(Q35054730)

25557293

6 August 2017

title

Disulfiram-induced cytotoxicity and endo-lysosomal sequestration of zinc in breast cancer cells (English)

1 reference

6 August 2017

1 reference

ChEBI release 2020-05-28

1 reference

ChEBI release 2020-05-28

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25557293%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Arwyn T. Jones

7

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13 June 2020

author name string

Helen L Wiggins

1

1 reference

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13 June 2020

Jennifer M Wymant

2

1 reference

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13 June 2020

Francesca Solfa

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25557293%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Stephen E Hiscox

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25557293%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Andrew D Westwell

6

1 reference

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13 June 2020

language of work or name

English

0 references

publication date

31 December 2014

1 reference

25557293

6 August 2017

published in

Biochemical Pharmacology

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25557293%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

volume

93

1 reference

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13 June 2020

issue

3

1 reference

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13 June 2020

page(s)

332-342

1 reference

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describes a project that uses

13 June 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4318799/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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8 July 2018

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8 July 2018

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8 July 2018

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LAMTOR1 depletion induces p53-dependent apoptosis via aberrant lysosomal activation

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Disulfiram modulated ROS-MAPK and NFκB pathways and targeted breast cancer cells with cancer stem cell-like properties

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Zinc(II) ion mediates tamoxifen-induced autophagy and cell death in MCF-7 breast cancer cell line

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Exploring the structural requirements for inhibition of the ubiquitin E3 ligase breast cancer associated protein 2 (BCA2) as a treatment for breast cancer.

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Disulfiram/copper complex inhibiting NFkappaB activity and potentiating cytotoxic effect of gemcitabine on colon and breast cancer cell lines.

8 July 2018

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The important role of the apoptotic effects of zinc in the development of cancers

8 July 2018

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Ni(II), Cu(II), and Zn(II) diethyldithiocarbamate complexes show various activities against the proteasome in breast cancer cells.

8 July 2018

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8 July 2018

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ZIP7-mediated intracellular zinc transport contributes to aberrant growth factor signaling in antihormone-resistant breast cancer Cells.

8 July 2018

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Disulfiram promotes the conversion of carcinogenic cadmium to a proteasome inhibitor with pro-apoptotic activity in human cancer cells.

8 July 2018

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Diverse effects of zinc on NF-kappaB and AP-1 transcription factors: implications for prostate cancer progression

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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Disulfiram, a clinically used anti-alcoholism drug and copper-binding agent, induces apoptotic cell death in breast cancer cultures and xenografts via inhibition of the proteasome activity

25 October 2018

1 reference

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N,N-diethyldithiocarbamate produces copper accumulation, lipid peroxidation, and myelin injury in rat peripheral nerve

25 October 2018

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Inhibition of Invasion and Angiogenesis by Zinc-Chelating Agent Disulfiram

25 October 2018

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Cu/Zn superoxide dismutase plays a role in angiogenesis

25 October 2018

1 reference

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25 October 2018

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Comparison between concentrations of trace elements in normal and neoplastic human breast tissue

25 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25557293

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Rapid degradation of disulfiram by serum albumin

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25557293

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.BCP.2014.12.014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25557293%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25557293%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

25557293

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25557293%20AND%20SRC:MED&resulttype=core&format=json