(Q35066729)

6 August 2017

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title

Lead-induced endoplasmic reticulum (ER) stress responses in the nervous system (English)

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6 August 2017

endoplasmic reticulum

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author name string

Yongchang Qian

series ordinal

1

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PubMed ID

12587673

6 August 2017

Evelyn Tiffany-Castiglioni

series ordinal

2

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6 August 2017

1 January 2003

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6 August 2017

Neurochemical Research

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6 August 2017

28

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6 August 2017

1

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6 August 2017

153-162

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https://scigraph.springernature.com/pub.10.1023/a:1021664632393

6 August 2017

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cites work

Effect of lead exposure and accumulation on copper homeostasis in cultured C6 rat glioma cells.

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12 December 2020

Risk of nervous system cancer among workers exposed to lead

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12 December 2020

The human Nramp2 gene: characterization of the gene structure, alternative splicing, promoter region and polymorphisms

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12 December 2020

Mouse Lymphoma Cells Destined to Undergo Apoptosis in Response to Thapsigargin Treatment Fail to Generate a Calcium-mediatedgrp78/grp94Stress Response

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12 December 2020

Disruption of the zinc finger domain: a common target that underlies many of the effects of lead

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12 December 2020

Roles of lead-binding proteins in mediating lead bioavailability

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12 December 2020

Differential ability of astroglia and neuronal cells to accumulate lead: dependence on cell type and on degree of differentiation

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12 December 2020

The sarco/endoplasmic reticulum calcium-ATPase 2b is an endoplasmic reticulum stress-inducible protein

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12 December 2020

Inhibition of sarcoplasmic reticulum Ca(2+)-ATPase activity by cadmium, lead and mercury

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12 December 2020

Perturbations in maturation of secretory proteins and their association with endoplasmic reticulum chaperones in a cell culture model for epithelial ischemia

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12 December 2020

Conservation and divergence of the yeast and mammalian unfolded protein response. Activation of specific mammalian endoplasmic reticulum stress element of the grp78/BiP promoter by yeast Hac1.

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12 December 2020

Cellular uptake of lead is activated by depletion of intracellular calcium stores

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12 December 2020

Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response

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12 December 2020

Effects of weight loss and exercise on the distribution of lead and essential trace elements in rats with prior lead exposure

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12 December 2020

The endoribonuclease activity of mammalian IRE1 autoregulates its mRNA and is required for the unfolded protein response

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12 December 2020

Lead-protein interactions as a basis for lead toxicity

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12 December 2020

Alterations in calcium homeostasis on lead exposure in rat synaptosomes

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12 December 2020

Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response

1 reference

12 December 2020

Requirement of tyrosine- and serine/threonine kinases in the transcriptional activation of the mammalian grp78/BiP promoter by thapsigargin.

1 reference

12 December 2020

Occupational exposure to manganese, copper, lead, iron, mercury and zinc and the risk of Parkinson's disease.

1 reference

12 December 2020

Depletion of intracellular calcium stores by calcium ionophore A23187 induces the genes for glucose-regulated proteins in hamster fibroblasts

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12 December 2020

Regulation and developmental expression of the divalent metal-ion transporter in the rat brain

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12 December 2020

On the role of voltage-dependent calcium channels in calcium signaling of astrocytes in situ.

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12 December 2020

The unfolded protein response: an intracellular signalling pathway with many surprising features

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12 December 2020

Lead activates nuclear transcription factor-kappaB, activator protein-1, and amino-terminal c-Jun kinase in pheochromocytoma cells

1 reference

12 December 2020

Endoplasmic reticulum stress proteins block oxidant-induced Ca2+ increases and cell death.

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12 December 2020

Brefeldin A as a regulator of grp78 gene expression in mammalian cells

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12 December 2020

A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (Ire1p) in mammalian cells

1 reference

12 December 2020

Upregulation of BiP and CHOP by the unfolded-protein response is independent of presenilin expression.

1 reference

12 December 2020

Endoplasmic reticulum stress-induced formation of transcription factor complex ERSF including NF-Y (CBF) and activating transcription factors 6alpha and 6beta that activates the mammalian unfolded protein response

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12 December 2020

Interference of lead with the calcium release activated calcium flux of osteoblast-like cells

1 reference

12 December 2020

Identification of the cis-acting endoplasmic reticulum stress response element responsible for transcriptional induction of mammalian glucose-regulated proteins. Involvement of basic leucine zipper transcription factors

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12 December 2020

Molecular mechanisms of lead neurotoxicity

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12 December 2020

The genetic effects of environmental lead

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12 December 2020

Effects of lead treatment on intracellular iron and copper concentrations in cultured astroglia

1 reference

12 December 2020

XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor

1 reference

12 December 2020

Deficits in psychologic and classroom performance of children with elevated dentine lead levels

1 reference

12 December 2020

The glucose-regulated proteins (GRP78 and GRP94): functions, gene regulation, and applications

1 reference

12 December 2020

Analysis of Pb2+ entry into cultured astroglia

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12 December 2020

Exposure of astrocytes to hypoxia/reoxygenation enhances expression of glucose-regulated protein 78 facilitating astrocyte release of the neuroprotective cytokine interleukin 6

1 reference

12 December 2020

Changes in serial blood lead levels during pregnancy

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12 December 2020

The dynamic role of GRP78/BiP in the coordination of mRNA translation with protein processing

1 reference

12 December 2020

The distribution of radioactive lead (210pb) in the cerebellum of developing rats

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12 December 2020

Cloning of mammalian Ire1 reveals diversity in the ER stress responses

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12 December 2020

Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein

1 reference

12 December 2020

Effects of lead on viability and intracellular metal content of C6 rat glioma cells

1 reference

12 December 2020

Cell culture models for lead toxicity in neuronal and glial cells

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12 December 2020

X-Ray microanalytical studies of lead-implanted rat brains

1 reference

12 December 2020

Induction of 78 kD glucose-regulated protein (GRP78) expression and redox-regulated transcription factor activity by lead and mercury in C6 rat glioma cells

1 reference

12 December 2020

Lead and cancer--association or causation?

1 reference

12 December 2020

Dissociation of Kar2p/BiP from an ER sensory molecule, Ire1p, triggers the unfolded protein response in yeast

1 reference

12 December 2020

Interactions of liver Grp78 and Escherichia coli recombinant Grp78 with ATP: multiple species and disaggregation

1 reference

12 December 2020

Lead poisoning: a disease for the next millennium

1 reference

12 December 2020

Human retroviruses: their role in neoplasia and immunodeficiency

1 reference

12 December 2020

Transactivation of the grp78 promoter by Ca2+ depletion. A comparative analysis with A23187 and the endoplasmic reticulum Ca(2+)-ATPase inhibitor thapsigargin

1 reference

12 December 2020

Pregnancy increases mobilization of lead from maternal skeleton

1 reference

12 December 2020

Mammalian stress response: induction of the glucose-regulated protein family

1 reference

12 December 2020

Lead transport and binding by human erythrocytes in vitro

1 reference

12 December 2020

Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity

1 reference

12 December 2020

Toxicokinetics of Lead in Lactating and Nonlactating Mice

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12 December 2020

Effects of PS1 deficiency on membrane protein trafficking in neurons.

1 reference

12 December 2020

The presence of malfolded proteins in the endoplasmic reticulum signals the induction of glucose-regulated proteins

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12 December 2020

Nramp2 is mutated in the anemic Belgrade (b) rat: evidence of a role for Nramp2 in endosomal iron transport.

1 reference

12 December 2020

Permeability of the blood-brain barrier to lead.

1 reference

12 December 2020

A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain

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12 December 2020

Lead targets GRP78, a molecular chaperone, in C6 rat glioma cells

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12 December 2020

Interaction of lead and zinc in cultured astroglia.

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12 December 2020

The endoplasmic reticulum Ca2+ store: a view from the lumen

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12 December 2020

Transactivation of the grp78 promoter by malfolded proteins, glycosylation block, and calcium ionophore is mediated through a proximal region containing a CCAAT motif which interacts with CTF/NF-I

1 reference

12 December 2020

Intracellular signaling from the endoplasmic reticulum to the nucleus

1 reference

12 December 2020

Effect of lead on the erythrocyte (Ca2+,Mg2+)-ATPase activity. Calmodulin involvement

1 reference

12 December 2020

Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1

1 reference

12 December 2020

Inhibition of immunoglobulin folding and secretion by dominant negative BiP ATPase mutants

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12 December 2020

ATF6 activated by proteolysis binds in the presence of NF-Y (CBF) directly to the cis-acting element responsible for the mammalian unfolded protein response

1 reference

12 December 2020

Analysis of gene expression in homocysteine-injured vascular endothelial cells: demonstration of GRP78/BiP expression, cloning and characterization of a novel reducing agent-tunicamycin regulated gene

1 reference

12 December 2020

Disturbed activation of endoplasmic reticulum stress transducers by familial Alzheimer's disease-linked presenilin-1 mutations

1 reference

12 December 2020

Pb2(+)-induced secretion from bovine chromaffin cells: fura-2 as a probe for Pb2+.

1 reference

12 December 2020

ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs

1 reference

12 December 2020

Neuropsychological correlates of low-level lead exposure in school-age children: a prospective study

1 reference

12 December 2020

Lead metabolism in the normal human: stable isotope studies

1 reference

12 December 2020

Lead uptake in brain capillary endothelial cells: activation by calcium store depletion

1 reference

12 December 2020

Distribution of divalent metal transporter 1 and metal transport protein 1 in the normal and Belgrade rat.

1 reference

12 December 2020

Transcription factor ATF2 regulation by the JNK signal transduction pathway

1 reference

12 December 2020

Bcl-2 and Bcl-X(L) block thapsigargin-induced nitric oxide generation, c-Jun NH(2)-terminal kinase activity, and apoptosis

1 reference

12 December 2020

Bone: target and source of environmental pollutant exposure

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12 December 2020

Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls

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12 December 2020

Environmental lead exposure: a public health problem of global dimensions

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12 December 2020

The chaperone BiP/GRP78 binds to amyloid precursor protein and decreases Abeta40 and Abeta42 secretion.

1 reference

12 December 2020

Kinetic analysis of lead metabolism in healthy humans

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12 December 2020

Lead enters bovine adrenal medullary cells through calcium channels

1 reference

12 December 2020

The endoplasmic reticulum stress-responsive protein GRP78 protects neurons against excitotoxicity and apoptosis: suppression of oxidative stress and stabilization of calcium homeostasis.

1 reference

12 December 2020

Effects of lead on gene expression

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12 December 2020

hCTR1: a human gene for copper uptake identified by complementation in yeast

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12 December 2020

Maturation of resistance to lead encephalopathy: cellular and subcellular mechanisms.

1 reference

12 December 2020

IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response

1 reference

12 December 2020

Intracellular signal transduction pathways as targets for neurotoxicants

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12 December 2020

Effects of arsenic, cadmium, chromium, and lead on gene expression regulated by a battery of 13 different promoters in recombinant HepG2 cells

1 reference

12 December 2020

Cloning and characterization of a mammalian proton-coupled metal-ion transporter

1 reference

12 December 2020

A role for presenilin-1 in nuclear accumulation of Ire1 fragments and induction of the mammalian unfolded protein response

1 reference

12 December 2020

Selective vulnerability of the developing brain to lead.

1 reference

12 December 2020

The mammalian endoplasmic reticulum stress response element consists of an evolutionarily conserved tripartite structure and interacts with a novel stress-inducible complex

1 reference

12 December 2020

Dissociation of glucose-regulated protein Grp78 and Grp78-IgE Fc complexes by ATP.

1 reference

12 December 2020

Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress

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12 December 2020

A 22 bp cis-acting element is necessary and sufficient for the induction of the yeast KAR2 (BiP) gene by unfolded proteins

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12 December 2020

Activation of ATF6 and an ATF6 DNA binding site by the endoplasmic reticulum stress response.

1 reference

12 December 2020

Distribution of divalent metal transporter 1 and metal transport protein 1 in the normal and Belgrade rat

1 reference

12 December 2020

Identifiers

DOI

10.1023/A:1021664632393

1 reference

PubMed ID

12587673

Dimensions Publication ID

6 August 2017

0 references

1 reference

PubMed ID

12587673