(Q35045023)

6 August 2017

title

Role of Th2 responses in the development of allergen-induced airway remodelling in a murine model of allergic asthma (English)

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6 August 2017

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Masato Komai

1

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6 August 2017

Hiroyuki Tanaka

2

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6 August 2017

Taisei Masuda

3

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6 August 2017

Koichi Nagao

4

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6 August 2017

Masayuki Ishizaki

5

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6 August 2017

Masatsugu Sawada

6

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6 August 2017

Hiroichi Nagai

7

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6 August 2017

language of work or name

English

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publication date

1 March 2003

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British Journal of Pharmacology

6 August 2017

published in

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6 August 2017

volume

138

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6 August 2017

issue

5

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6 August 2017

page(s)

912-920

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Interleukin-13 induces tissue fibrosis by selectively stimulating and activating transforming growth factor beta(1).

6 August 2017

cites work

1 reference

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Th-2 cytokines in allergic disease

8 July 2018

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Role of transforming growth factor beta in human disease

8 July 2018

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A preliminary study of long-term treatment with interferon gamma-1b and low-dose prednisolone in patients with idiopathic pulmonary fibrosis

8 July 2018

1 reference

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An IL-13 inhibitor blocks the development of hepatic fibrosis during a T-helper type 2-dominated inflammatory response

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573716

Transient gene transfer and expression of Smad7 prevents bleomycin-induced lung fibrosis in mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573716

Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573716

Inhibition of transforming growth factor-beta/SMAD signalling by the interferon-gamma/STAT pathway.

8 July 2018

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Interleukin-13: central mediator of allergic asthma

8 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573716

Randomised, dose-ranging, placebo-controlled study of chimeric antibody to CD4 (keliximab) in chronic severe asthma

8 July 2018

1 reference

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Interleukin (IL) 4 and IL-13 act on human lung fibroblasts. Implication in asthma.

8 July 2018

1 reference

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TGF-beta signalling from cell membrane to nucleus through SMAD proteins

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573716

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573716

Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity, and lung damage in a mouse asthma model

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573716

Interleukin 13, a T-cell-derived cytokine that regulates human monocyte and B-cell function

8 July 2018

1 reference

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Transforming growth factor beta in tissue fibrosis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573716

Asthma and irreversible airflow obstruction

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573716

Purified interleukin 5 supports the terminal differentiation and proliferation of murine eosinophilic precursors

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573716

Recombinant gamma, alpha, and beta interferon regulation of human lung fibroblast proliferation.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573716

Recombinant human interleukin 5 is a selective activator of human eosinophil function

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573716

IL-4 is required to generate and sustain in vivo IgE responses

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573716

Mucosal inflammation in asthma

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573716

Effects of treatment on airway inflammation and thickening of basement membrane reticular collagen in asthma. A quantitative light and electron microscopic study

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573716

CD4(+) T-lymphocytes regulate airway remodeling and hyper-reactivity in a mouse model of chronic asthma.

8 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FSJ.BJP.0705105

Persistent airway hyperresponsiveness and histologic alterations after chronic antigen challenge in cats.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FSJ.BJP.0705105

A novel role for murine IL-4 in vivo: induction of MUC5AC gene expression and mucin hypersecretion.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FSJ.BJP.0705105

The effect of allergen-induced airway inflammation on airway remodeling in a murine model of allergic asthma

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573716

Requirement for IL-13 independently of IL-4 in experimental asthma

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573716

The role of IL-13 and its receptor in allergy and inflammatory responses.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573716

Disruption of the murine IL-4 gene blocks Th2 cytokine responses.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573716

Muc-5/5ac mucin messenger RNA and protein expression is a marker of goblet cell metaplasia in murine airways

25 October 2018

1 reference

12 December 2020

Dissociation of inflammatory and epithelial responses in a murine model of chronic asthma

1 reference

12 December 2020

Antagonistic regulation of type I collagen gene expression by interferon-gamma and transforming growth factor-beta. Integration at the level of p300/CBP transcriptional coactivators

1 reference

12 December 2020

Modifications of a specific assay for hydroxyproline in urine

1 reference

12 December 2020

Inhibition of fibroblast chemotaxis by recombinant human interferon gamma and interferon alpha

1 reference

12 December 2020

SUBEPITHELIAL FIBROSIS IN THE BRONCHI OF ASTHMATICS

1 reference

12 December 2020

Marked goblet cell hyperplasia with mucus accumulation in the airways of patients who died of severe acute asthma attack

1 reference

12 December 2020

CD4+ T-lymphocytes and interleukin-5 mediate antigen-induced eosinophil infiltration into the mouse trachea

1 reference

12 December 2020

Depletion of murine CD4+ T lymphocytes prevents antigen-induced airway hyperreactivity and pulmonary eosinophilia

1 reference

12 December 2020

Transforming growth factor-beta expression in mucosal biopsies in asthma and chronic bronchitis

1 reference

12 December 2020

Eosinophil-associated TGF-beta1 mRNA expression and airways fibrosis in bronchial asthma

1 reference

12 December 2020

What causes airway remodelling in asthma?

1 reference

12 December 2020

Susceptibility to Leishmania major infection in interleukin-4-deficient mice

1 reference

12 December 2020

The effect of anti-IL-4 monoclonal antibody, rapamycin and interferon-gamma on airway hyperreactivity to acetylcholine in mice

1 reference

12 December 2020

An essential role of mast cells in the development of airway hyperresponsiveness in a murine asthma model

1 reference

12 December 2020

Identifiers

DOI

10.1038/SJ.BJP.0705105

1 reference

6 August 2017

1 reference

6 August 2017

1 reference