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Mitochondrial fission and fusion factors reciprocally orchestrate mitophagic culling in mouse hearts and cultured fibroblasts
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Europe PubMed Central
PMC publication ID
4318753
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25600785%20AND%20SRC:MED&resulttype=core&format=json
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28 February 2020
title
Mitochondrial fission and fusion factors reciprocally orchestrate mitophagic culling in mouse hearts and cultured fibroblasts
(English)
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Europe PubMed Central
PMC publication ID
4318753
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25600785%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 February 2020
main subject
mitochondrial fission
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author
Luca Scorrano
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4
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Europe PubMed Central
PMC publication ID
4318753
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25600785%20AND%20SRC:MED&resulttype=core&format=json
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28 February 2020
author name string
Moshi Song
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1
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PMC publication ID
4318753
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25600785%20AND%20SRC:MED&resulttype=core&format=json
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28 February 2020
Katsuyoshi Mihara
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2
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PMC publication ID
4318753
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25600785%20AND%20SRC:MED&resulttype=core&format=json
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28 February 2020
Yun Chen
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3
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4318753
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25600785%20AND%20SRC:MED&resulttype=core&format=json
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28 February 2020
Gerald W Dorn
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5
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PMC publication ID
4318753
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25600785%20AND%20SRC:MED&resulttype=core&format=json
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28 February 2020
publication date
15 January 2015
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4318753
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retrieved
28 February 2020
published in
Cell Metabolism
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4318753
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28 February 2020
volume
21
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25600785%20AND%20SRC:MED&resulttype=core&format=json
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28 February 2020
issue
2
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Europe PubMed Central
PMC publication ID
4318753
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25600785%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 February 2020
page(s)
273-286
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4318753
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25600785%20AND%20SRC:MED&resulttype=core&format=json
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28 February 2020
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Parkin-independent mitophagy requires Drp1 and maintains the integrity of mammalian heart and brain
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PubMed Central
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Super-suppression of mitochondrial reactive oxygen species signaling impairs compensatory autophagy in primary mitophagic cardiomyopathy
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Mitochondrial contagion induced by Parkin deficiency in Drosophila hearts and its containment by suppressing mitofusin
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Acute inhibition of excessive mitochondrial fission after myocardial infarction prevents long-term cardiac dysfunction
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Bit-by-bit autophagic removal of parkin-labelled mitochondria
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Mitochondrial genome linearization is a causative factor for cardiomyopathy in mice and Drosophila.
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Inhibition of Drp1-dependent mitochondrial division impairs myogenic differentiation.
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8 July 2018
PINK1-phosphorylated mitofusin 2 is a Parkin receptor for culling damaged mitochondria
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Mitochondrial dynamism and cardiac fate--a personal perspective
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Mitochondrial fragmentation caused by phenanthroline promotes mitophagy
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Mitochondrial fission, fusion, and stress
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PubMed Central
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8 July 2018
Mitofusins 1 and 2 are essential for postnatal metabolic remodeling in heart
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Mitofusin 2-containing mitochondrial-reticular microdomains direct rapid cardiomyocyte bioenergetic responses via interorganelle Ca(2+) crosstalk
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Bax regulates primary necrosis through mitochondrial dynamics
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Mitochondrial dynamics in heart disease
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8 July 2018
Mitochondrial fusion is essential for organelle function and cardiac homeostasis
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PubMed Central
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8 July 2018
Tubular network formation protects mitochondria from autophagosomal degradation during nutrient starvation
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8 July 2018
p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both
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8 July 2018
Inhibiting mitochondrial fission protects the heart against ischemia/reperfusion injury
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Dual autonomous mitochondrial cell death pathways are activated by Nix/BNip3L and induce cardiomyopathy
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Cyclophilin D is required for mitochondrial removal by autophagy in cardiac cells
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PINK1 is selectively stabilized on impaired mitochondria to activate Parkin
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PubMed Central
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8 July 2018
Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice
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Calcium elevation in mitochondria is the main Ca2+ requirement for mitochondrial permeability transition pore (mPTP) opening.
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Fission and selective fusion govern mitochondrial segregation and elimination by autophagy
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Nix-mediated apoptosis links myocardial fibrosis, cardiac remodeling, and hypertrophy decompensation
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8 July 2018
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Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death
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8 July 2018
Drp-1-dependent division of the mitochondrial network blocks intraorganellar Ca2+ waves and protects against Ca2+-mediated apoptosis
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8 July 2018
Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development
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Mitochondrial evolution
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8 July 2018
In situ detection of fragmented dna (tunel assay) fails to discriminate among apoptosis, necrosis, and autolytic cell death: A cautionary note
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Altered skeletal muscle mitochondrial biogenesis but improved endurance capacity in trained OPA1-deficient mice
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25 October 2018
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Temporally regulated and tissue-specific gene manipulations in the adult and embryonic heart using a tamoxifen-inducible Cre protein
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25 October 2018
In situ detection of fragmented DNA (TUNEL assay) fails to discriminate among apoptosis, necrosis, and autolytic cell death: a cautionary note
1 reference
stated in
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reference URL
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25 October 2018
Mitophagy is triggered by mild oxidative stress in a mitochondrial fission dependent manner
1 reference
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PubMed Central
reference URL
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1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25600785
retrieved
12 December 2020
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Identifiers
DOI
10.1016/J.CMET.2014.12.011
1 reference
stated in
Europe PubMed Central
PMC publication ID
4318753
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25600785%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 February 2020
PMC publication ID
4318753
1 reference
stated in
Europe PubMed Central
PMC publication ID
4318753
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25600785%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 February 2020
PubMed publication ID
25600785
1 reference
stated in
Europe PubMed Central
PMC publication ID
4318753
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25600785%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 February 2020
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