(Q35065301)

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Protein kinase A activity at the endoplasmic reticulum surface is responsible for augmentation of human ether-a-go-go-related gene product (HERG).

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scholarly article

1 reference

Europe PubMed Central

6 August 2017

Protein kinase A activity at the endoplasmic reticulum surface is responsible for augmentation of human ether-a-go-go-related gene product (HERG). (English)

1 reference

Europe PubMed Central

6 August 2017

endoplasmic reticulum

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author name string

Jakub Sroubek

1

1 reference

Europe PubMed Central

6 August 2017

Thomas V McDonald

2

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Europe PubMed Central

6 August 2017

language of work or name

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publication date

2 May 2011

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Europe PubMed Central

6 August 2017

number of pages

10

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inferred from page(s)

Journal of Biological Chemistry

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Europe PubMed Central

6 August 2017

286

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Europe PubMed Central

6 August 2017

24

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Europe PubMed Central

6 August 2017

21927-21936

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Europe PubMed Central

6 August 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3122247/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Post-transcriptional control of human ether-a-go-go-related gene potassium channel protein by alpha-adrenergic receptor stimulation.

1 reference

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8 July 2018

Underpinning compartmentalised cAMP signalling through targeted cAMP breakdown

1 reference

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Translational control from head to tail

1 reference

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8 July 2018

PKA phosphorylation of HERG protein regulates the rate of channel synthesis.

1 reference

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8 July 2018

A-kinase anchoring protein targeting of protein kinase A and regulation of HERG channels

1 reference

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8 July 2018

Modulation of cardiac function by A-kinase anchoring proteins

1 reference

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beta-arrestin-biased agonism at the beta2-adrenergic receptor

1 reference

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beta2-adrenergic receptor signaling and desensitization elucidated by quantitative modeling of real time cAMP dynamics

1 reference

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Differential association between HERG and KCNE1 or KCNE2

1 reference

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8 July 2018

Heteromeric assembly of human ether-à-go-go-related gene (hERG) 1a/1b channels occurs cotranslationally via N-terminal interactions

1 reference

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8 July 2018

Compartmentalized cAMP/PKA signalling regulates cardiac excitation-contraction coupling

1 reference

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8 July 2018

Subcellular dynamics of protein kinase A activity visualized by FRET-based reporters

1 reference

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The long QT syndrome family of cardiac ion channelopathies: a HuGE review

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8 July 2018

Most LQT2 mutations reduce Kv11.1 (hERG) current by a class 2 (trafficking-deficient) mechanism

1 reference

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8 July 2018

Compartmentalization of adenylate cyclase and cAMP signalling

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Signal propagation from membrane messengers to nuclear effectors revealed by reporters of phosphoinositide dynamics and Akt activity

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Beta-adrenergic blockers in heart failure: review of mechanisms of action and clinical outcomes

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Regulation of mRNA translation by protein folding in the endoplasmic reticulum

1 reference

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Risk stratification in the long-QT syndrome.

1 reference

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8 July 2018

14-3-3 amplifies and prolongs adrenergic stimulation of HERG K+ channel activity

1 reference

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8 July 2018

A structural basis for drug-induced long QT syndrome

1 reference

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8 July 2018

Protein kinase C enhances the rapidly activating delayed rectifier potassium current, IKr, through a reduction in C-type inactivation in guinea-pig ventricular myocytes

1 reference

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8 July 2018

Arrhythmias in heart failure: current concepts of mechanisms and therapy

1 reference

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8 July 2018

Electrophysiological remodeling in hypertrophy and heart failure

1 reference

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8 July 2018

Correction of defective protein trafficking of a mutant HERG potassium channel in human long QT syndrome. Pharmacological and temperature effects

1 reference

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8 July 2018

cAMP induces co-translational modification of proteins in IPC-81 cells

1 reference

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8 July 2018

mAKAP: an A-kinase anchoring protein targeted to the nuclear membrane of differentiated myocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122247

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Effect of metoprolol CR/XL in chronic heart failure: Metoprolol CR/XL Randomised Intervention Trial in Congestive Heart Failure (MERIT-HF)

1 reference

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NH2-Terminal targeting motifs direct dual specificity A-kinase-anchoring protein 1 (D-AKAP1) to either mitochondria or endoplasmic reticulum

1 reference

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Mobility of cytochrome P450 in the endoplasmic reticulum membrane

1 reference

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HERG channel dysfunction in human long QT syndrome. Intracellular transport and functional defects

1 reference

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Quantitative fluorescence resonance energy transfer measurements using fluorescence microscopy

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The effect of carvedilol on morbidity and mortality in patients with chronic heart failure. U.S. Carvedilol Heart Failure Study Group

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1 reference

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1 reference

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A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel

1 reference

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1 reference

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Actin nascent chains are substrates for cyclic AMP-dependent phosphorylation in vivo

1 reference

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8 July 2018

The long QT syndrome: a prospective international study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122247

8 July 2018

Structural evidence for direct interaction between the molecular components of the transverse tubule/sarcoplasmic reticulum junction in skeletal muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122247

8 July 2018

Fluorescence ratio imaging of cyclic AMP in single cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122247

8 July 2018

Phosphorylation of a 22,000-dalton component of the cardiac sarcoplasmic reticulum by adenosine 3':5'-monophosphate-dependent protein kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122247

8 July 2018

Isoform-specific PKA dynamics revealed by dye-triggered aggregation and DAKAP1alpha-mediated localization in living cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122247

27 September 2018

C-terminal HERG (LQT2) mutations disrupt IKr channel regulation through 14-3-3epsilon.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122247

27 September 2018

A syntaxin 1, Galpha(o), and N-type calcium channel complex at a presynaptic nerve terminal: analysis by quantitative immunocolocalization.

1 reference

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27 September 2018

Discrete microdomains with high concentration of cAMP in stimulated rat neonatal cardiac myocytes

1 reference

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27 September 2018

When is cAMP not cAMP? Effects of compartmentalization.

1 reference

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27 September 2018

Deletion of protein kinase A phosphorylation sites in the HERG potassium channel inhibits activation shift by protein kinase A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122247

27 September 2018

Regulation of ion channels by cAMP-dependent protein kinase and A-kinase anchoring proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122247

27 September 2018

Distinct distribution of different Na+ pump alpha subunit isoforms in plasmalemma. Physiological implications.

1 reference

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27 September 2018

The dominant negative LQT2 mutation A561V reduces wild-type HERG expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/21536683

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclic AMP regulates the HERG K(+) channel by dual pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/21536683

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A 15-residue bifunctional element in D-AKAP1 is required for both endoplasmic reticulum and mitochondrial targeting

1 reference

https://pubmed.ncbi.nlm.nih.gov/21536683

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Primary structural determinants essential for potent inhibition of cAMP-dependent protein kinase by inhibitory peptides corresponding to the active portion of the heat-stable inhibitor protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/21536683

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isoproterenol antagonizes prolongation of refractory period by the class III antiarrhythmic agent E-4031 in guinea pig myocytes. Mechanism of action

1 reference

https://pubmed.ncbi.nlm.nih.gov/21536683

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular characterization of the stretch-induced adaptation of cultured cardiac cells. An in vitro model of load-induced cardiac hypertrophy

1 reference

https://pubmed.ncbi.nlm.nih.gov/21536683

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhanced susceptibility for acquired torsade de pointes arrhythmias in the dog with chronic, complete AV block is related to cardiac hypertrophy and electrical remodeling

1 reference

https://pubmed.ncbi.nlm.nih.gov/21536683

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M110.201699

1 reference

Europe PubMed Central

6 August 2017

1 reference

Europe PubMed Central

6 August 2017

1 reference

Europe PubMed Central

6 August 2017

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