(Q35053049)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24278023%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

title

Brd4 is displaced from HPV replication factories as they expand and amplify viral DNA (English)

1 reference

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1 March 2020

8

1 reference

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1 March 2020

Hans Luecke

5

1 reference

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1 March 2020

author name string

Nozomi Sakakibara

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24278023%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Dan Chen

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24278023%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Moon Kyoo Jang

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24278023%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Dong Wook Kang

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24278023%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Shwu-Yuan Wu

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24278023%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Cheng-Ming Chiang

7

1 reference

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1 March 2020

publication date

21 November 2013

1 reference

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1 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24278023%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

volume

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24278023%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

issue

11

1 reference

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1 March 2020

page(s)

e1003777

1 reference

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Creative Commons CC0 License

1 March 2020

copyright license

start time

21 November 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted, dedicated to the public domain by copyright holder

0 references

cites work

Brd4 shields chromatin from ATM kinase signaling storms

1 reference

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Papillomaviruses use recombination-dependent replication to vegetatively amplify their genomes in differentiated cells

8 July 2018

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The bromodomain protein Brd4 insulates chromatin from DNA damage signalling

8 July 2018

1 reference

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Current understanding of the role of the Brd4 protein in the papillomavirus lifecycle

8 July 2018

1 reference

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The JAK-STAT transcriptional regulator, STAT-5, activates the ATM DNA damage pathway to induce HPV 31 genome amplification upon epithelial differentiation

8 July 2018

1 reference

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Recruitment of Brd4 to the human papillomavirus type 16 DNA replication complex is essential for replication of viral DNA.

8 July 2018

1 reference

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Phospho switch triggers Brd4 chromatin binding and activator recruitment for gene-specific targeting

8 July 2018

1 reference

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Bromodomain protein Brd4 plays a key role in Merkel cell polyomavirus DNA replication

8 July 2018

1 reference

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Engagement of the ATR-dependent DNA damage response at the human papillomavirus 18 replication centers during the initial amplification

8 July 2018

1 reference

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The Papillomavirus Episteme: a central resource for papillomavirus sequence data and analysis

8 July 2018

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Large scale genotype comparison of human papillomavirus E2-host interaction networks provides new insights for e2 molecular functions

8 July 2018

1 reference

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Human papillomaviruses recruit cellular DNA repair and homologous recombination factors to viral replication centers

8 July 2018

1 reference

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Gene bookmarking accelerates the kinetics of post-mitotic transcriptional re-activation

8 July 2018

1 reference

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The papillomavirus E1 helicase activates a cellular DNA damage response in viral replication foci

8 July 2018

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Nuclear accumulation of the papillomavirus E1 helicase blocks S-phase progression and triggers an ATM-dependent DNA damage response

8 July 2018

1 reference

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The Brd4 extraterminal domain confers transcription activation independent of pTEFb by recruiting multiple proteins, including NSD3.

8 July 2018

1 reference

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Nucleotide deficiency promotes genomic instability in early stages of cancer development

8 July 2018

1 reference

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Human papillomavirus (HPV) E7 induces prolonged G2 following S phase reentry in differentiated human keratinocytes

8 July 2018

1 reference

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Cell-type-specific replication initiation programs set fragility of the FRA3B fragile site

8 July 2018

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Suppression of inflammation by a synthetic histone mimic

8 July 2018

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Selective inhibition of BET bromodomains

8 July 2018

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Nuclear export of human papillomavirus type 31 E1 is regulated by Cdk2 phosphorylation and required for viral genome maintenance

8 July 2018

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Human keratinocytes are efficiently immortalized by a Rho kinase inhibitor

8 July 2018

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Genome-wide siRNA screen identifies SMCX, EP400, and Brd4 as E2-dependent regulators of human papillomavirus oncogene expression

8 July 2018

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Acetylation goes global: the emergence of acetylation biology.

8 July 2018

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Human papillomaviruses activate the ATM DNA damage pathway for viral genome amplification upon differentiation

8 July 2018

1 reference

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Viral manipulation of DNA repair and cell cycle checkpoints

8 July 2018

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8 July 2018

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Papillomavirus E2 proteins and the host BRD4 protein associate with transcriptionally active cellular chromatin

8 July 2018

1 reference

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Chromatin adaptor Brd4 modulates E2 transcription activity and protein stability

8 July 2018

1 reference

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Human papillomaviruses activate caspases upon epithelial differentiation to induce viral genome amplification

8 July 2018

1 reference

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Brd4-independent transcriptional repression function of the papillomavirus e2 proteins

8 July 2018

1 reference

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The double bromodomain-containing chromatin adaptor Brd4 and transcriptional regulation

8 July 2018

1 reference

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Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome

8 July 2018

1 reference

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Structure of the papillomavirus DNA-tethering complex E2:Brd4 and a peptide that ablates HPV chromosomal association

8 July 2018

1 reference

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Amino acid substitutions that specifically impair the transcriptional activity of papillomavirus E2 affect binding to the long isoform of Brd4

8 July 2018

1 reference

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Brd4 is required for e2-mediated transcriptional activation but not genome partitioning of all papillomaviruses

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836737

Brd4 links chromatin targeting to HPV transcriptional silencing

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836737

Enhanced histone acetylation and transcription: a dynamic perspective

8 July 2018

1 reference

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Partitioning viral genomes in mitosis: same idea, different targets

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836737

Bromodomain protein 4 mediates the papillomavirus E2 transcriptional activation function

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836737

Brd4 is involved in multiple processes of the bovine papillomavirus type 1 life cycle.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836737

Variations in the association of papillomavirus E2 proteins with mitotic chromosomes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836737

Human papillomavirus type 16 E1circumflexE4 contributes to multiple facets of the papillomavirus life cycle

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836737

Interaction of bovine papillomavirus E2 protein with Brd4 stabilizes its association with chromatin

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836737

The mitotic chromosome binding activity of the papillomavirus E2 protein correlates with interaction with the cellular chromosomal protein, Brd4.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836737

The X-ray structure of the papillomavirus helicase in complex with its molecular matchmaker E2.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836737

Interaction of the bovine papillomavirus E2 protein with Brd4 tethers the viral DNA to host mitotic chromosomes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836737

Roles of the E6 and E7 proteins in the life cycle of low-risk human papillomavirus type 11.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836737

The double bromodomain protein Brd4 binds to acetylated chromatin during interphase and mitosis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836737

Optimization of biotinyl-tyramide-based in situ hybridization for sensitive background-free applications on formalin-fixed, paraffin-embedded tissue specimens

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836737

Genetic analysis of high-risk e6 in episomal maintenance of human papillomavirus genomes in primary human keratinocytes.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836737

A Mammalian bromodomain protein, brd4, interacts with replication factor C and inhibits progression to S phase

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836737

Human papillomavirus type 31 oncoproteins E6 and E7 are required for the maintenance of episomes during the viral life cycle in normal human keratinocytes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836737

Long-term episomal maintenance of bovine papillomavirus type 1 plasmids is determined by attachment to host chromosomes, which Is mediated by the viral E2 protein and its binding sites

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836737

Transactivation by the E2 protein of oncogenic human papillomavirus type 31 is not essential for early and late viral functions

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836737

Activation of papillomavirus late gene transcription and genome amplification upon differentiation in semisolid medium is coincident with expression of involucrin and transglutaminase but not keratin-10.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836737

Evidence for a switch in the mode of human papillomavirus type 16 DNA replication during the viral life cycle

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836737

Transcriptional and replicational activation functions in the bovine papillomavirus type 1 E2 protein are encoded by different structural determinants.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836737

Targeted mutagenesis of the human papillomavirus type 16 E2 transactivation domain reveals separable transcriptional activation and DNA replication functions

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836737

Integration of human papillomavirus type 16 into the human genome correlates with a selective growth advantage of cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836737

Suppression of cellular proliferation by the papillomavirus E2 protein

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836737

A new type of papillomavirus DNA, its presence in genital cancer biopsies and in cell lines derived from cervical cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836737

The BPV1-E2 trans-acting protein can be either an activator or a repressor of the HPV18 regulatory region

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836737

Amplification of human papillomavirus genomes in vitro is dependent on epithelial differentiation.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836737

Viral integration and fragile sites in human papillomavirus-immortalized human keratinocyte cell lines

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836737

Evidence that the transcriptional trans-activating function of the bovine papillomavirus type 1 E2 gene is not required for viral DNA amplification in division-arrested cells.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836737

Differentiation-induced and constitutive transcription of human papillomavirus type 31b in cell lines containing viral episomes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836737

Transient replication of human papillomavirus DNAs

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836737

Biosynthesis of human papillomavirus from a continuous cell line upon epithelial differentiation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836737

10.1371/JOURNAL.PPAT.1003777

8 July 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24278023%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24278023%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

PubMed publication ID

24278023

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24278023%20AND%20SRC:MED&resulttype=core&format=json