(Q35069583)

PubMed publication ID

6 August 2017

1 reference

title

JL 13, an atypical antipsychotic: a preclinical review (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741663&resulttype=core&format=json

12 May 2020

author name string

Bart A Ellenbroek

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741663&resulttype=core&format=json

12 May 2020

Jean-François Liégeois

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741663&resulttype=core&format=json

12 May 2020

publication date

1 January 2003

1 reference

PubMed publication ID

12595911

CNS Neuroscience & Therapeutics

6 August 2017

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741663&resulttype=core&format=json

12 May 2020

volume

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741663&resulttype=core&format=json

12 May 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741663&resulttype=core&format=json

12 May 2020

page(s)

41-56

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741663&resulttype=core&format=json

Placebo-controlled study of the D4/5-HT2A antagonist fananserin in the treatment of schizophrenia

12 May 2020

cites work

1 reference

12 December 2020

Dopamine D4 receptor antagonist reversal of subchronic phencyclidine-induced object retrieval/detour deficits in monkeys.

1 reference

12 December 2020

Serotonin (5-HT)2A receptor activation enhances dialysate levels of dopamine and noradrenaline, but not 5-HT, in the frontal cortex of freely-moving rats

1 reference

12 December 2020

Novel antipsychotics: comparison of weight gain liabilities.

1 reference

12 December 2020

New and old antipsychotics versus clozapine in a monkey model: adverse effects and antiamphetamine effects

1 reference

12 December 2020

Oxidation sensitivity may be a useful tool for the detection of the hematotoxic potential of newly developed molecules: application to antipsychotic drugs

1 reference

12 December 2020

Enhanced cortical dopamine output and antipsychotic-like effects of raclopride by alpha2 adrenoceptor blockade

1 reference

12 December 2020

JL13, a pyridobenzoxazepine compound with potential atypical antipsychotic activity, increases extracellular dopamine in the prefrontal cortex, but not in the striatum and the nucleus accumbens of rats

1 reference

12 December 2020

Hypochlorous acid, a major oxidant produced by activated neutrophils, has low effect on two pyridobenzazepine derivatives, JL 3 and JL 13

1 reference

12 December 2020

5-HT(1A) receptor activation contributes to ziprasidone-induced dopamine release in the rat prefrontal cortex

1 reference

12 December 2020

Binding of antipsychotic drugs to human brain receptors focus on newer generation compounds

1 reference

12 December 2020

Comparative study of typical neuroleptics, clozapine and newly synthesized clozapine-analogues: correlations between neurochemistry and behaviour

1 reference

12 December 2020

Effects of olanzapine and other antipsychotic agents on responding maintained by a conflict schedule

1 reference

12 December 2020

New dibenzazepine derivatives with disinhibitory and/or antidepressant potential: neurochemical and behavioural study in the open-field and forced swimming tests.

1 reference

12 December 2020

5-HT(2A) and D(2) receptor blockade increases cortical DA release via 5-HT(1A) receptor activation: a possible mechanism of atypical antipsychotic-induced cortical dopamine release

1 reference

12 December 2020

Interactions between monoamines, glutamate, and GABA in schizophrenia: new evidence

1 reference

12 December 2020

Distribution of the methylpiperazinopyridobenzoxazepine derivative JL13, a potential antipsychotic, in rat brain

1 reference

12 December 2020

Effects of JL13, a pyridobenzoxazepine with potential atypical antipsychotic activity, in animal models for schizophrenia

1 reference

12 December 2020

Genetic dissection of atypical antipsychotic-induced weight gain: novel preliminary data on the pharmacogenetic puzzle

1 reference

12 December 2020

Elevation of prolactin levels by atypical antipsychotics

1 reference

12 December 2020

Minimal effects of JL 13, a pyridobenzoxazepine derivative with an antipsychotic potential, on circulating prolactin levels in male rats

1 reference

12 December 2020

5-HT(2A) receptor antagonism potentiates haloperidol-induced dopamine release in rat medial prefrontal cortex and inhibits that in the nucleus accumbens in a dose-dependent manner

1 reference

12 December 2020

Behavioral evidence for differential adaptation of the serotonergic system after acute and chronic treatment with (+/- )-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) or ketanserin

1 reference

12 December 2020

Possible role of free radical formation in clozapine (clozaril)-induced agranulocytosis

1 reference

12 December 2020

Stimulant effect of the beta-carboline FG 7142 in the open-field test.

1 reference

12 December 2020

Are 5-HT2 antagonists endowed with anxiolytic properties in rodents?

1 reference

12 December 2020

Dopamine in schizophrenia: a review and reconceptualization

1 reference

12 December 2020

A review of evidence for GABergic predominance/glutamatergic deficit as a common etiological factor in both schizophrenia and affective psychoses: More support for a continuum hypothesis of ?functional? psychosis

1 reference

12 December 2020

Effects of spiperone, raclopride, SCH 23390 and clozapine on apomorphine inhibition of sensorimotor gating of the startle response in the rat

1 reference

12 December 2020

D1 Dopamine Receptors in Prefrontal Cortex: Involvement in Working Memory

1 reference

12 December 2020

Cloning of the gene for a human dopamine D4 receptor with high affinity for the antipsychotic clozapine

1 reference

12 December 2020

Histaminergic transmission in the mammalian brain

1 reference

12 December 2020

D1/D2 dopamine receptor interaction at the biochemical level

1 reference

12 December 2020

Acute effects of typical and atypical antipsychotic drugs on the release of dopamine from prefrontal cortex, nucleus accumbens, and striatum of the rat: an in vivo microdialysis study

1 reference

12 December 2020

Comparative study of the behavioral, neurophysiological, and motor effects of psychotropic drugs in the dog.

1 reference

12 December 2020

Molecular cloning and characterization of a novel dopamine receptor (D3) as a target for neuroleptics

1 reference

12 December 2020

Anxiolytic potential of sulpiride, clozapine and derivatives in the open-field test

1 reference

12 December 2020

Classification of typical and atypical antipsychotic drugs on the basis of dopamine D-1, D-2 and serotonin2 pKi values

1 reference

12 December 2020

Classification of neuroleptic drugs according to their ability to inhibit apomorphine-induced locomotion and gnawing: Evidence for two different mechanisms of action

1 reference

12 December 2020

The history of clozapine

1 reference

12 December 2020

The paw test: a behavioural paradigm for differentiating between classical and atypical neuroleptic drugs

1 reference

12 December 2020

The Paw test: an animal model for neuroleptic drugs which fulfils the criteria for pharmacological isomorphism

1 reference

12 December 2020

GABAA receptor blockers reverse the inhibitory effect of GABA on brain-specific [35S]TBPS binding

1 reference

12 December 2020

Clozapine for the treatment-resistant schizophrenic. A double-blind comparison with chlorpromazine

1 reference

12 December 2020

Differential effects of haloperidol, clozapine, and fluperlapine on tuberoinfundibular dopamine neurons and prolactin secretion in the rat

1 reference

12 December 2020

Effect profile of a chemically new broad spectrum neuroleptic of the dibenzo-diazepine group

1 reference

12 December 2020

Behavioral despair in mice: a primary screening test for antidepressants

1 reference

12 December 2020

Remoxipride, a new potential antipsychotic compound with selective antidopaminergic actions in the rat brain

1 reference

12 December 2020

The olfactory tubercle as a site of action of neuroleptics with an atypical profile in the paw test: effect of risperidone, prothipendyl, ORG 5222, sertindole and olanzapine

1 reference

12 December 2020

Absence of detectable striatal dopamine D4 receptors in drug-treated schizophrenia

1 reference

12 December 2020

Role of striatal dopamine D2 receptors in the paw test, an animal model for the therapeutic efficacy and extrapyramidal side effects of neuroleptic drugs

1 reference

12 December 2020

Eating disorder and epilepsy in mice lacking 5-HT2c serotonin receptors

1 reference

12 December 2020

Peroxidase-catalysed oxidation of different dibenzazepine derivatives

1 reference

12 December 2020

Modulation of the clozapine structure increases its selectivity for the dopamine D4 receptor

1 reference

12 December 2020

Full-length cDNA cloning and distribution of human dopamine D4 receptor

1 reference

12 December 2020

Combined antagonism of adrenoceptors and dopamine and 5-HT receptors underlies the atypical profile of clozapine

1 reference

12 December 2020

Seroquel (ICI 204,636) restores prepulse inhibition of acoustic startle in apomorphine-treated rats: Similarities to clozapine

1 reference

12 December 2020

Distribution of putative D4 dopamine receptors in postmortem striatum from patients with schizophrenia.

1 reference

12 December 2020

Aplastic anaemia and remoxipride

1 reference

12 December 2020

Shock-induced ultrasonic vocalization in young adult rats: a model for testing putative anti-anxiety drugs

1 reference

12 December 2020

Pyridobenzoxazepine and pyridobenzothiazepine derivatives as potential central nervous system agents: synthesis and neurochemical study.

1 reference

12 December 2020

The Role of Serotonin Receptor Subtypes in the Behavioural Effects of Neuroleptic Drugs. A Paw Test Study in Rats

1 reference

12 December 2020

Peripheral and central adrenoceptor modulation of the behavioural effects of clozapine in the paw test

1 reference

12 December 2020

Are Striatal Dopamine D4 Receptors Increased in Schizophrenia?

1 reference

12 December 2020

Differential effects of locally administered clozapine and haloperidol on dopamine efflux in the rat prefrontal cortex and caudate-putamen

1 reference

12 December 2020

The head-twitch response in the least shrew (Cryptotis parva) is a 5-HT2- and not a 5-HT1C-mediated phenomenon

1 reference

12 December 2020

Effects of four antipsychotics on punished responding in rats

1 reference

12 December 2020

New pyridobenzodiazepine derivatives as potential antipsychotics: synthesis and neurochemical study

1 reference

12 December 2020

Tissue concentrations of clozapine and its metabolites in the rat

1 reference

12 December 2020

Assessing the validity of an animal model of deficient sensorimotor gating in schizophrenic patients

1 reference

12 December 2020

Dopamine D4 receptors elevated in schizophrenia

1 reference

12 December 2020

Differentiation of haloperidol and clozapine using a complex operant schedule in the dog.

1 reference

12 December 2020

Clozapine-induced agranulocytosis: a situation report up to August 1976.

1 reference

12 December 2020

Effects of dopamine antagonists on neuronal histamine release in the striatum of rats subjected to acute and chronic treatments with methamphetamine.

1 reference

12 December 2020

Activity of “Seroquel” (ICI 204,636) in Animal Models for Atypical Properties of Antipsychotics: A Comparison with Clozapine

1 reference

12 December 2020

Risperidone compared with new and reference antipsychotic drugs: in vitro and in vivo receptor binding

1 reference

12 December 2020

Behavioral effects of sertindole, risperidone, clozapine and haloperidol in Cebus monkeys

1 reference

12 December 2020

The effects of a selective D4 dopamine receptor antagonist (L-745,870) in acutely psychotic inpatients with schizophrenia. D4 Dopamine Antagonist Group

1 reference

12 December 2020

Structural features associated with reactive metabolite formation in clozapine analogues

1 reference

12 December 2020

Discriminative-stimulus effects of clozapine in squirrel monkeys: comparison with conventional and novel antipsychotic drugs.

1 reference

12 December 2020

JL 13, a potential successor to clozapine, is less sensitive to oxidative phenomena

1 reference

12 December 2020

JL13, a pyridobenzoxazepine compound with potential atypical antipsychotic activity: a review of its behavioural properties

1 reference

12 December 2020

Comparative characterisation of the discriminative stimulus properties of clozapine and other antipsychotics in rats.

1 reference

12 December 2020

The agonist activities of the putative antipsychotic agents, L-745,870 and U-101958 in HEK293 cells expressing the human dopamine D4.4 receptor

1 reference

12 December 2020

Clozapine and several other antipsychotic/antidepressant drugs preferentially block the same 'core' fraction of GABA(A) receptors.

1 reference

12 December 2020

Atypical neuroleptics enhance histamine turnover in brain via 5-Hydroxytryptamine2A receptor blockade.

1 reference

12 December 2020

Effects of antipsychotic drugs on extracellular dopamine levels in rat medial prefrontal cortex and nucleus accumbens.

1 reference

12 December 2020

10.1111/J.1527-3458.2003.TB00243.X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741663&resulttype=core&format=json

12 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741663&resulttype=core&format=json

12 May 2020

PubMed publication ID

12595911

1 reference