(Q35079295)

6 August 2017

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title

Molecular handling of cadmium in transporting epithelia (English)

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6 August 2017

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Rudolfs K Zalups

1

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6 August 2017

Sarfaraz Ahmad

series ordinal

2

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6 August 2017

publication date

1 February 2003

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Toxicology and Applied Pharmacology

6 August 2017

published in

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6 August 2017

volume

186

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6 August 2017

issue

3

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6 August 2017

page(s)

163-188

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A novel mammalian iron-regulated protein involved in intracellular iron metabolism

6 August 2017

cites work

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Experimental localization of intestinal uptake sites for metals (Cd, Hg, Zn, Se) in vivo in mice

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Methyl mercury uptake across bovine brain capillary endothelial cells in vitro: the role of amino acids

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7 January 2021

Human renal organic anion transporter 1-dependent uptake and toxicity of mercuric-thiol conjugates in Madin-Darby canine kidney cells

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7 January 2021

Na(+)-dependent neutral amino acid transporter ATB(0) is a rabbit epithelial cell brush-border protein

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7 January 2021

Intestinal absorption of dietary cadmium in women depends on body iron stores and fiber intake

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7 January 2021

Differences in cadmium and mercury uptakes by hepatocytes: role of calcium channels

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7 January 2021

Effect of glutathione and cysteine on apical and basolateral uptake and toxicity of CdCl2 in kidney cells (LLC-PK1)

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7 January 2021

Interactions between cadmium and zinc in the organism.

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7 January 2021

Expression of the iron transporter DMT1 in kidney from normal and anemic mk mice

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7 January 2021

Biliary excretion of cadmium in rat. II. The role of metallothionein in the hepatobiliary transport of cadmium

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7 January 2021

Metabolism of orally administered cadmium-metallothionein in mice

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7 January 2021

Biliary excretion of cadmium in rat. III. Effects of chelating agents and change in intracellular thiol content on biliary transport and tissue distribution of cadmium

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7 January 2021

Biliary excretion of cadmium in rat. VI. Mobilization of cadmium from metallothionein by 2,3-dimercaptopropanol

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7 January 2021

Cadmium-metallothionein-induced nephropathy

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7 January 2021

Gastrointestinal absorption and organ distribution of oral cadmium chloride and cadmium-metallothionein in mice

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7 January 2021

Biliary excretion of cadmium in rat. I. Dose-dependent biliary excretion and the form of cadmium in the bile

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7 January 2021

Urinary cadmium elimination as a biomarker of exposure for evaluating a cadmium dietary exposure--biokinetics model.

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7 January 2021

Cadmium Toxicity in Growing Swine

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7 January 2021

Tolerance to cadmium hepatotoxicity by metallothionein and zinc: in vivo and in vitro studies with MT-null mice

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7 January 2021

A novel zinc-regulated human zinc transporter, hZTL1, is localized to the enterocyte apical membrane

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7 January 2021

Understanding renal toxicity of heavy metals

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7 January 2021

Bile secretion of cadmium, silver, zinc and copper in the rat. Involvement of various transport systems

1 reference

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7 January 2021

Renal cadmium deposition and injury as a result of accumulation of cadmium-metallothionein (CdMT) by the proximal convoluted tubules—A light microscopic autoradiography study with 109CdMT

1 reference

https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Effect of dietary cadmium on growth, cadmium absorption and cadmium tissue levels in growing lambs

1 reference

https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Cadmium-induced hepatic and renal injury in chronically exposed rats: likely role of hepatic cadmium-metallothionein in nephrotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Acute exposure to cadmium causes severe liver injury in rats

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https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Time course of cadmium-induced ultrastructural changes in rat liver.

1 reference

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7 January 2021

Cadmium in kidney cortex, liver, and pancreas from Swedish autopsies. Estimation of biological half time in kidney cortex, considering calorie intake and smoking habits

1 reference

https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Evidence for cadmium uptake through Nramp2: metal speciation studies with Caco-2 cells.

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https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Small-intestinal absorption of cadmium and the significance of mucosal metallothionein

1 reference

https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Transport of cadmium across the apical membrane of epithelial cell lines.

1 reference

https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Effects of zinc and copper on cadmium uptake by brush border membrane vesicles

1 reference

https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Bidirectional transport of cadmium across apical membrane of renal epithelial cell lines via H+-antiporter and inorganic anion exchanger.

1 reference

https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

pH-dependent transport of cadmium in rat renal brush border membrane vesicles: cadmium efflux via H+-antiport

1 reference

https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Cadmium uptake from apical membrane of LLC-PK1 cells via inorganic anion exchanger

1 reference

https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Further analysis of cadmium uptake from apical membrane of LLC-PK1 cells via inorganic anion exchanger

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https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Cadmium accumulation and metabolism by rat liver parenchymal cells in primary monolayer culture

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7 January 2021

Development of a priority list of chemical mixtures occurring at 1188 hazardous waste sites, using the HazDat database

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7 January 2021

Fate of cadmium in rat renal tubules: a microinjection study

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7 January 2021

Fate of cadmium in rat renal tubules: a micropuncture study

1 reference

https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Cadmium uptake and induction of metallothionein synthesis in a renal epithelial cell line (LLC-PK1).

1 reference

https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Dietary calcium restriction enhances cadmium-induced metallothionein synthesis in rats

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https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Excretion and retention of cadmium, zinc, and mercury by rabbit kidney

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7 January 2021

Renal tubular transport of cadmium-metallothionein

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7 January 2021

Interactions between metals in rat jejunum: implications on the nature of cadmium uptake

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7 January 2021

On the mechanism of transfer of heavy metals across cell membranes

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https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Transport of toxic heavy metals across cell membranes

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https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Acute cadmium uptake by rabbit kidneys: mechanism and effects

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https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

On the mechanism of nickel absorption in the rat jejunum

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https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Endogenous metallothionein as determinant of intestinal cadmium absorption: a reevaluation

1 reference

https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Effects of vitamin C and iron and cadmium metabolism

1 reference

https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Cadmium and the kidney

1 reference

https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Cadmium Uptake by Kidney Distal Convoluted Tubule Cells

1 reference

https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Altered subcellular distribution of cadmium following cadmium pretreatment: possible mechanism of tolerance to cadmium-induced lethality

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https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Resistance to cadmium-induced hepatotoxicity in immature rats

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https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Induction of hepatic metallothionein in mouse liver following administration of chelating agents

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https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Renal dysfunction in cadmium smelters: relation to in-vivo liver and kidney cadmium concentrations

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https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Hepatic uptake of cadmium and its biliary release as affected by dithioerythritol and glutathione

1 reference

https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Disposition of metals in rats: a comparative study of fecal, urinary, and biliary excretion and tissue distribution of eighteen metals

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https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Dietary iron lowers the intestinal uptake of cadmium-metallothionein in rats

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https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Cadmium accumulation and metallothionein concentrations after 4-week dietary exposure to cadmium chloride or cadmium-metallothionein in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Interaction of dietary Ca, P, Mg, Mn, Cu, Fe, Zn and Se with the accumulation and oral toxicity of cadmium in rats

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https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Drug excretion mediated by a new prototype of polyspecific transporter

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7 January 2021

Cloning and characterization of a mammalian proton-coupled metal-ion transporter

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7 January 2021

Cadmium-induced apoptosis in mouse liver

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7 January 2021

Metallothionein-null mice are more sensitive than wild-type mice to liver injury induced by repeated exposure to cadmium

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7 January 2021

Effects of cadmium on superoxide dismutase and lipid peroxidation in liver and kidney of growing rats: in vivo and in vitro studies

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7 January 2021

Cadmium-bound metallothionein induces apoptosis in rat kidneys, but not in cultured kidney LLC-PK1 cells

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7 January 2021

Expression cloning of a rat liver Na(+)-independent organic anion transporter

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7 January 2021

Early changes in the tissue distribution of cadmium after oral but not intravenous cadmium exposure

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7 January 2021

Oncogenic potential of mouse translation elongation factor-1 delta, a novel cadmium-responsive proto-oncogene

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7 January 2021

Cadmium-induced cell transformation and tumorigenesis are associated with transcriptional activation of c-fos, c-jun and c-myc proto-oncogenes: role of cellular calcium and reactive oxygen species

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7 January 2021

Ferritin--a general metal detoxicant

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7 January 2021

Comparison of cadmium uptakes from apical and basolateral membranes of LLC-PK1 cells

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7 January 2021

Tissue accumulation of cadmium following oral administration to metallothionein-null mice

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7 January 2021

A kinetic model of cadmium metabolism in the human being

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7 January 2021

Alteration of tissue disposition of cadmium by chelating agents

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7 January 2021

Toxicity and distribution of cadmium administered to rats at sublethal doses

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7 January 2021

The relationship of metallothionein to the toxicity of cadmium after prolonged oral administration to rats

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7 January 2021

Blockade of current through single calcium channels by Cd2+, Mg2+, and Ca2+. Voltage and concentration dependence of calcium entry into the pore

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7 January 2021

Distribution of oxidized and reduced forms of glutathione and cysteine in rat plasma.

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7 January 2021

Dosage-dependent disposition of cadmium administered orally to rats

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7 January 2021

Contribution of cigarette smoking to cadmium accumulation in man.

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7 January 2021

Nephrotoxicity of CdCl2 and Cd-metallothionein in cultured rat kidney proximal tubules and LLC-PK1 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Transgenic mice that overexpress metallothionein-I are protected from cadmium lethality and hepatotoxicity.

1 reference

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7 January 2021

Acute CdMT injection is not a good model to study chronic Cd nephropathy: comparison of chronic CdCl2 and CdMT exposure with acute CdMT injection in rats.

1 reference

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7 January 2021

Chronic combined exposure to cadmium and arsenic exacerbates nephrotoxicity, particularly in metallothionein-I/II null mice

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7 January 2021

Metallothionein-null and wild-type mice show similar cadmium absorption and tissue distribution following oral cadmium administration

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7 January 2021

Cadmium found in non-soluble fraction of kidney homogenates and its relation to renal dysfunction after cadmium-cysteine administration

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7 January 2021

Effect of dietary cadmium on tissue distribution of 109cadmium following a single oral dose in young goats

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7 January 2021

Role of intestinal metallothionein in absorption and distribution of orally administered cadmium

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7 January 2021

Tissue distribution of cadmium and nephropathy after administration of cadmium in several chemical forms

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7 January 2021

Tolerance to cadmium cytotoxicity is induced by zinc through non-metallothionein mechanisms as well as metallothionein induction in cultured cells

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https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Comparison of 115m cadmium retention in rats following different routes of administration

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https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

The effect of L-cysteine on the portion-selective uptake of cadmium in the renal proximal tubule

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https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Possible role of hepatic glutathione in transport of methylmercury into mouse kidney

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https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Plasma cadmium-metallothionein, a biological exposure index for cadmium-induced renal dysfunction, based on the mechanism of its action

1 reference

https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

On the Distribution of Cadmium in Blood

1 reference

https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Involvement of DMT1 in uptake of Cd in MDCK cells: role of protein kinase C.

1 reference

https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Pathways in the binding and uptake of ferritin by hepatocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Cadmium-induced testes oxidative damage in rats can be influenced by dietary zinc intake

1 reference

https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Differential effect of N-acetylcysteine on excretion of the metals Hg, Cd, Pb and Au

1 reference

https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Cloning and functional characterization of a mammalian zinc transporter that confers resistance to zinc

1 reference

https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

The autoradiographic localisation of retained orally administered cadmium tracer within Paneth cells of rat duodenum

1 reference

https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Evidence that E-cadherin may be a target for cadmium toxicity in epithelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Surface binding and uptake of cadmium (Cd2+) by LLC-PK1 cells on permeable membrane supports

1 reference

https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Comparison of the cytotoxic effects of cadmium chloride and cadmium-metallothionein in LLC-PK1 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

A proton nuclear magnetic resonance study of the interaction of cadmium with human erythrocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Mechanisms of cadmium-mediated acute hepatotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Cadmium transport and toxicity in isolated perfused segments of the renal proximal tubule

1 reference

https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Lipid peroxidative damage on cadmium exposure and alterations in antioxidant system in rat erythrocytes: a study with relation to time

1 reference

https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Cadmium-induced lipid peroxidation and the status of the antioxidant system in rat tissues

1 reference

https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

State of iron repletion and cadmium tissue accumulation as a function of growth in young rats after oral cadmium exposure

1 reference

https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Oxidative stress as a mechanism of chronic cadmium-induced hepatotoxicity and renal toxicity and protection by antioxidants

1 reference

https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Cadmium uptake by a human hepatic cell line (WRL-68 cells).

1 reference

https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Oxidative mechanisms in the toxicity of metal ions

1 reference

https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Biliary excretion of exogenous cadmium, and endogenous copper and zinc in the Eisai hyperbilirubinuric (EHB) rat with a near absence of biliary glutathione

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https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Gastrointestinal absorption of Cd-metallothionein and cadmium chloride in mice

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https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Studies of zinc transport into brush-border membrane vesicles isolated from pig small intestine

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https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Zinc binding in intestinal brush-border membrane isolated from pig.

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https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

DMT1 gene expression and cadmium absorption in human absorptive enterocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Fate of 109Cd-labeled metallothionein in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Nramp2 expression is associated with pH-dependent iron uptake across the apical membrane of human intestinal Caco-2 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Permeation of barium and cadmium through slowly inactivating calcium channels in cat sensory neurones.

1 reference

https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Localisation of divalent metal transporter 1 (DMT1) to the microvillus membrane of rat duodenal enterocytes in iron deficiency, but to hepatocytes in iron overload

1 reference

https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Macromolecular interactions with cadmium and the effects of zinc, copper, lead, and mercury ions

1 reference

https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Toxicological principles of metal carcinogenesis with special emphasis on cadmium

1 reference

https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

In vivo characterization of renal iron transport in the anaesthetized rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

In vitro percutaneous absorption of cadmium from water and soil into human skin

1 reference

https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Organic anion transport and action of gamma-glutamyl transpeptidase in kidney linked mechanistically to renal tubular uptake of inorganic mercury

1 reference

https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Influence of different degrees of reduced renal mass on the renal and hepatic disposition of administered cadmium

1 reference

https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Basolateral uptake of inorganic mercury in the kidney

1 reference

https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Basolateral uptake of mercuric conjugates of N-acetylcysteine and cysteine in the kidney involves the organic anion transport system

1 reference

https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Evidence for basolateral uptake of cadmium in the kidneys of rats

1 reference

https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Accumulation and handling of inorganic mercury in the kidney after coadministration with glutathione

1 reference

https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Renal disposition of mercury in rats after intravenous injection of inorganic mercury and cysteine

1 reference

https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Pretreatment with p-aminohippurate inhibits the renal uptake and accumulation of injected inorganic mercury in the rat

1 reference

https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Small aliphatic dicarboxylic acids inhibit renal uptake of administered mercury

1 reference

https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Simultaneous coexposure to inorganic mercury and cadmium: a study of the renal and hepatic disposition of mercury and cadmium

1 reference

https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Renal organic anion transport system: a mechanism for the basolateral uptake of mercury-thiol conjugates along the pars recta of the proximal tubule

1 reference

https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Luminal and basolateral mechanisms involved in the renal tubular uptake of inorganic mercury

1 reference

https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Disposition of inorganic mercury following biliary obstruction and chemically induced glutathione depletion: dispositional changes one hour after the intravenous administration of mercuric chloride

1 reference

https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Relationships between alterations in glutathione metabolism and the disposition of inorganic mercury in rats: effects of biliary ligation and chemically induced modulation of glutathione status

1 reference

https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Mercury-metallothionein and the renal accumulation and handling of mercury

1 reference

https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Lack of luminal or basolateral uptake and transepithelial transport of mercury in isolated perfused proximal tubules exposed to mercury-metallothionein

1 reference

https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Advances in understanding the renal transport and toxicity of mercury

1 reference

https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

Duodenal metal-transporter (DMT-1, NRAMP-2) expression in patients with hereditary haemochromatosis

1 reference

https://api.crossref.org/works/10.1016%2FS0041-008X%2802%2900021-2

7 January 2021

10.1016/S0041-008X(02)00021-2

Identifiers

DOI

1 reference

6 August 2017

1 reference