 January 2018

Does adjuvant interferon-alpha for high-risk melanoma provide a worthwhile benefit? A meta-analysis of the randomised trials.

1 reference

https://api.crossref.org/works/10.1186%2F1479-5876-9-52

21 January 2018

Interferon alpha as adjuvant postsurgical treatment of melanoma: a meta-analysis.

1 reference

https://api.crossref.org/works/10.1186%2F1479-5876-9-52

21 January 2018

Randomized trial of an allogeneic melanoma lysate vaccine with low-dose interferon Alfa-2b compared with high-dose interferon Alfa-2b for Resected stage III cutaneous melanoma

1 reference

https://api.crossref.org/works/10.1186%2F1479-5876-9-52

21 January 2018

Prognostic significance of autoimmunity during treatment of melanoma with interferon.

1 reference

https://api.crossref.org/works/10.1186%2F1479-5876-9-52

21 January 2018

Multiplex analysis of serum cytokines in melanoma patients treated with interferon-alpha2b.

1 reference

https://api.crossref.org/works/10.1186%2F1479-5876-9-52

21 January 2018

IFN-alpha amplifies human naive B cell TLR-9-mediated activation and Ig production.

1 reference

https://api.crossref.org/works/10.1186%2F1479-5876-9-52

21 January 2018

A flow cytometric method for determination of the interferon receptor IFNAR2 subunit in peripheral blood leukocyte subsets

1 reference

https://api.crossref.org/works/10.1186%2F1479-5876-9-52

21 January 2018

Multiparametric flow cytometric analysis of signal transducer and activator of transcription 5 phosphorylation in immune cell subsets in vitro and following interleukin-2 immunotherapy.

1 reference

https://api.crossref.org/works/10.1186%2F1479-5876-9-52

21 January 2018

Modulation of signal transducers and activators of transcription 1 and 3 signaling in melanoma by high-dose IFNalpha2b.

1 reference

https://api.crossref.org/works/10.1186%2F1479-5876-9-52

21 January 2018

Interferon-alpha treatment may negatively influence disease progression in melanoma patients by hyperactivation of STAT3 protein

1 reference

https://api.crossref.org/works/10.1186%2F1479-5876-9-52

21 January 2018

Cutting edge: enhancement of antibody responses through direct stimulation of B and T cells by type I IFN.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114759

25 October 2018

TGF-beta1 inhibits T-bet induction by IFN-gamma in murine CD4+ T cells through the protein tyrosine phosphatase Src homology region 2 domain-containing phosphatase-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114759

25 October 2018

The possible role of TGF-beta-induced suppressors of cytokine signaling expression in osteoclast/macrophage lineage commitment in vitro.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114759

25 October 2018

Randomized phase III study of 1 month versus 1 year of adjuvant high-dose interferon alfa-2b in patients with resected high-risk melanoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/21545749

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interferon-alpha regulates the dynamic balance between human activated regulatory and effector T cells: implications for antiviral and autoimmune responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/21545749

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An elevated serum level of transforming growth factor-beta 1 (TGF-beta 1) significantly correlated with lymph node metastasis and poor prognosis in patients with gastric carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/21545749

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interferon-alpha activates cytotoxic function but inhibits interleukin-2-mediated proliferation and tumor necrosis factor-alpha secretion by immature human natural killer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21545749

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A dual role of IFN-alpha in the balance between proliferation and death of human CD4+ T lymphocytes during primary response

1 reference

https://pubmed.ncbi.nlm.nih.gov/21545749

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-10 inhibits expression of both interferon alpha- and interferon gamma- induced genes by suppressing tyrosine phosphorylation of STAT1

1 reference

https://pubmed.ncbi.nlm.nih.gov/21545749

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Type I IFNs provide a third signal to CD8 T cells to stimulate clonal expansion and differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/21545749

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neoadjuvant treatment of regional stage IIIB melanoma with high-dose interferon alfa-2b induces objective tumor regression in association with modulation of tumor infiltrating host cellular immune responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/21545749

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/1479-5876-9-52

1 reference

Europe PubMed Central

6 August 2017

Dimensions Publication ID

0 references

release_deyj5ohpffgdbmtttcrdmc2cgq

1 reference

https://api.fatcat.wiki/v0/release/deyj5ohpffgdbmtttcrdmc2cgq

24 November 2022

based on heuristic

mapped directly with Wikidata item

Internet Archive ID

pubmed-PMC3114759

0 references

1 reference

Europe PubMed Central

6 August 2017

1 reference

Europe PubMed Central

6 August 2017

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