(Q35078362)

6 August 2017

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title

Genetic alterations in the ageing immune system: impact on infection and cancer (English)

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6 August 2017

Rita B Effros

1

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6 August 2017

publication date

1 January 2003

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Mechanisms of Ageing and Development

6 August 2017

published in

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6 August 2017

volume

124

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6 August 2017

issue

1

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6 August 2017

page(s)

71-77

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Long-term culture of monoclonal human T lymphocytes: models for immunosenescence?

6 August 2017

cites work

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7 January 2021

Extension of life-span by introduction of telomerase into normal human cells

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7 January 2021

CD28 expression in T cell aging and human longevity

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7 January 2021

From cells to organisms: can we learn about aging from cells in culture?

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7 January 2021

Genes of the major histocompatibility complex and the evolutionary genetics of lifespan

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7 January 2021

Replicative senescence in the immune system: impact of the Hayflick limit on T-cell function in the elderly

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7 January 2021

Costimulatory mechanisms in the elderly

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7 January 2021

Telomeres and HIV disease

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7 January 2021

Decline in CD28+ T cells in centenarians and in long-term T cell cultures: a possible cause for both in vivo and in vitro immunosenescence

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7 January 2021

Replicative senescence of T cells: does the Hayflick Limit lead to immune exhaustion?

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7 January 2021

Stress response of senescent T lymphocytes: reduced hsp70 is independent of the proliferative block

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7 January 2021

Immune Parameters in a Longitudinal Study of a Very Old Population of Swedish People: A Comparison Between Survivors and Nonsurvivors

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7 January 2021

The immunology of exceptional individuals: the lesson of centenarians.

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7 January 2021

Population biology of lymphocytes: the flight for survival

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7 January 2021

Value of immunological markers in predicting responsiveness to influenza vaccination in elderly individuals

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7 January 2021

Long-term in vitro growth of human T cell clones: can postmitotic 'senescent' cell populations be defined?

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7 January 2021

Immortalization of human CD8+ T cell clones by ectopic expression of telomerase reverse transcriptase

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7 January 2021

Identification of the T cell clones expanding within both CD8(+)CD28(+) and CD8(+)CD28(-) T cell subsets in recipients of allogeneic hematopoietic cell grafts and its implication in post-transplant skewing of T cell receptor repertoire

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7 January 2021

Senescent fibroblasts promote epithelial cell growth and tumorigenesis: a link between cancer and aging

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7 January 2021

CD28/B7 system of T cell costimulation

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7 January 2021

Association between the MHC class I gene HFE polymorphisms and longevity: a study in Sicilian population

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7 January 2021

Role of cytomegalovirus in the T cell changes seen in elderly individuals

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7 January 2021

Age, thymopoiesis, and CD4+ T-lymphocyte regeneration after intensive chemotherapy

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7 January 2021

eNOS activity is reduced in senescent human endothelial cells: Preservation by hTERT immortalization

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7 January 2021

T cells: A proliferation of costimulatory molecules.

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7 January 2021

Human T lymphocytes possess a limited in vitro life span

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7 January 2021

The flow cytometric analysis of telomere length in antigen-specific CD8+ T cells during acute Epstein-Barr virus infection

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7 January 2021

Differentiation of human CD8 T cells: implications for in vivo persistence of CD8+ CD28- cytotoxic effector clones.

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7 January 2021

Clonal populations of T cells in normal elderly humans: the T cell equivalent to "benign monoclonal gammapathy".

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7 January 2021

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7 January 2021

Peripheral T lymphocytes: expansion potential and homeostatic regulation of pool sizes and CD4/CD8 ratios in vivo

1 reference

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7 January 2021

Upstream-downstream: CD28 cosignaling pathways and T cell function

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7 January 2021

Human memory T cells: lessons from stem cell transplantation

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7 January 2021

CD28, CTLA-4 and their ligands: who does what and to whom?

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2802%2900171-9

7 January 2021

Crosslinking of the T cell-specific accessory molecules CD7 and CD28 modulates T cell adhesion

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2802%2900171-9

7 January 2021

A stochastic model of cell replicative senescence based on telomere shortening, oxidative stress, and somatic mutations in nuclear and mitochondrial DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2802%2900171-9

7 January 2021

Divergent telomerase and CD28 expression patterns in human CD4 and CD8 T cells following repeated encounters with the same antigenic stimulus

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2802%2900171-9

7 January 2021

Peripheral expansion of pre-existing mature T cells is an important means of CD4+ T-cell regeneration HIV-infected adults

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2802%2900171-9

7 January 2021

Tales of tails: regulation of telomere length and telomerase activity during lymphocyte development, differentiation, activation, and aging

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2802%2900171-9

7 January 2021

10.1016/S0047-6374(02)00171-9

Identifiers

DOI

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6 August 2017

1 reference