(Q35049558)

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Inhibition of GSK-3β rescues the impairments in bone formation and mechanical properties associated with fracture healing in osteoblast selective connexin 43 deficient mice

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Europe PubMed Central

PubMed publication ID

6 August 2017

Inhibition of GSK-3β rescues the impairments in bone formation and mechanical properties associated with fracture healing in osteoblast selective connexin 43 deficient mice (English)

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

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1 reference

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author name string

Alayna E Loiselle

1

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Shane A J Lloyd

2

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Emmanuel M Paul

3

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Gregory S Lewis

4

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Henry J Donahue

5

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Europe PubMed Central

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6 August 2017

language of work or name

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publication date

8 November 2013

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Europe PubMed Central

PubMed publication ID

6 August 2017

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

8

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

11

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

e81399

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

copyright license

Creative Commons Attribution 4.0 International

8 November 2013

1 reference

April 2022 Public Data File from Crossref

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Connexin 43 deficiency desensitizes bone to the effects of mechanical unloading through modulation of both arms of bone remodeling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832658

8 July 2018

Absence of Cx43 selectively from osteocytes enhances responsiveness to mechanical force in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832658

8 July 2018

Standardized nomenclature, symbols, and units for bone histomorphometry: a 2012 update of the report of the ASBMR Histomorphometry Nomenclature Committee

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832658

8 July 2018

Enhanced periosteal and endocortical responses to axial tibial compression loading in conditional connexin43 deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832658

8 July 2018

Osteoblast and osteocyte-specific loss of Connexin43 results in delayed bone formation and healing during murine fracture healing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832658

8 July 2018

Connexin 43 deficiency attenuates loss of trabecular bone and prevents suppression of cortical bone formation during unloading

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832658

8 July 2018

Cell autonomous requirement of connexin 43 for osteocyte survival: consequences for endocortical resorption and periosteal bone formation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832658

8 July 2018

Delayed osteoblastic differentiation and bone development in Cx43 knockout mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832658

8 July 2018

Enhanced osteoclastic resorption and responsiveness to mechanical load in gap junction deficient bone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832658

8 July 2018

The gap junction protein Cx43 regulates B-lymphocyte spreading and adhesion.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832658

8 July 2018

Connexin43 deficiency reduces the sensitivity of cortical bone to the effects of muscle paralysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832658

8 July 2018

Osteoblast connexin43 modulates skeletal architecture by regulating both arms of bone remodeling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832658

8 July 2018

A microRNA regulatory mechanism of osteoblast differentiation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832658

8 July 2018

A role for connexin43 in macrophage phagocytosis and host survival after bacterial peritoneal infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832658

8 July 2018

Bone remodeling during fracture repair: The cellular picture.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832658

8 July 2018

Attenuated response to in vivo mechanical loading in mice with conditional osteoblast ablation of the connexin43 gene (Gja1).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832658

8 July 2018

Beta-catenin signaling plays a disparate role in different phases of fracture repair: implications for therapy to improve bone healing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832658

8 July 2018

Mechanically stimulated osteocytes regulate osteoblastic activity via gap junctions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832658

8 July 2018

Mechanical loading stimulates expression of connexin 43 in alveolar bone cells in the tooth movement model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832658

8 July 2018

Modulation of connexin43 alters expression of osteoblastic differentiation markers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832658

8 July 2018

Fluid flow-induced prostaglandin E2 response of osteoblastic ROS 17/2.8 cells is gap junction-mediated and independent of cytosolic calcium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832658

8 July 2018

Fracture healing as a post-natal developmental process: molecular, spatial, and temporal aspects of its regulation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832658

8 July 2018

Transduction of cell survival signals by connexin-43 hemichannels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832658

8 July 2018

Gap junctions and fluid flow response in MC3T3-E1 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832658

8 July 2018

The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832658

8 July 2018

Enhancement of connexin 43 expression increases proliferation and differentiation of an osteoblast-like cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832658

8 July 2018

Connexin43 deficiency causes delayed ossification, craniofacial abnormalities, and osteoblast dysfunction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832658

8 July 2018

Gap junctions and biophysical regulation of bone cell differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832658

8 July 2018

Functional gap junctions between osteocytic and osteoblastic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832658

8 July 2018

Regulation of LEF-1/TCF transcription factors by Wnt and other signals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832658

8 July 2018

Three-dimensional structure of a recombinant gap junction membrane channel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832658

8 July 2018

Gap junctional communication modulates gene expression in osteoblastic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832658

8 July 2018

Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832658

8 July 2018

Increased expression of TGF-beta 2 in osteoblasts results in an osteoporosis-like phenotype

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832658

8 July 2018

Cardiac malformation in neonatal mice lacking connexin43.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832658

8 July 2018

Low peak bone mass and attenuated anabolic response to parathyroid hormone in mice with an osteoblast-specific deletion of connexin43.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0081399

21 January 2018

Mouse alpha1(I)-collagen promoter is the best known promoter to drive efficient Cre recombinase expression in osteoblast

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0081399

21 January 2018

Development of mice with osteoblast-specific connexin43 gene deletion.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0081399

21 January 2018

Expression and activity of osteoblast-targeted Cre recombinase transgenes in murine skeletal tissues.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0081399

21 January 2018

Cross-regulation of the Wnt signalling pathway: a role of MAP kinases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832658

25 October 2018

Heart and neural tube defects in transgenic mice overexpressing the Cx43 gap junction gene.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3832658

25 October 2018

Production of a standard closed fracture in laboratory animal bone

1 reference

https://pubmed.ncbi.nlm.nih.gov/24260576

12 December 2020

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10.1371/JOURNAL.PONE.0081399

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

2013PLoSO...881399L

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PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

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