(Q35050412)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12540276%20AND%20SRC:MED&resulttype=core&format=json

17 December 2019

title

Regulation of microglia - potential new drug targets in the CNS (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12540276%20AND%20SRC:MED&resulttype=core&format=json

17 December 2019

0 references

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12540276%20AND%20SRC:MED&resulttype=core&format=json

17 December 2019

author name string

Håkan Aldskogius

series ordinal

1

1 reference

6 August 2017

language of work or name

English

0 references

publication date

1 December 2001

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12540276%20AND%20SRC:MED&resulttype=core&format=json

Expert Opinion on Therapeutic Targets

17 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12540276%20AND%20SRC:MED&resulttype=core&format=json

17 December 2019

volume

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12540276%20AND%20SRC:MED&resulttype=core&format=json

17 December 2019

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12540276%20AND%20SRC:MED&resulttype=core&format=json

17 December 2019

page(s)

655-668

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12540276%20AND%20SRC:MED&resulttype=core&format=json

The origin and nature of ramified and amoeboid microglia: a historical review and current concepts

17 December 2019

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The origin and differentiation of microglial cells during development

21 January 2018

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Characterization of microglia and macrophages in the central nervous system of rats: definition of the differential expression of molecules using standard and novel monoclonal antibodies in normal CNS and in four models of parenchymal reaction

21 January 2018

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Heterogeneity of microglial and perivascular cell populations: insights gained from the facial nucleus paradigm

21 January 2018

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Perivascular microglial cells of the CNS are bone marrow-derived and present antigen in vivo

21 January 2018

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Differential expression of inflammatory mediators in rat microglia cultured from different brain regions

21 January 2018

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Enlarged and phagocytic, but not primed, interleukin-1 alpha-immunoreactive microglia increase with age in normal human brain

21 January 2018

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Microglia: a sensor for pathological events in the CNS

21 January 2018

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21 January 2018

Reactive microgliosis

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Central neuron-glial and glial-glial interactions following axon injury

21 January 2018

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Microglia as mediators of inflammatory and degenerative diseases

21 January 2018

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The role of microglia and macrophages in the pathophysiology of the CNS.

21 January 2018

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Microglia in neurodegeneration: molecular aspects

21 January 2018

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The HHQK domain of beta-amyloid provides a structural basis for the immunopathology of Alzheimer's disease

21 January 2018

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The importance of inflammatory mechanisms in Alzheimer disease

21 January 2018

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Microglia and Alzheimer's disease

21 January 2018

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Inflammation and Alzheimer's disease

21 January 2018

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Role of macrophage activation in the pathogenesis of Alzheimer's disease and human immunodeficiency virus type 1-associated dementia

21 January 2018

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Human immunodeficiency virus and the brain

21 January 2018

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Neuronal injury associated with HIV-1: approaches to treatment

21 January 2018

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Pathways to neuronal injury and apoptosis in HIV-associated dementia.

21 January 2018

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Oxidative stress and neuroAIDS: triggers, modulators and novel antioxidants.

21 January 2018

1 reference

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Microglial cells respond to amyloidogenic PrP peptide by the production of inflammatory cytokines

21 January 2018

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Immunological and aetiological aspects of macular degeneration

21 January 2018

1 reference

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Retina-derived microglial cells induce photoreceptor cell death in vitro

21 January 2018

1 reference

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Pathogenesis of tissue injury in MS lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.655

Phagocytosis of myelin in demyelinative disease: a review.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.655

Axon damage and repair in multiple sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.655

Inflammation and glial responses in ischemic brain lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.655

Cellular inflammatory response associated with breakdown of the blood-brain barrier after closed head injury in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.655

Increased complement biosynthesis by microglia and complement activation on neurons in Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.655

Inflammatory regulators in Parkinson's disease: iNOS, lipocortin-1, and cyclooxygenases-1 and -2.

21 January 2018

1 reference

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Microglial reaction in the rat cerebral cortex induced by cortical spreading depression

21 January 2018

1 reference

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Soman-induced seizures rapidly activate astrocytes and microglia in discrete brain regions.

21 January 2018

1 reference

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The role of cytokines and growth factors in seizures and their sequelae

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.655

CXCR4-activated astrocyte glutamate release via TNFalpha: amplification by microglia triggers neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.655

An in vitro model for the study of microglia-induced neurodegeneration: involvement of nitric oxide and tumor necrosis factor-alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.655

Complement components of the innate immune system in health and disease in the CNS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.655

The role of complement anaphylatoxin C5a in neurodegeneration: implications in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.655

Complement association with neurons and beta-amyloid deposition in the brains of aged individuals with Down Syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.655

The C5a complement activation peptide increases IL-1beta and IL-6 release from amyloid-beta primed human monocytes: implications for Alzheimer's disease

21 January 2018

1 reference

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Tumor necrosis factor-alpha induces apoptosis in immortalized hypothalamic neurons: involvement of ceramide-generating pathways

21 January 2018

1 reference

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Increased expression of cyclooxygenases and peroxisome proliferator-activated receptor-gamma in Alzheimer's disease brains

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.655

P2Z purinoreceptor ligation induces activation of caspases with distinct roles in apoptotic and necrotic alterations of cell death

21 January 2018

1 reference

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Expression of inducible nitric oxide synthase, interleukin-1 and caspase-1 in HIV-1 encephalitis.

21 January 2018

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A revised view of the central nervous system microenvironment and major histocompatibility complex class II antigen presentation

21 January 2018

1 reference

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Purinergic modulation of interleukin-1 beta release from microglial cells stimulated with bacterial endotoxin

21 January 2018

1 reference

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The extracellular calcium-sensing receptor is expressed in rat microglia and modulates an outward K+ channel

21 January 2018

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Ion channels in cultured microglia.

21 January 2018

1 reference

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Complement factor C5a and epidermal growth factor trigger the activation of outward potassium currents in cultured murine microglia.

21 January 2018

1 reference

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Identification of macrophage migration inhibitory factor mRNA expression in neural cells of the rat brain by in situ hybridization

21 January 2018

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Astrocytes modulate macrophage phagocytosis of myelin in vitro

21 January 2018

1 reference

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Neurons reduce glial responses to lipopolysaccharide (LPS) and prevent injury of microglial cells from over-activation by LPS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.655

Anti-inflammatory drugs: a hope for Alzheimer's disease?

21 January 2018

1 reference

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Neuroprotection for ischaemic stroke: an unattainable goal?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.655

CCR3 and CCR5 are co-receptors for HIV-1 infection of microglia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.655

Mice deficient in tumor necrosis factor-alpha are resistant to skin carcinogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.655

From theory to therapy: implications from an in vitro model of ramified microglia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.655

Effects of incorporation of immunoglobulin G and complement component C1q on uptake and degradation of Alzheimer's disease amyloid fibrils by microglia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.655

Complement component C1q modulates the phagocytosis of Abeta by microglia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.655

Alzheimer's disease and inflammation: a review of cellular and therapeutic mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.655

Glial modulating and neurotrophic properties of propentofylline and its application to Alzheimer's disease and vascular dementia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.655

Cascading glia reactions: a common pathomechanism and its differentiated control by cyclic nucleotide signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.655

Neuromodulatory effect of propentofylline on rat brain under acute and long-term hypoperfusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.655

Transforming growth factor-betas in neurodegenerative disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.655

TGF-beta1 promotes microglial amyloid-beta clearance and reduces plaque burden in transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.655

Activators of peroxisome proliferator-activated receptor-gamma (PPARgamma) inhibit inducible nitric oxide synthase expression but increase heme oxygenase-1 expression in rat glial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.655

Effects of macrophage migration inhibitory factor and macrophage migration stimulatory factor on function and survival of foetal dopaminergic grafts in the 6-hydroxydopamine rat model of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.655

Proteasome blockers inhibit TNF-alpha release by lipopolysaccharide stimulated macrophages and microglia: implications for HIV-1 dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.655

Effects of vesnarinone on cytokine production and activation of murine microglia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.655

Reduction in glial immunity and neuropathology by a PAF antagonist and an MMP and TNFalpha inhibitor in SCID mice with HIV-1 encephalitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.655

Effect of 17-beta-estradiol and ginsenoside Rg1 on reactive microglia induced by beta-amyloid peptides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.655

Brain-derived neurotrophic factor in astrocytes, oligodendrocytes, and microglia/macrophages after spinal cord injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.655

Up-regulation of glial cell line-derived neurotrophic factor (GDNF) following traumatic spinal cord injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.655

Distinctive patterns of PDGF-A, FGF-2, IGF-I, and TGF-beta1 gene expression during remyelination of experimentally-induced spinal cord demyelination.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.655

The role of macrophages in Wallerian degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.655

Regulation of matrix metalloproteinase expressions in astrocytes, microglia and neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.655

High concentrations of extracellular potassium enhance bacterial endotoxin lipopolysaccharide-induced neurotoxicity in glia–neuron mixed cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.5.6.655

21 January 2018

Identifiers

DOI

10.1517/14728222.5.6.655

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12540276%20AND%20SRC:MED&resulttype=core&format=json

17 December 2019

1 reference