(Q35069580)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12595910%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

review article

1 reference

title

Dehydroepiandrosterone (DHEA) and the aging brain: flipping a coin in the "fountain of youth" (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12595910%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

1 reference

Marco Racchi

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12595910%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

Carla Balduzzi

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12595910%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

Emanuela Corsini

series ordinal

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12595910%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

publication date

1 January 2003

1 reference

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CNS Neuroscience & Therapeutics

31 October 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12595910%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

volume

9

1 reference

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31 October 2019

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12595910%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

page(s)

21-40

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12595910%20AND%20SRC:MED&resulttype=core&format=json

Neurosteroids: expression of steroidogenic enzymes and regulation of steroid biosynthesis in the central nervous system.

31 October 2019

cites work

1 reference

12 December 2020

Dehydroepiandrosterone antagonizes the neurotoxic effects of corticosterone and translocation of stress-activated protein kinase 3 in hippocampal primary cultures

1 reference

12 December 2020

Pregnenolone, pregnenolone sulfate, and cytochrome P450 side-chain cleavage enzyme in the amphibian brain and their seasonal changes.

1 reference

12 December 2020

Double-blind treatment of major depression with dehydroepiandrosterone

1 reference

12 December 2020

Localisation of dehydroepiandrosterone sulphotransferase in adult rat brain.

1 reference

12 December 2020

Neuropsychopharmacological properties of neuroactive steroids

1 reference

12 December 2020

Protein kinases: which one is the memory molecule?

1 reference

12 December 2020

Biotransformation of oral dehydroepiandrosterone in elderly men: significant increase in circulating estrogens.

1 reference

12 December 2020

Dehydroepiandrosterone treatment of midlife dysthymia.

1 reference

12 December 2020

Neurosteroidogenesis in astrocytes, oligodendrocytes, and neurons of cerebral cortex of rat brain

1 reference

12 December 2020

A defective protein kinase C anchoring system underlying age-associated impairment in TNF-alpha production in rat macrophages

1 reference

12 December 2020

Coordinated movement of RACK1 with activated betaIIPKC

1 reference

12 December 2020

Protein kinase C anchoring deficit in postmortem brains of Alzheimer's disease patients

1 reference

12 December 2020

Expression of cytochrome P450scc mRNA in the hippocampus of patients with temporal lobe epilepsy

1 reference

12 December 2020

Actions of dehydroepiandrosterone and its sulfate in the central nervous system: effects on cognition and emotion in animals and humans

1 reference

12 December 2020

Peripheral steroid sulfatase inhibition potentiates improvement of memory retention for hippocampally administered dehydroepiandrosterone sulfate but not pregnenolone sulfate.

1 reference

12 December 2020

Sex- and age-specific differences in human brain CYP11A1 mRNA expression

1 reference

12 December 2020

Relationships among cortisol (CRT), dehydroepiandrosterone-sulfate (DHEAS), and memory in a longitudinal study of healthy elderly men and women

1 reference

12 December 2020

Neurosteroids: biosynthesis and function of these novel neuromodulators

1 reference

12 December 2020

Dehydroepiandrosterone sulfate and psychiatric measures in a frail, elderly residential care population

1 reference

12 December 2020

DHEA-S plasma levels and incidence of Alzheimer's disease.

1 reference

12 December 2020

Prolonged intracerebroventricular infusion of neurosteroids affects cognitive performances in the mouse.

1 reference

12 December 2020

Acute oral administration of dehydroepiandrosterone in male subjects: effect of age on bioavailability, sulfoconjugation and bioconversion in other steroids

1 reference

12 December 2020

Serum profile of dehydroepiandrosterone (DHEA) concentrations in DHEA-supplemented elderly subjects

1 reference

12 December 2020

Dehydroepiandrosterone (DHEA), DHEA sulfate, and aging: contribution of the DHEAge Study to a sociobiomedical issue

1 reference

12 December 2020

Sex differences in the pharmacokinetics of dehydroepiandrosterone (DHEA) after single- and multiple-dose administration in healthy older adults

1 reference

12 December 2020

The relationship between longitudinal declines in dehydroepiandrosterone sulfate concentrations and cognitive performance in older men.

1 reference

12 December 2020

Dehydroepiandrosterone replacement administration: pharmacokinetic and pharmacodynamic studies in healthy elderly subjects

1 reference

12 December 2020

Pathways of dehydroepiandrosterone formation in rat brain glia.

1 reference

12 December 2020

Salivary cortisol and DHEA: association with measures of cognition and well-being in normal older men, and effects of three months of DHEA supplementation

1 reference

12 December 2020

Steroid synthesis and metabolism in the nervous system: trophic and protective effects

1 reference

12 December 2020

Neurosteroid synthesis by cytochrome p450-containing systems localized in the rat brain hippocampal neurons: N-methyl-D-aspartate and calcium-dependent synthesis

1 reference

12 December 2020

Dehydroepiandrosterone supplementation in healthy men with an age-related decline of dehydroepiandrosterone secretion

1 reference

12 December 2020

Neurosteroid metabolism in the human brain

1 reference

12 December 2020

Neurosteroids: recent findings

1 reference

12 December 2020

Dehydroepiandrosterone and the relationship with aging and memory: a possible link with protein kinase C functional machinery

1 reference

12 December 2020

Progesterone synthesis and myelin formation in peripheral nerves

1 reference

12 December 2020

Neurosteroids: biochemistry and clinical significance

1 reference

12 December 2020

In vivo dehydroepiandrosterone restores age-associated defects in the protein kinase C signal transduction pathway and related functional responses

1 reference

12 December 2020

1 reference

12 December 2020

Neurosteroids: endogenous bimodal modulators of the GABAA receptor. Mechanism of action and physiological significance

1 reference

12 December 2020

Long-term longitudinal measurements of plasma dehydroepiandrosterone sulfate in normal men

1 reference

12 December 2020

Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C

1 reference

12 December 2020

P300 and traffic scenes: the effect of temazepam

1 reference

12 December 2020

Plasma dehydroepiandrosterone sulfate in Alzheimer's disease

1 reference

12 December 2020

Memory-enhancing effects in male mice of pregnenolone and steroids metabolically derived from it.

1 reference

12 December 2020

Pattern of Plasma Dehydroepiandrosterone Sulfate Levels in Humans from Birth to Adulthood: Evidence for Testicular Production*

1 reference

12 December 2020

EEG and auditory evoked potential P300 compared with psychometric tests in assessing vigilance after benzodiazepine sedation and antagonism.

1 reference

12 December 2020

Immunoreactive cytochrome P-45017 in rat and guineapig gonads, adrenal glands and brain

1 reference

12 December 2020

Serum dehydroepiandrosterone sulfate in Alzheimer's disease and in multi-infarct dementia.

1 reference

12 December 2020

Steroid binding at sigma receptors: CNS and immunological implications.

1 reference

12 December 2020

Sigma receptors: biology and function

1 reference

12 December 2020

Marked attenuation of ultradian and circadian rhythms of dehydroepiandrosterone in postmenopausal women: evidence for a reduced 17,20-desmolase enzymatic activity

1 reference

12 December 2020

Effects of post-training bicuculline and muscimol on retention: lack of state dependency

1 reference

12 December 2020

Regulation of phorbol ester binding and protein kinase C activity in aged rat brain.

1 reference

12 December 2020

Neurosteroids: a new brain function?

1 reference

12 December 2020

Steroid hormone metabolites are barbiturate-like modulators of the GABA receptor

1 reference

12 December 2020

Effect of age on brain cortical protein kinase C and its mediation of 5-hydroxytryptamine release

1 reference

12 December 2020

Reduced plasma dehydroepiandrosterone concentrations in Alzheimer's disease.

1 reference

12 December 2020

Neurosteroids: biosynthesis of pregnenolone and progesterone in primary cultures of rat glial cells

1 reference

12 December 2020

Effects of dehydroepiandrosterone and its sulfate on brain tissue in culture and on memory in mice.

1 reference

12 December 2020

Dehydroepiandrosterone and its sulfate enhance memory retention in mice

1 reference

12 December 2020

Dehydroepiandrosterone sulfate improves memory in aging mice.

1 reference

12 December 2020

Control of secretion and the function of C19-delta 5-steroids of the human adrenal gland

1 reference

12 December 2020

Neurosteroids: cytochrome P-450scc in rat brain

1 reference

12 December 2020

A steroid anesthetic prolongs inhibitory postsynaptic currents in cultured rat hippocampal neurons

1 reference

12 December 2020

The secretion of dehydroepiandrosterone and dehydroepiandrosterone sulphate in man

1 reference

12 December 2020

Modulation of the GABA receptor complex by a steroid anaesthetic

1 reference

12 December 2020

Are the Amplitudes of Visual Evoked Potentials Sensitive Indices of Hangover Effects After Repeated Doses of Benzodiazepines?

1 reference

12 December 2020

Pregnenolone and its sulfate ester in the rat brain

1 reference

12 December 2020

Characterization and measurement of dehydroepiandrosterone sulfate in rat brain

1 reference

12 December 2020

Serum levels of testosterone precursors, testosterone and estradiol in 10 animal species

1 reference

12 December 2020

Phorbol esters increase the amount of Ca2+, phospholipid-dependent protein kinase associated with plasma membrane

1 reference

12 December 2020

Neurosteroids and GABAA receptor function.

1 reference

12 December 2020

3 alpha-Hydroxy-5 beta-pregnan-20-one sulfate: a negative modulator of the NMDA-induced current in cultured neurons.

1 reference

12 December 2020

Neurosteroids Affect Spatial/Reference, Working, and Long-Term Memory of Female Rats

1 reference

12 December 2020

Steroidogenic enzyme P450c17 is expressed in the embryonic central nervous system

1 reference

12 December 2020

Avian neurosteroids. I. Pregnenolone biosynthesis in the quail brain

1 reference

12 December 2020

Avian neurosteroids. II. Localization of a cytochrome P450scc-like substance in the quail brain

1 reference

12 December 2020

Localization of protein kinases by anchoring proteins: a theme in signal transduction

1 reference

12 December 2020

Neurosteroids, via sigma receptors, modulate the [3H]norepinephrine release evoked by N-methyl-D-aspartate in the rat hippocampus

1 reference

12 December 2020

Expression of the steroidogenic enzyme P450scc in the central and peripheral nervous systems during rodent embryogenesis

1 reference

12 December 2020

Protein kinase C activity, translocation, and conventional isoforms in aging rat brain

1 reference

12 December 2020

The neurosteroid pregnenolone sulfate blocks NMDA antagonist-induced deficits in a passive avoidance memory task.

1 reference

12 December 2020

Pharmacological evidence for a role of long-term potentiation in memory.

1 reference

12 December 2020

Immunocytochemical localization and biological activity of 3 beta-hydroxysteroid dehydrogenase in the central nervous system of the frog

1 reference

12 December 2020

Ameliorating effects of sigma receptor ligands on the impairment of passive avoidance tasks in mice: involvement in the central acetylcholinergic system.

1 reference

12 December 2020

Dehydroepiandrosterone sulphate (DHEAS) in the oldest old, aged 85 and over.

1 reference

12 December 2020

Aging and hypothalamic-pituitary-adrenal response to challenge in humans

1 reference

12 December 2020

Delineating biochemical and functional properties of sigma receptors: emerging concepts

1 reference

12 December 2020

Neurosteroid biosynthesis: genes for adrenal steroidogenic enzymes are expressed in the brain

1 reference

12 December 2020

A prospective study of dehydroepiandrosterone sulfate and cognitive function in an older population: the Rancho Bernardo Study.

1 reference

12 December 2020

Effects of peroxidation and aging on rat neocortical ACh-release and protein kinase C.

1 reference

12 December 2020

Protein kinase C--a question of specificity

1 reference

12 December 2020

Interaction of GABAergic and beta-noradrenergic drugs in the regulation of memory storage

1 reference

12 December 2020

The protein kinase C family for neuronal signaling

1 reference

12 December 2020

Cloning of an intracellular receptor for protein kinase C: a homolog of the beta subunit of G proteins

1 reference

12 December 2020

Current hypotheses on sigma receptors and their physiological role: possible implications in psychiatry

1 reference

12 December 2020

Infusion of neurosteroids into the nucleus basalis magnocellularis affects cognitive processes in the rat.

1 reference

12 December 2020

Steroids and their conjugates in the mammalian brain

1 reference

12 December 2020

A synaptic model of memory: long-term potentiation in the hippocampus

1 reference

12 December 2020

Pregnenolone sulfate antagonizes dizocilpine amnesia: role for allopregnanolone.

1 reference

12 December 2020

Involvement of sigma 1 receptor in (+)-N-allylnormetazocine-stimulated hippocampal cholinergic functions in rats

1 reference

12 December 2020

Potentiation of neuronal NMDA response induced by dehydroepiandrosterone and its suppression by progesterone: effects mediated via sigma receptors.

1 reference

12 December 2020

Interaction of protein kinase C with RACK1, a receptor for activated C-kinase: a role in beta protein kinase C mediated signal transduction

1 reference

12 December 2020

Dehydroepiandrosterone sulfate in a long-term care aged population

1 reference

12 December 2020

Dehydroepiandrosterone sulfate and aging

1 reference

12 December 2020

Biosynthesis of DHEAS by the human adrenal cortex and its age-related decline

1 reference

12 December 2020

Antidepressant and cognition-enhancing effects of DHEA in major depression.

1 reference

12 December 2020

Modulation of NMDA and dopaminergic neurotransmissions by sigma ligands: possible implications for the treatment of psychiatric disorders

1 reference

12 December 2020

Cloning of the rat steroid sulfatase gene (Sts), a non-pseudoautosomal X-linked gene that undergoes X inactivation

1 reference

12 December 2020

Cloning and expression of the mouse pseudoautosomal steroid sulphatase gene (Sts).

1 reference

12 December 2020

Long-term potentiation and N-methyl-D-aspartate receptors: foundations of memory and neurologic disease?

1 reference

12 December 2020

Serum dehydroepiandrosterone (DHEA) and DHEA-sulfate (DHEA-S) in Alzheimer's disease and in cerebrovascular dementia.

1 reference

12 December 2020

Messenger RNAs encoding steroidogenic enzymes are expressed in rodent brain

1 reference

12 December 2020

Dehydroepiandrosterone (DHEA): a fountain of youth?

1 reference

12 December 2020

Longitudinal study of basal cortisol levels in healthy elderly subjects: evidence for subgroups.

1 reference

12 December 2020

Neurosteroids block the memory-impairing effects of ethanol in mice

1 reference

12 December 2020

The zona reticularis is the site of biosynthesis of dehydroepiandrosterone and dehydroepiandrosterone sulfate in the adult human adrenal cortex resulting from its low expression of 3 beta-hydroxysteroid dehydrogenase.

1 reference

12 December 2020

The neurosteroid pregnenolone sulfate reduces learning deficits induced by scopolamine and has promnestic effects in mice performing an appetitive learning task.

1 reference

12 December 2020

Beneficial effects of sigma agonists on the age-related learning impairment in the senescence-accelerated mouse (SAM).

1 reference

12 December 2020

Cortisol, dehydroepiandrosterone (DHEA), and DHEA sulfate in the cerebrospinal fluid of man: relation to blood levels and the effects of age.

1 reference

12 December 2020

Functional impairment in protein kinase C by RACK1 (receptor for activated C kinase 1) deficiency in aged rat brain cortex.

1 reference

12 December 2020

DHEA: a hormone with multiple effects.

1 reference

12 December 2020

Potentiation by dehydroepiandrosterone of the neuronal response to N-methyl-D-aspartate in the CA3 region of the rat dorsal hippocampus: an effect mediated via sigma receptors.

1 reference

12 December 2020

Dehydroepiandrosterone and dehydroepiandrosterone sulfate as neuroactive neurosteroids.

1 reference

12 December 2020

Ameliorating effect of SA4503, a novel sigma 1 receptor agonist, on memory impairments induced by cholinergic dysfunction in rats.

1 reference

12 December 2020

Steroid sulfotransferases

1 reference

12 December 2020

Modulation by neurosteroids of the in vivo (+)-[3H]SKF-10,047 binding to sigma 1 receptors in the mouse forebrain.

1 reference

12 December 2020

Memory enhancement mediated by the steroid sulfatase inhibitor (p-O-sulfamoyl)-N-tetradecanoyl tyramine

1 reference

12 December 2020

Dehydroepiandrosterone (DHEA) treatment of depression

1 reference

12 December 2020

Neuroprotective and anti-amnesic potentials of sigma (sigma) receptor ligands

1 reference

12 December 2020

Neurosteroid prolongs GABAA channel deactivation by altering kinetics of desensitized states

1 reference

12 December 2020

Hydroxysteroid sulfotransferase activity in the rat brain and liver as a function of age and sex.

1 reference

12 December 2020

Effects of a two-week physiological dehydroepiandrosterone substitution on cognitive performance and well-being in healthy elderly women and men.

1 reference

12 December 2020

A single administration of dehydroepiandrosterone does not enhance memory performance in young healthy adults, but immediately reduces cortisol levels.

1 reference

12 December 2020

Expression of steroid sulfatase during embryogenesis.

1 reference

12 December 2020

Aging alters zonation in the adrenal cortex of men

1 reference

12 December 2020

Neurosteroids: deficient cognitive performance in aged rats depends on low pregnenolone sulfate levels in the hippocampus

1 reference

12 December 2020

Distribution and characterization of neurosteroid sulfatase from the bovine brain.

1 reference

12 December 2020

Cytochrome P450 side-chain cleavage enzyme in the cerebellar Purkinje neuron and its neonatal change in rats.

1 reference

12 December 2020

Sigma1 (sigma 1) receptor agonists and neurosteroids attenuate B25-35-amyloid peptide-induced amnesia in mice through a common mechanism.

1 reference

12 December 2020

Dehydroepiandrosterone (DHEA) and DHEA-sulfate (DHEAS) protect hippocampal neurons against excitatory amino acid-induced neurotoxicity

1 reference

12 December 2020

Modulation of GABA-gated chloride ion influx in the brain by dehydroepiandrosterone and its metabolites.

1 reference

12 December 2020

Detection of P450c17-independent pathways for dehydroepiandrosterone (DHEA) biosynthesis in brain glial tumor cells

1 reference

12 December 2020

Dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEAS) as neuroactive neurosteroids

1 reference

12 December 2020

Dehydroepiandrosterone: a potential signalling molecule for neocortical organization during development

1 reference

12 December 2020

1 reference

12 December 2020

Neuropsychiatric function and dehydroepiandrosterone sulfate in elderly women: a prospective study

1 reference

12 December 2020

The effects of neurosteroids on acquisition and retention of a modified passive-avoidance learning task in mice.

1 reference

12 December 2020

Cognitive and noncognitive symptoms in dementia patients: relationship to cortisol and dehydroepiandrosterone.

1 reference

12 December 2020

The modulation by neurosteroids of the scopolamine-induced learning impairment in mice involves an interaction with sigma1 (sigma1) receptors

1 reference

12 December 2020

Age- and region-specific expressions of the messenger RNAs encoding for steroidogenic enzymes p450scc, P450c17 and 3beta-HSD in the postnatal rat brain

1 reference

12 December 2020

Effects of dehydroepiandrosterone replacement in elderly men on event-related potentials, memory, and well-being

1 reference

12 December 2020

Dehydroepiandrosterone sulfate (DHEA-S) and psychiatric and laboratory measures of frailty in a residential care population.

1 reference

12 December 2020

Steroid hormones, memory and mood in a healthy elderly population

1 reference

12 December 2020

Opposing effects of DHEA replacement in elderly subjects on declarative memory and attention after exposure to a laboratory stressor.

1 reference

12 December 2020

Steroidogenic acute regulatory protein (StAR) transcripts constitutively expressed in the adult rat central nervous system: colocalization of StAR, cytochrome P-450SCC (CYP XIA1), and 3beta-hydroxysteroid dehydrogenase in the rat brain

1 reference

12 December 2020

Neurosteroids: a novel function of the brain

1 reference

12 December 2020

Dehydroepiandrosterone: biosynthesis and metabolism in the brain

1 reference

12 December 2020

Immunocytochemical localization and biological activity of hydroxysteroid sulfotransferase in the frog brain

1 reference

12 December 2020

10.1111/J.1527-3458.2003.TB00242.X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12595910%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12595910%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

PubMed publication ID

12595910

1 reference