(Q35065209)

6 August 2017

Alpha-synuclein populates both elongated and broken helix states on small unilamellar vesicles (English)

1 reference

6 August 2017

1 reference

Sowmya Bekshe Lokappa

series ordinal

1

1 reference

PubMed ID

21524999

6 August 2017

Tobias S Ulmer

series ordinal

2

1 reference

PubMed ID

21524999

6 August 2017

language of work or name

English

0 references

publication date

27 April 2011

1 reference

Journal of Biological Chemistry

6 August 2017

1 reference

6 August 2017

286

1 reference

6 August 2017

21450-21457

1 reference

6 August 2017

24

1 reference

The N-terminus of the intrinsically disordered protein α-synuclein triggers membrane binding and helix folding

6 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122204

Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122204

A Combinatorial NMR and EPR Approach for Evaluating the Structural Ensemble of Partially Folded Proteins

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122204

Tryptophan probes at the alpha-synuclein and membrane interface.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122204

The clustering and spatial arrangement of beta-sheet sequence, but not order, govern alpha-synuclein fibrillogenesis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122204

Multiple tight phospholipid-binding modes of alpha-synuclein revealed by solution NMR spectroscopy

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122204

Effect of pseudorepeat rearrangement on alpha-synuclein misfolding, vesicle binding, and micelle binding

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122204

Interplay of alpha-synuclein binding and conformational switching probed by single-molecule fluorescence.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122204

Alpha-synuclein binds large unilamellar vesicles as an extended helix

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122204

Structure of membrane-bound alpha-synuclein from site-directed spin labeling and computational refinement

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122204

Molecular anatomy of a trafficking organelle

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122204

Protein misfolding, functional amyloid, and human disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122204

Common mechanisms of amyloid oligomer pathogenesis in degenerative disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122204

A topological model of the interaction between alpha-synuclein and sodium dodecyl sulfate micelles.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122204

Structure and dynamics of micelle-bound human alpha-synuclein

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122204

The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122204

alpha-Synuclein locus triplication causes Parkinson's disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122204

Alzheimer's disease and Parkinson's disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122204

A broken alpha -helix in folded alpha -Synuclein

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122204

Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122204

Stabilization of alpha-synuclein secondary structure upon binding to synthetic membranes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122204

Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122204

Alpha-synuclein in Lewy bodies

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122204

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122204

NACP, a protein implicated in Alzheimer's disease and learning, is natively unfolded

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122204

Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122204

The precursor protein of non-A beta component of Alzheimer's disease amyloid is a presynaptic protein of the central nervous system

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122204

Characterization of a novel protein regulated during the critical period for song learning in the zebra finch.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122204

Interaction of an apolipoprotein (apoLP-alanine) with phosphatidylcholine.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122204

A probability concept about size distributions of sonicated lipid vesicles.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122204

Calculation of protein extinction coefficients from amino acid sequence data

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122204

Membrane insertion and lateral mobility of synthetic amphiphilic signal peptides in lipid model membranes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122204

Binding of alpha-synuclein to brain vesicles is abolished by familial Parkinson's disease mutation.

8 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.224055

Alpha-synuclein has a high affinity for packing defects in a bilayer membrane: a thermodynamics study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.224055

Membrane-bound alpha-synuclein forms an extended helix: long-distance pulsed ESR measurements using vesicles, bicelles, and rodlike micelles

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.224055

Conformational properties of alpha-synuclein in its free and lipid-associated states

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.224055

Broken helix in vesicle and micelle-bound alpha-synuclein: insights from site-directed spin labeling-EPR experiments and MD simulations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.224055

Comparison of structure and dynamics of micelle-bound human alpha-synuclein and Parkinson disease variants

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.224055

Phase behavior of large unilamellar vesicles composed of synthetic phospholipids

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.224055

A stable lipid-induced aggregate of alpha-synuclein

21 January 2018

1 reference

12 December 2020

Direct evidence of coexisting horseshoe and extended helix conformations of membrane-bound alpha-synuclein

1 reference

12 December 2020

Diffusion of univalent ions across the lamellae of swollen phospholipids

1 reference

12 December 2020

Studies on phosphatidylcholine vesicles. Formation and physical characteristics

1 reference

12 December 2020

Computed circular dichroism spectra for the evaluation of protein conformation

1 reference

12 December 2020

Morphology of gel state phosphatidylethanolamine and phosphatidylcholine liposomes: a negative stain electron microscopic study

1 reference

12 December 2020

Theoretical CD studies of polypeptide helices: examination of important electronic and geometric factors

1 reference

12 December 2020

The core Alzheimer's peptide NAC forms amyloid fibrils which seed and are seeded by beta-amyloid: is NAC a common trigger or target in neurodegenerative disease?

1 reference

12 December 2020

Antiparallel arrangement of the helices of vesicle-bound alpha-synuclein

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M111.224055

1 reference

6 August 2017

1 reference

6 August 2017

1 reference

PubMed ID

21524999