(Q35059259)

English

Critical modifier role of membrane-cystic fibrosis transmembrane conductance regulator-dependent ceramide signaling in lung injury and emphysema

scientific article

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scholarly article

1 reference

Europe PubMed Central

6 August 2017

Critical modifier role of membrane-cystic fibrosis transmembrane conductance regulator-dependent ceramide signaling in lung injury and emphysema (English)

1 reference

Europe PubMed Central

6 August 2017

cystic fibrosis

0 references

transmembrane protein

0 references

1 reference

based on heuristic

inferred from title

pulmonary emphysema

1 reference

based on heuristic

inferred from title

pulmonary injury

1 reference

based on heuristic

inferred from title

author name string

Manish Bodas

1

1 reference

Europe PubMed Central

6 August 2017

Taehong Min

2

1 reference

Europe PubMed Central

6 August 2017

Steven Mazur

3

1 reference

Europe PubMed Central

6 August 2017

Neeraj Vij

4

1 reference

Europe PubMed Central

6 August 2017

language of work or name

0 references

publication date

6 December 2010

1 reference

Europe PubMed Central

6 August 2017

Journal of Immunology

1 reference

Europe PubMed Central

6 August 2017

186

1 reference

Europe PubMed Central

6 August 2017

1

1 reference

Europe PubMed Central

6 August 2017

602-613

1 reference

Europe PubMed Central

6 August 2017

Expression of wild-type CFTR suppresses NF-kappaB-driven inflammatory signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119853

8 July 2018

Proinflammatory phenotype and increased caveolin-1 in alveolar macrophages with silenced CFTR mRNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119853

8 July 2018

The NF-kappaB signaling in cystic fibrosis lung disease: pathophysiology and therapeutic potential

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119853

8 July 2018

T cell pathways involving CTLA4 contribute to a model of acute lung injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119853

8 July 2018

Macrophages and dendritic cells express tight junction proteins and exchange particles in an in vitro model of the human airway wall.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119853

8 July 2018

Protein processing and inflammatory signaling in Cystic Fibrosis: challenges and therapeutic strategies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119853

8 July 2018

CFTR-mediated halide transport in phagosomes of human neutrophils

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119853

8 July 2018

The antioxidant role of thiocyanate in the pathogenesis of cystic fibrosis and other inflammation-related diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119853

8 July 2018

CFTR and tight junctions in cultured bronchial epithelial cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119853

8 July 2018

CD4+CD25+Foxp3+ Tregs resolve experimental lung injury in mice and are present in humans with acute lung injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119853

8 July 2018

Characteristics of Cl- uptake in rat alveolar type I cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119853

8 July 2018

Naturally occurring and inducible T-regulatory cells modulating immune response in allergic asthma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119853

8 July 2018

Neutral sphingomyelinase 2 is activated by cigarette smoke to augment ceramide-induced apoptosis in lung cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119853

8 July 2018

CFTR is a negative regulator of NFkappaB mediated innate immune response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119853

8 July 2018

Defective CFTR increases synthesis and mass of sphingolipids that modulate membrane composition and lipid signaling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119853

8 July 2018

Neutrophils in cystic fibrosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119853

8 July 2018

The isolation and characterization of murine macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119853

8 July 2018

Ceramide-enriched membrane domains--structure and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119853

8 July 2018

The unexpected role of acid sphingomyelinase in cell death and the pathophysiology of common diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119853

8 July 2018

Airway epithelial cell inflammatory signalling in cystic fibrosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119853

8 July 2018

Ceramide accumulation mediates inflammation, cell death and infection susceptibility in cystic fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119853

8 July 2018

CFTR in a lipid raft-TNFR1 complex modulates gap junctional intercellular communication and IL-8 secretion.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119853

8 July 2018

Pediatric respiratory and systemic effects of chronic air pollution exposure: nose, lung, heart, and brain pathology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119853

8 July 2018

Ion transport in alveolar type I cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119853

8 July 2018

Pseudomonas aeruginosa chronic colonization in cystic fibrosis patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119853

8 July 2018

A new model of cystic fibrosis pathology: lack of transport of glutathione and its thiocyanate conjugates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119853

8 July 2018

CFTR Expression in human neutrophils and the phagolysosomal chlorination defect in cystic fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119853

8 July 2018

Genetic adaptation by Pseudomonas aeruginosa to the airways of cystic fibrosis patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119853

8 July 2018

Infections and asthma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119853

8 July 2018

Response to acute lung infection with mucoid Pseudomonas aeruginosa in cystic fibrosis mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119853

8 July 2018

Asthma and COPD in cystic fibrosis intron-8 5T carriers. A population-based study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119853

8 July 2018

Infection and inflammation in cystic fibrosis: a short review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119853

8 July 2018

The role of airway epithelium and blood neutrophils in the inflammatory response in cystic fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119853

8 July 2018

Common and unique gene expression signatures of human macrophages in response to four strains of Mycobacterium avium that differ in their growth and persistence characteristics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119853

8 July 2018

Ceramide upregulation causes pulmonary cell apoptosis and emphysema-like disease in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119853

8 July 2018

Localization of cystic fibrosis transmembrane conductance regulator to lipid rafts of epithelial cells is required for Pseudomonas aeruginosa-induced cellular activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119853

8 July 2018

Exacerbations of chronic obstructive pulmonary disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119853

8 July 2018

CFTR is a pattern recognition molecule that extracts Pseudomonas aeruginosa LPS from the outer membrane into epithelial cells and activates NF-kappa B translocation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119853

8 July 2018

Lung infections associated with cystic fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119853

8 July 2018

Cystic fibrosis transmembrane regulator regulates uptake of sphingoid base phosphates and lysophosphatidic acid: modulation of cellular activity of sphingosine 1-phosphate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119853

8 July 2018

Tight junction, a platform for trafficking and signaling protein complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119853

8 July 2018

Inflammation and infection in naive human cystic fibrosis airway grafts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119853

8 July 2018

The PDZ-interacting domain of cystic fibrosis transmembrane conductance regulator is required for functional expression in the apical plasma membrane

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119853

8 July 2018

A PDZ-interacting domain in CFTR is an apical membrane polarization signal

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119853

8 July 2018

DeltaF508 heterozygosity in cystic fibrosis and susceptibility to asthma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119853

8 July 2018

Pathogenic mechanisms of chronic Pseudomonas aeruginosa infections in cystic fibrosis patients.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119853

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119853

8 July 2018

Alterations in ceramide concentration and pH determine the release of reactive oxygen species by Cftr-deficient macrophages on infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119853

27 September 2018

Therapeutic efficacy and safety of amitriptyline in patients with cystic fibrosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119853

27 September 2018

Depletion of natural CD4+CD25+ T regulatory cells with anti-CD25 antibody does not change the course of Pseudomonas aeruginosa-induced acute lung infection in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119853

27 September 2018

Increased T-regulatory cells within lymphocyte follicles in moderate COPD.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119853

27 September 2018

Macrophages directly contribute to the exaggerated inflammatory response in cystic fibrosis transmembrane conductance regulator-/- mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119853

27 September 2018

Sphingolipids in the lungs.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119853

27 September 2018

Pseudomonas aeruginosa in chronic obstructive pulmonary disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119853

27 September 2018

Ceramide: a key signaling molecule in a Guinea pig model of allergic asthmatic response and airway inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119853

27 September 2018

Cystic fibrosis transmembrane conductance regulator function is suppressed in cigarette smokers.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119853

27 September 2018

Inflammatory arthritis requires Foxo3a to prevent Fas ligand-induced neutrophil apoptosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119853

27 September 2018

Inhibition of chloride secretion in human bronchial epithelial cells by cigarette smoke extract

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119853

27 September 2018

Lumican regulates corneal inflammatory responses by modulating Fas-Fas ligand signaling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119853

27 September 2018

PAF-mediated pulmonary edema: a new role for acid sphingomyelinase and ceramide.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119853

27 September 2018

Delivery of CFTR by adenoviral vector to cystic fibrosis mouse lung in a model of chronicPseudomonas aeruginosalung infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119853

27 September 2018

Inflammatory response in airway epithelial cells isolated from patients with cystic fibrosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119853

27 September 2018

CD4-Regulatory Cells in COPD Patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3119853

16 November 2018

CFTR regulates phagosome acidification in macrophages and alters bactericidal activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/21135173

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytokine dysregulation in activated cystic fibrosis (CF) peripheral lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/21135173

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CFTR gene mutations--including three novel nucleotide substitutions--and haplotype background in patients with asthma, disseminated bronchiectasis and chronic obstructive pulmonary disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/21135173

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative aspects of lung pathology in cystic fibrosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21135173

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early pulmonary inflammation in infants with cystic fibrosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21135173

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nasal and bronchoalveolar lavage fluid cytokines in early cystic fibrosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21135173

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic risk factors for chronic obstructive pulmonary disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/21135173

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early inflammation in the airways of a cystic fibrosis foetus

1 reference

https://pubmed.ncbi.nlm.nih.gov/21135173

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.4049/JIMMUNOL.1002850

1 reference

Europe PubMed Central

6 August 2017

release_3mmknqysibakpg275igx47gm3m

1 reference

https://api.fatcat.wiki/v0/release/3mmknqysibakpg275igx47gm3m

24 November 2022

based on heuristic

mapped directly with Wikidata item

1 reference

Europe PubMed Central

6 August 2017

1 reference

Europe PubMed Central

6 August 2017

ResearchGate publication ID

0 references

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