(Q35055652)

6 August 2017

title

Neurotrophin signaling via TrkB and TrkC receptors promotes the growth of brain tumor-initiating cells (English)

1 reference

6 August 2017

Samuel Lawn

1

1 reference

6 August 2017

Niveditha Krishna

2

1 reference

6 August 2017

Alexandra Pisklakova

3

1 reference

6 August 2017

Xiaotao Qu

4

1 reference

6 August 2017

David A Fenstermacher

5

1 reference

6 August 2017

Michelle Fournier

6

1 reference

6 August 2017

Frank D Vrionis

7

1 reference

6 August 2017

Nam Tran

8

1 reference

6 August 2017

Jennifer A Chan

9

1 reference

6 August 2017

Rajappa S Kenchappa

10

1 reference

6 August 2017

Peter A Forsyth

11

1 reference

6 August 2017

language of work or name

English

0 references

publication date

23 December 2014

1 reference

Journal of Biological Chemistry

6 August 2017

published in

1 reference

6 August 2017

volume

290

1 reference

6 August 2017

issue

6

1 reference

6 August 2017

page(s)

3814-3824

1 reference

The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma

6 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4319045

p75 neurotrophin receptor cleavage by α- and γ-secretases is required for neurotrophin-mediated proliferation of brain tumor-initiating cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4319045

The integrated landscape of driver genomic alterations in glioblastoma

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4319045

Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4319045

The crystal structures of TrkA and TrkB suggest key regions for achieving selective inhibition

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4319045

A restricted cell population propagates glioblastoma growth after chemotherapy

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4319045

Identification of a low-molecular weight TrkB antagonist with anxiolytic and antidepressant activity in mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4319045

Pathway analysis of glioblastoma tissue after preoperative treatment with the EGFR tyrosine kinase inhibitor gefitinib--a phase II trial

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4319045

Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4319045

On Trk--the TrkB signal transduction pathway is an increasingly important target in cancer biology

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4319045

Targeted inhibition of the Hedgehog pathway in established malignant glioma xenografts enhances survival

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4319045

Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4319045

Inhibition of Akt inhibits growth of glioblastoma and glioblastoma stem-like cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4319045

Phase II study of erlotinib plus temozolomide during and after radiation therapy in patients with newly diagnosed glioblastoma multiforme or gliosarcoma

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4319045

Gamma-secretase represents a therapeutic target for the treatment of invasive glioma mediated by the p75 neurotrophin receptor

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4319045

Deletion of TrkB in adult progenitors alters newborn neuron integration into hippocampal circuits and increases anxiety-like behavior

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4319045

Brain cancer stem cells display preferential sensitivity to Akt inhibition

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4319045

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4319045

TrkB regulates hippocampal neurogenesis and governs sensitivity to antidepressive treatment

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4319045

Neurotrophin receptors expression and JNK pathway activation in human astrocytomas.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4319045

Coactivation of receptor tyrosine kinases affects the response of tumor cells to targeted therapies

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4319045

The p75 neurotrophin receptor is a central regulator of glioma invasion

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4319045

Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4319045

Neurotrophin-regulated signalling pathways

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4319045

Notch pathway inhibition depletes stem-like cells and blocks engraftment in embryonal brain tumors

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4319045

Identification of human brain tumour initiating cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4319045

Brain-metastatic melanoma: a neurotrophic perspective

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4319045

Neurotrophins and their receptors: a convergence point for many signalling pathways

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4319045

Trk receptor tyrosine kinases: a bridge between cancer and neural development

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4319045

The TrkB-Shc site signals neuronal survival and local axon growth via MEK and P13-kinase

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4319045

Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4319045

Nerve growth factor activates extracellular signal-regulated kinase and p38 mitogen-activated protein kinase pathways to stimulate CREB serine 133 phosphorylation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4319045

Coupling of the RAS-MAPK pathway to gene activation by RSK2, a growth factor-regulated CREB kinase

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4319045

Trk A, B, and C are commonly expressed in human astrocytes and astrocytic gliomas but not by human oligodendrocytes and oligodendroglioma.

8 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.599373

Expression of the neurotrophin receptors Trk A and Trk B in adult human astrocytoma and glioblastoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.599373

Proliferation of human glioblastoma stem cells occurs independently of exogenous mitogens.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.599373

Disruption of NGF binding to the low affinity neurotrophin receptor p75LNTR reduces NGF binding to TrkA on PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.599373

Cellular assays for high-throughput screening for modulators of Trk receptor tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.599373

Mediation by a CREB family transcription factor of NGF-dependent survival of sympathetic neurons

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25538243

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M114.599373

1 reference

release_rsk2hcsgbfb2tjm2irrilutqsi

6 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/rsk2hcsgbfb2tjm2irrilutqsi

mapped directly with Wikidata item

24 November 2022

based on heuristic

PMC publication ID

4319045

1 reference

6 August 2017

1 reference