(Q35047701)

6 August 2017

title

Alterations in glucose metabolism by cyclosporine in rat brain slices link to oxidative stress: interactions with mTOR inhibitors (English)

1 reference

6 August 2017

1 reference

Uwe Christians

1

1 reference

6 August 2017

Sven Gottschalk

2

1 reference

6 August 2017

Jelena Miljus

3

1 reference

6 August 2017

Carsten Hainz

4

1 reference

6 August 2017

Leslie Z Benet

5

1 reference

6 August 2017

Dieter Leibfritz

6

1 reference

6 August 2017

Natalie Serkova

7

1 reference

6 August 2017

language of work or name

English

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publication date

31 August 2004

1 reference

British Journal of Pharmacology

6 August 2017

published in

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6 August 2017

volume

143

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6 August 2017

issue

3

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6 August 2017

page(s)

388-396

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Transplantation: toxicokinetics and mechanisms of toxicity of cyclosporine and macrolides.

6 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1575349

Exposure-response relationships for everolimus in de novo kidney transplantation: defining a therapeutic range

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1575349

Early clinical experience with a novel rapamycin derivative

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1575349

Neurotoxicity of immunosuppressive drugs

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1575349

Sirolimus, but not the structurally related RAD (everolimus), enhances the negative effects of cyclosporine on mitochondrial metabolism in the rat brain

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1575349

Median effect analysis of efficacy versus adverse effects of immunosuppressants

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1575349

mTOR inhibitors: an overview

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1575349

Longitudinal assessment of everolimus in de novo renal transplant recipients over the first post-transplant year: pharmacokinetics, exposure-response relationships, and influence on cyclosporine

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1575349

Neurotoxicity of calcineurin inhibitors: impact and clinical management.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1575349

The novel immunosuppressant SDZ-RAD protects rat brain slices from cyclosporine-induced reduction of high-energy phosphates

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1575349

Cyclosporine neurotoxicity: a review

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1575349

Newer immunosuppressive drugs: a review.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1575349

An introduction to the potential of 1H-, 31P- and 13C-NMR-spectroscopy

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1575349

Cyclosporine nephrotoxicity: attenuation by an antioxidant-inhibitor of lipid peroxidation in vitro and in vivo.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1575349

Cyclosporin. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in immunoregulatory disorders

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1575349

Regulation of cellular energy metabolism

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1575349

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1575349

The mechanism of action of cyclosporin A and FK506

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1575349

Comparison of the effects of cyclosporin a on the metabolism of perfused rat brain slices during normoxia and hypoxia

8 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FSJ.BJP.0705939

Understanding 'Global' Systems Biology: Metabonomics and the Continuum of Metabolism

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1575349

Organ-specific response to inhibition of mitochondrial metabolism by cyclosporine in the rat.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1575349

Elevated basal ganglia glucose metabolism in cyclosporine neurotoxicity: a positron emission tomography imaging study

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1575349

Effect of low dose cyclosporine and sirolimus on hepatic drug metabolism in the rat1.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1575349

Effects of the novel cyclosporine derivative PSC833 on glucose metabolism in rat primary cultures of neuronal and glial cells

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1575349

Pharmacokinetic interactions augment toxicities of sirolimus/cyclosporine combinations.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1575349

Evaluation of individual and combined neurotoxicity of the immunosuppressants cyclosporine and sirolimus by in vitro multinuclear NMR spectroscopy

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1575349

Efficacy of sirolimus compared with azathioprine for reduction of acute renal allograft rejection: a randomised multicentre study

25 October 2018

1 reference

12 December 2020

Impact on energy metabolism of quantitative and functional cyclosporine-induced damage of kidney mitochondria

1 reference

12 December 2020

Effect of cyclosporine on oxidative phosphorylation and adenylate energy charge of regenerating rat liver

1 reference

12 December 2020

31P-NMR studies of isolated adult heart cells: effect of myoglobin inactivation

1 reference

12 December 2020

Synergistic effects of cyclosporine and rapamycin in a chronic nephrotoxicity model

1 reference

12 December 2020

Rapamycin inhibits aldolase A expression during human lymphocyte activation

1 reference

12 December 2020

The synergistic effects of cyclosporine and sirolimus

1 reference

12 December 2020

Cyclosporine A-induced oxidative stress in rat hepatocytes

1 reference

12 December 2020

SDZ RAD, a new rapamycin derivative: synergism with cyclosporine

1 reference

12 December 2020

Oral administration of rapamycin and cyclosporine differentially alter intestinal function in rabbits

1 reference

12 December 2020

Cyclosporine increases local glomerular synthesis of reactive oxygen species in rats: effect of vitamin E on cyclosporine nephrotoxicity

1 reference

12 December 2020

Quantifying cellular oxidative stress by dichlorofluorescein assay using microplate reader

1 reference

12 December 2020

31P and 1H NMR spectroscopic studies of liver extracts of carbon tetrachloride-treated rats

1 reference

12 December 2020

Identifiers

DOI

10.1038/SJ.BJP.0705939

1 reference

6 August 2017

1 reference

6 August 2017

1 reference