(Q35069575)

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SL651498, a GABAA receptor agonist with subtype-selective efficacy, as a potential treatment for generalized anxiety disorder and muscle spasms.

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scholarly article

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Europe PubMed Central

PubMed publication ID

6 August 2017

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Europe PubMed Central

SL651498, a GABAA receptor agonist with subtype-selective efficacy, as a potential treatment for generalized anxiety disorder and muscle spasms (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741675&resulttype=core&format=json

12 May 2020

generalized anxiety disorder

1 reference

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author name string

Guy Griebel

1

1 reference

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PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741675&resulttype=core&format=json

12 May 2020

Ghislaine Perrault

2

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PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741675&resulttype=core&format=json

12 May 2020

Jacques Simiand

3

1 reference

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PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741675&resulttype=core&format=json

12 May 2020

Caroline Cohen

4

1 reference

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PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741675&resulttype=core&format=json

12 May 2020

Patrick Granger

5

1 reference

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PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741675&resulttype=core&format=json

12 May 2020

Henri Depoortere

6

1 reference

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PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741675&resulttype=core&format=json

12 May 2020

Dominique Françon

7

1 reference

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PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741675&resulttype=core&format=json

12 May 2020

Patrick Avenet

8

1 reference

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PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741675&resulttype=core&format=json

12 May 2020

Hans Schoemaker

9

1 reference

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PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741675&resulttype=core&format=json

12 May 2020

Yannick Evanno

10

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741675&resulttype=core&format=json

12 May 2020

Mireille Sevrin

11

1 reference

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PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741675&resulttype=core&format=json

12 May 2020

Pascal George

12

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PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741675&resulttype=core&format=json

12 May 2020

Bernard Scatton

13

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741675&resulttype=core&format=json

12 May 2020

language of work or name

1 reference

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publication date

1 January 2003

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Europe PubMed Central

PubMed publication ID

6 August 2017

CNS Neuroscience & Therapeutics

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741675&resulttype=core&format=json

12 May 2020

9

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741675&resulttype=core&format=json

12 May 2020

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741675&resulttype=core&format=json

12 May 2020

3-20

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741675&resulttype=core&format=json

12 May 2020

Discriminative stimulus effects of drugs acting at GABA(A) receptors: differential profiles and receptor selectivity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12595909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New evidence that the pharmacological effects of benzodiazepine receptor ligands can be associated with activities at different BZ (omega) receptor subtypes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12595909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Benzodiazepine actions mediated by specific gamma-aminobutyric acid(A) receptor subtypes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12595909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of the pharmacological properties of classical and novel BZ-omega receptor ligands.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12595909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sedative but not anxiolytic properties of benzodiazepines are mediated by the GABA(A) receptor alpha1 subtype.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12595909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta-CCT, a selective BZ-omega1 receptor antagonist, blocks the anti-anxiety but not the amnesic action of chlordiazepoxide in mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12595909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular and neuronal substrate for the selective attenuation of anxiety.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12595909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of action of the hypnotic zolpidem in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/12595909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Behavioural effects of novel benzodiazepine (omega) receptor agonists and partial agonists: increases in punished responding and antagonism of the pentylenetetrazole cue

1 reference

https://pubmed.ncbi.nlm.nih.gov/12595909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A model of 'antipredator' defense in Swiss-Webster mice: effects of benzodiazepine receptor ligands with different intrinsic activities

1 reference

https://pubmed.ncbi.nlm.nih.gov/12595909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Zolpidem, triazolam, and diazepam decrease distress vocalizations in mouse pups: differential antagonism by flumazenil and beta-Carboline-3-carboxylate-t-butyl ester (beta-CCt).

1 reference

https://pubmed.ncbi.nlm.nih.gov/12595909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

1 reference

https://pubmed.ncbi.nlm.nih.gov/12595909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diazepam-induced changes in sleep: role of the alpha 1 GABA(A) receptor subtype

1 reference

https://pubmed.ncbi.nlm.nih.gov/12595909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SL651498: an anxioselective compound with functional selectivity for alpha2- and alpha3-containing gamma-aminobutyric acid(A) (GABA(A)) receptors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12595909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A new benzodiazepine pharmacology.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12595909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bi-directional changes in the levels of messenger RNAs encoding gamma-aminobutyric acidA receptor alpha subunits after flurazepam treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/12595909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A note on a simple apparatus for detecting neurological deficit in rats and mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/12595909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular mechanisms of the partial allosteric modulatory effects of bretazenil at gamma-aminobutyric acid type A receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/12595909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lack of tolerance and physical dependence upon repeated treatment with the novel hypnotic zolpidem

1 reference

https://pubmed.ncbi.nlm.nih.gov/12595909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A rapid screening method for the assessment of benzodiazepine receptor-related physical dependence in mice. Evaluation of benzodiazepine-related agonists and partial agonists

1 reference

https://pubmed.ncbi.nlm.nih.gov/12595909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Object recognition memory in the rat: the role of the hippocampus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12595909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alcohol, the chloride ionophore and endogenous ligands for benzodiazepine receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/12595909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacological validation of a novel animal model of anticipatory anxiety in mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12595909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel anxiolytics that act as partial agonists at benzodiazepine receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/12595909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differences in pharmacological profiles of a new generation of benzodiazepine and non-benzodiazepine hypnotics

1 reference

https://pubmed.ncbi.nlm.nih.gov/12595909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specific benzodiazepine receptors in rat brain characterized by high-affinity (3H)diazepam binding

1 reference

https://pubmed.ncbi.nlm.nih.gov/12595909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional organization of the nociceptive withdrawal reflexes. I. Activation of hindlimb muscles in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/12595909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for an involvement of GABA in the mediation of the cerebellar cGMP decrease and the anticonvulsant action of diazepam

1 reference

https://pubmed.ncbi.nlm.nih.gov/12595909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Behavioural Validation of a Light/Dark Choice Procedure for Testing Anti-Anxiety Agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/12595909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Some evidence for amnesic-like effects of benzodiazepines in animals

1 reference

https://pubmed.ncbi.nlm.nih.gov/12595909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Validation of open:closed arm entries in an elevated plus-maze as a measure of anxiety in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/12595909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Zolpidem, a novel nonbenzodiazepine hypnotic. I. Neuropharmacological and behavioral effects

1 reference

https://pubmed.ncbi.nlm.nih.gov/12595909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of benzodiazepines on acquisition and performance: a critical assessment

1 reference

https://pubmed.ncbi.nlm.nih.gov/12595909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ro 16-6028: a novel anxiolytic acting as a partial agonist at the benzodiazepine receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/12595909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Benzodiazepines alter acquisition and retention of an inhibitory avoidance response in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/12595909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A simple and reliable conflict procedure for testing anti-anxiety agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/12595909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A method for the routine assessment of fore- and hindlimb grip strength of rats and mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/12595909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A new method for rapid screening of minor tranquillizers in mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12595909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Place navigation impaired in rats with hippocampal lesions

1 reference

https://pubmed.ncbi.nlm.nih.gov/12595909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Onset and offset of the diazepam stimulus complex.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12595909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Current benzodiazepine issues.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12595909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The elevated T-maze: a new animal model of anxiety and memory.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12595909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Repeated treatment with alpidem, a new anxiolytic, does not induce tolerance or physical dependence

1 reference

https://pubmed.ncbi.nlm.nih.gov/12595909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The pharmacological properties of Y-23684, a benzodiazepine receptor partial agonist

1 reference

https://pubmed.ncbi.nlm.nih.gov/12595909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recent developments in the behavioral pharmacology of benzodiazepine (omega) receptors: evidence for the functional significance of receptor subtypes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12595909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fear-potentiated startle: a neural and pharmacological analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12595909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differences in affinity and efficacy of benzodiazepine receptor ligands at recombinant gamma-aminobutyric acidA receptor subtypes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12595909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Imidazenil: a new partial positive allosteric modulator of gamma-aminobutyric acid (GABA) action at GABAA receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/12595909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of convulsant and anticonvulsant agents on level and metabolism of gamma-aminobutyric acid in mouse brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/12595909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The behavioural and neuronal effects of the chronic administration of benzodiazepine anxiolytic and hypnotic drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/12595909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of the pharmacological profiles of the hypnotic drugs, zaleplon and zolpidem

1 reference

https://pubmed.ncbi.nlm.nih.gov/12595909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spinal NK1 receptors contribute to the increased excitability of the nociceptive flexor reflex during persistent peripheral inflammation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12595909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Benzodiazepine receptor: demonstration in the central nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/12595909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synapse-specific localization of NMDA and GABA(A) receptor subunits revealed by antigen-retrieval immunohistochemistry.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12595909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Theoretical and methodological considerations on drug discrimination learning

1 reference

https://pubmed.ncbi.nlm.nih.gov/12595909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

International Union of Pharmacology. XV. Subtypes of gamma-aminobutyric acidA receptors: classification on the basis of subunit structure and receptor function

1 reference

https://pubmed.ncbi.nlm.nih.gov/12595909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1527-3458.2003.TB00241.X

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741675&resulttype=core&format=json

12 May 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741675&resulttype=core&format=json

12 May 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741675&resulttype=core&format=json

12 May 2020

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