(Q35048220)

English

Characterization of gap junction remodeling in epicardial border zone of healing canine infarcts and electrophysiological effects of partial reversal by rotigaptide

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scholarly article

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28 January 2020

Characterization of gap junction remodeling in epicardial border zone of healing canine infarcts and electrophysiological effects of partial reversal by rotigaptide (English)

1 reference

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28 January 2020

electrophysiology

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electrophysiological effect

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Alexandra Z Sosinsky

4

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28 January 2020

author name string

Ester Macia

1

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28 January 2020

Elena Dolmatova

2

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28 January 2020

Candido Cabo

3

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28 January 2020

Wen Dun

5

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28 January 2020

James Coromilas

6

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28 January 2020

Edward J Ciaccio

7

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28 January 2020

Penelope A Boyden

8

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28 January 2020

Andrew L Wit

9

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28 January 2020

Heather S Duffy

10

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28 January 2020

publication date

14 April 2011

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28 January 2020

Circulation: Arrhythmia and Electrophysiology

1 reference

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28 January 2020

4

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28 January 2020

3

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28 January 2020

344-351

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28 January 2020

Phosphorylation of connexin43 on serine 306 regulates electrical coupling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116056

8 July 2018

Structural and molecular mechanisms of gap junction remodeling in epicardial border zone myocytes following myocardial infarction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116056

8 July 2018

Connexin43 phosphorylation: structural changes and biological effects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116056

8 July 2018

Remodelling of gap junctions and connexin expression in diseased myocardium.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116056

8 July 2018

Enhancement of ventricular gap-junction coupling by rotigaptide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116056

8 July 2018

Phosphorylation at S365 is a gatekeeper event that changes the structure of Cx43 and prevents down-regulation by PKC.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116056

8 July 2018

Maintenance of intercellular coupling by the antiarrhythmic peptide rotigaptide suppresses arrhythmogenic discordant alternans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116056

8 July 2018

Key connexin 43 phosphorylation events regulate the gap junction life cycle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116056

8 July 2018

Analysis of Connexin43 phosphorylated at S325, S328 and S330 in normoxic and ischemic heart

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116056

8 July 2018

Selectivity of connexin 43 channels is regulated through protein kinase C-dependent phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116056

8 July 2018

Cell-to-cell electrical interactions during early and late repolarization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116056

8 July 2018

Identification of ischemia-regulated phosphorylation sites in connexin43: A possible target for the antiarrhythmic peptide analogue rotigaptide (ZP123).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116056

8 July 2018

Connexin phosphorylation as a regulatory event linked to gap junction internalization and degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116056

8 July 2018

Connexin phosphorylation as a regulatory event linked to gap junction channel assembly

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116056

8 July 2018

Modulation of cardiac gap junction expression and arrhythmic susceptibility.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116056

8 July 2018

The effects of connexin phosphorylation on gap junctional communication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116056

8 July 2018

Regulation of purified and reconstituted connexin 43 hemichannels by protein kinase C-mediated phosphorylation of Serine 368.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116056

8 July 2018

Pharmacological modulation of cardiac gap junctions to enhance cardiac conduction: evidence supporting a novel target for antiarrhythmic therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116056

8 July 2018

Plasma membrane channels formed by connexins: their regulation and functions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116056

8 July 2018

Phosphorylation of connexin43 on serine368 by protein kinase C regulates gap junctional communication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116056

8 July 2018

Disturbed connexin43 gap junction distribution correlates with the location of reentrant circuits in the epicardial border zone of healing canine infarcts that cause ventricular tachycardia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116056

8 July 2018

Reentrant ventricular arrhythmias in the late myocardial infarction period in the dog. 13. Correlation of activation and refractory maps.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116056

8 July 2018

Electrophysiologic and anatomic basis for fractionated electrograms recorded from healed myocardial infarcts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116056

8 July 2018

Electrical uncoupling and increase of extracellular resistance after induction of ischemia in isolated, arterially perfused rabbit papillary muscle.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116056

8 July 2018

Influences of anisotropic tissue structure on reentrant circuits in the epicardial border zone of subacute canine infarcts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116056

8 July 2018

Cellular uncoupling can unmask dispersion of action potential duration in ventricular myocardium. A computer modeling study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116056

8 July 2018

Electrotonic influences on action potentials from isolated ventricular cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116056

8 July 2018

Effects of the gap junction modifier rotigaptide (ZP123) on atrial conduction and vulnerability to atrial fibrillation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116056

25 October 2018

Rotigaptide (ZP123) prevents spontaneous ventricular arrhythmias and reduces infarct size during myocardial ischemia/reperfusion injury in open-chest dogs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116056

25 October 2018

ZP123 increases gap junctional conductance and prevents reentrant ventricular tachycardia during myocardial ischemia in open chest dogs.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116056

25 October 2018

Electrophysiological effects of flecainide on anisotropic conduction and reentry in infarcted canine hearts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116056

25 October 2018

Heterogeneous gap junction remodeling in reentrant circuits in the epicardial border zone of the healing canine infarct

1 reference

https://pubmed.ncbi.nlm.nih.gov/21493965

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Model-dependent effects of the gap junction conduction-enhancing antiarrhythmic peptide rotigaptide (ZP123) on experimental atrial fibrillation in dogs

1 reference

https://pubmed.ncbi.nlm.nih.gov/21493965

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of enhanced gap junctional conductance on ventricular conduction in explanted hearts from patients with heart failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/21493965

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dephosphorylation and intracellular redistribution of ventricular connexin43 during electrical uncoupling induced by ischemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/21493965

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacological modification of gap junction coupling by an antiarrhythmic peptide via protein kinase C activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/21493965

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Remodeling of gap junctional channel function in epicardial border zone of healing canine infarcts

1 reference

https://pubmed.ncbi.nlm.nih.gov/21493965

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacological characterization of the new stable antiarrhythmic peptide analog Ac-D-Tyr-D-Pro-D-Hyp-Gly-D-Ala-Gly-NH2 (ZP123): in vivo and in vitro studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/21493965

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transmural electrophysiological heterogeneities underlying arrhythmogenesis in heart failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/21493965

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of the new antiarrhythmic peptide ZP123 on epicardial activation and repolarization pattern

1 reference

https://pubmed.ncbi.nlm.nih.gov/21493965

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regional differences in electrophysiological properties of epicardium, midmyocardium, and endocardium. In vitro and in vivo correlations

1 reference

https://pubmed.ncbi.nlm.nih.gov/21493965

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alterations of Na+ currents in myocytes from epicardial border zone of the infarcted heart. A possible ionic mechanism for reduced excitability and postrepolarization refractoriness

1 reference

https://pubmed.ncbi.nlm.nih.gov/21493965

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The antiarrhythmic peptide analog ZP123 prevents atrial conduction slowing during metabolic stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/21493965

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1161/CIRCEP.110.959312

1 reference

Europe PubMed Central

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28 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21493965%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21493965%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

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