(Q35076513)

6 August 2017

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title

Design of the lac gene circuit revisited (English)

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6 August 2017

Michael A Savageau

1

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6 August 2017

21 March 2011

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6 August 2017

20

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inferred from page(s)

published in

Mathematical Biosciences

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6 August 2017

231

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6 August 2017

1

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6 August 2017

19-38

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PubMed ID

21414326

maintained by WikiProject

6 August 2017

WikiProject Mathematics

0 references

cites work

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Phenotypic repertoire of the FNR regulatory network in Escherichia coli

8 July 2018

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Relating mutant genotype to phenotype via quantitative behavior of the NADPH redox cycle in human erythrocytes

8 July 2018

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Automated construction and analysis of the design space for biochemical systems

8 July 2018

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Quantifying E. coli Proteome and Transcriptome with Single-Molecule Sensitivity in Single Cells

8 July 2018

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Duplication frequency in a population of Salmonella enterica rapidly approaches steady state with or without recombination

8 July 2018

1 reference

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Qualitatively distinct phenotypes in the design space of biochemical systems

8 July 2018

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Quantifying global tolerance of biochemical systems: design implications for moiety-transfer cycles

8 July 2018

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Phenotypes and tolerances in the design space of biochemical systems

8 July 2018

1 reference

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The mechanisms of carbon catabolite repression in bacteria

8 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126112

How phosphotransferase system-related protein phosphorylation regulates carbohydrate metabolism in bacteria

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126112

In silico evolved lac operons exhibit bistability for artificial inducers, but not for lactose

8 July 2018

1 reference

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ENZYME INDUCTION AS AN ALL-OR-NONE PHENOMENON

8 July 2018

1 reference

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Rules for biological regulation based on error minimization

8 July 2018

1 reference

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Induction of the lac promoter in the absence of DNA loops and the stoichiometry of induction

8 July 2018

1 reference

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Inferring the in vivo looping properties of DNA.

8 July 2018

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Design of gene circuits: lessons from bacteria

8 July 2018

1 reference

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Genetic regulatory mechanisms in the synthesis of proteins

8 July 2018

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8 July 2018

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Design principles for elementary gene circuits: Elements, methods, and examples

27 September 2018

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Regulation of gene expression in the PTS in Escherichia coli: the role and interactions of Mlc.

8 July 2018

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The identification of a new family of sugar efflux pumps in Escherichia coli.

8 July 2018

1 reference

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Design of gene circuitry by natural selection: analysis of the lactose catabolic system in Escherichia coli.

8 July 2018

1 reference

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Rules for coupled expression of regulator and effector genes in inducible circuits.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126112

Mathematics of cellular control processes II. Positive feedback to one gene

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126112

Genetic regulatory mechanisms and the ecological niche of Escherichia coli

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126112

lac Repressor-operator interaction. VI. The natural inducer of the lac operon.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126112

The three operators of the lac operon cooperate in repression

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126112

Quantitative Aspects of Protein Induction

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126112

Sustained oscillations and threshold phenomena in an operon control circuit

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126112

A quantitation of the factors which affect the hydrolase and transgalactosylase activities of β-galactosidase (E. coli) on lactose

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126112

Determinants of bistability in induction of the Escherichia coli lac operon.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126112

Bistability of the lac operon during growth of Escherichia coli on lactose and lactose+glucose

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126112

Bistable behavior in a model of the lac operon in Escherichia coli with variable growth rate

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126112

In vitro reconstitution of catabolite repression in Escherichia coli.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126112

Multistability in the lactose utilization network of Escherichia coli

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126112

Alternative designs for a genetic switch: analysis of switching times using the piecewise power-law representation

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126112

Functional and biochemical characterization of Escherichia coli sugar efflux transporters.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126112

Mathematical model of the lac operon: inducer exclusion, catabolite repression, and diauxic growth on glucose and lactose.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126112

Subunit structure of regulator proteins influences the design of gene circuitry: analysis of perfectly coupled and completely uncoupled circuits.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126112

THE PROPERTIES OF REPRESSOR AND THE KINETICS OF ITS ACTION

27 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21414326

12 December 2020

inferred from PubMed ID database lookup

Chemical instabilities of "all-or-none" type in beta - galactosidase induction and active transport

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21414326

12 December 2020

inferred from PubMed ID database lookup

Escherichia coli growth on lactose requires cycling of beta-galactosidase products into the medium

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21414326

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1016/J.MBS.2011.03.008

1 reference

6 August 2017

1 reference

6 August 2017

1 reference

PubMed ID

21414326