(Q35079588)

6 August 2017

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title

Clinical application of hematopoietic progenitor cell expansion: current status and future prospects (English)

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6 August 2017

Devine SM

1

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6 August 2017

Lazarus HM

series ordinal

2

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6 August 2017

Emerson SG

series ordinal

3

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6 August 2017

language of work or name

English

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publication date

1 February 2003

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Bone Marrow Transplantation

6 August 2017

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6 August 2017

31

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6 August 2017

4

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6 August 2017

241-252

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https://scigraph.springernature.com/pub.10.1038/sj.bmt.1703813

6 August 2017

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cites work

Translating stem and progenitor cell biology to the clinic: barriers and opportunities

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https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

Hematopoietic stem cells for transplantation

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

Survival after transplantation of unrelated donor umbilical cord blood is comparable to that of human leukocyte antigen-matched unrelated donor bone marrow: results of a matched-pair analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

Superior survival associated with transplantation of matched unrelated versus one-antigen-mismatched unrelated or highly human leukocyte antigen-disparate haploidentical family donor marrow grafts for the treatment of hematologic malignancies: estab

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

Current status of umbilical cord blood hematopoietic stem cell transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

Hematopoietic engraftment and survival in adult recipients of umbilical-cord blood from unrelated donors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

Association of CD34 cell dose with hematopoietic recovery, infections, and other outcomes after HLA-identical sibling bone marrow transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

Hematopoiesis on nylon mesh templates. Comparative long-term bone marrow culture and the influence of stromal support cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

Culture perfusion schedules influence the metabolic activity and granulocyte-macrophage colony-stimulating factor production rates of human bone marrow stromal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

Rapid medium perfusion rate significantly increases the productivity and longevity of human bone marrow cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

Thrombopoietin and hematopoietic stem cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

Purification of primitive human hematopoietic cells capable of repopulating immune-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

Self-renewal of primitive human hematopoietic cells (long-term-culture-initiating cells) in vitro and their expansion in defined medium

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

Expansion in vitro of transplantable human cord blood stem cells demonstrated using a quantitative assay of their lympho-myeloid repopulating activity in nonobese diabetic-scid/scid mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

Progress in the development of systems for in vitro expansion of human hematopoietic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

Ex vivo expansion of hematopoietic progenitor cells and mature cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

Self-renewal and differentiation of interleukin-3-dependent multipotent stem cells are modulated by stromal cells and serum factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

Results of MDR-1 vector modification trial indicate that granulocyte/macrophage colony-forming unit cells do not contribute to posttransplant hematopoietic recovery following intensive systemic therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

Phase I trial of retroviral-mediated transfer of the human MDR1 gene as marrow chemoprotection in patients undergoing high-dose chemotherapy and autologous stem-cell transplantation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

Loss of stem cell repopulating ability upon transplantation. Effects of donor age, cell number, and transplantation procedure

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

Hematopoietic cell transplantation in older patients with hematologic malignancies: replacing high-dose cytotoxic therapy with graft-versus-tumor effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

Prompt and durable engraftment in two older adult patients with high risk chronic myelogenous leukemia (CML) using ex vivo expanded and unmanipulated unrelated umbilical cord blood

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

Ontogeny-associated changes in the cytokine responses of primitive human haemopoietic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

Biology of human umbilical cord blood-derived hematopoietic stem/progenitor cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

Umbilical cord blood progeny cells that retain a CD34+ phenotype after ex vivo expansion have less engraftment potential than unexpanded CD34+ cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

Quantitative analysis reveals expansion of human hematopoietic repopulating cells after short-term ex vivo culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

Expansion of human NOD/SCID-repopulating cells by stem cell factor, Flk2/Flt3 ligand, thrombopoietin, IL-6, and soluble IL-6 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

Identification of primitive human hematopoietic cells capable of repopulating NOD/SCID mouse bone marrow: implications for gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

Improved retroviral gene transfer into murine and Rhesus peripheral blood or bone marrow repopulating cells primed in vivo with stem cell factor and granulocyte colony-stimulating factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

Cytokines increase human hemopoietic cell adhesiveness by activation of very late antigen (VLA)-4 and VLA-5 integrins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

Direct adhesion to bone marrow stroma via fibronectin receptors inhibits hematopoietic progenitor proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

Cell cycle activation of hematopoietic progenitor cells increases very late antigen-5-mediated adhesion to fibronectin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

Engraftment of primates with G-CSF mobilized peripheral blood CD34+ progenitor cells expanded in G-CSF, SCF and MGDF decreases the duration and severity of neutropenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

Previously undetected human hematopoietic cell populations with short-term repopulating activity selectively engraft NOD/SCID-beta2 microglobulin-null mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

The fluctuating phenotype of the lymphohematopoietic stem cell with cell cycle transit

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

The early phase of engraftment after murine blood cell transplantation is mediated by hematopoietic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

High doses of purified stem cells cause early hematopoietic recovery in syngeneic and allogeneic hosts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

Transplantation of highly purified CD34+Thy-1+ hematopoietic stem cells in patients with recurrent indolent non-Hodgkin's lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

Transplantation of highly purified CD34+Thy-1+ hematopoietic stem cells in patients with metastatic breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

Umbilical cord blood: an expandable resource

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

The notch ligand jagged-1 represents a novel growth factor of human hematopoietic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

Cellular copper content modulates differentiation and self-renewal in cultures of cord blood-derived CD34+ cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

Hematopoietic expression of HOXB4 is regulated in normal and leukemic stem cells through transcriptional activation of the HOXB4 promoter by upstream stimulating factor (USF)-1 and USF-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

Phenotypic and functional comparison of cultures of marrow-derived mesenchymal stem cells (MSCs) and stromal cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

Multilineage potential of adult human mesenchymal stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

Embryonic stem cell lines derived from human blastocysts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

Hematopoietic colony-forming cells derived from human embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

Avoidance of stimulation improves engraftment of cultured and retrovirally transduced hematopoietic cells in primates

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

Persistent preswitch clonotypic myeloma cells correlate with decreased survival: evidence for isotype switching within the myeloma clone

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

Comparison of outcomes of unrelated bone marrow and umbilical cord blood transplants in children with acute leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

Non-myeloablative transplants for malignant disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

7 January 2021

Treatment of high-risk acute leukemia with T-cell-depleted stem cells from related donors with one fully mismatched HLA haplotype

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

7 January 2021

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

7 January 2021

Donor characteristics as risk factors in recipients after transplantation of bone marrow from unrelated donors: the effect of donor age

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

7 January 2021

Outcomes among 562 recipients of placental-blood transplants from unrelated donors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

7 January 2021

Factors associated with outcome after unrelated marrow transplantation for treatment of acute lymphoblastic leukemia in children

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

7 January 2021

Reconstitution of hematopoiesis after high-dose chemotherapy by autologous progenitor cells generated ex vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

7 January 2021

CD34-positive cells isolated from cryopreserved peripheral-blood progenitor cells can be expanded ex vivo and used for transplantation with little or no toxicity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

7 January 2021

CD34 positive PBPC expanded ex vivo may not provide durable engraftment following myeloablative chemoradiotherapy regimens

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

7 January 2021

Abrogation of post-myeloablative chemotherapy neutropenia by ex-vivo expanded autologous CD34-positive cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

7 January 2021

Hematopoietic recovery of ex vivo perfusion culture expanded bone marrow and unexpanded peripheral blood progenitors after myeloablative chemotherapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

7 January 2021

Ex vivo expansion of bone marrow from breast cancer patients: reduction in tumor cell content through passive purging

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

7 January 2021

Homing and engraftment defects in ex vivo expanded murine hematopoietic cells are associated with downregulation of beta1 integrin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

7 January 2021

Clinical-scale human umbilical cord blood cell expansion in a novel automated perfusion culture system

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

7 January 2021

Transfusions of granulocyte-colony-stimulating factor-mobilized granulocyte components to allogeneic transplant recipients: analysis of kinetics and factors determining posttransfusion neutrophil and platelet counts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

7 January 2021

New directions in allogeneic stem cell transplantation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

7 January 2021

Functional differences between transplantable human hematopoietic stem cells from fetal liver, cord blood, and adult marrow

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

7 January 2021

Dissociation between stem cell phenotype and NOD/SCID repopulating activity in human peripheral blood CD34(+) cells after ex vivo expansion

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

7 January 2021

The CD34(+)CD38(neg) population is significantly increased in haemopoietic cell expansion cultures in serum-free compared to serum-replete conditions: dissociation of phenotype and function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

7 January 2021

Differential homing and engraftment properties of hematopoietic progenitor cells from murine bone marrow, mobilized peripheral blood, and fetal liver

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

7 January 2021

Ex vivo expansion of umbilical cord blood (UCB) CD34(+) cells alters the expression and function of alpha 4 beta 1 and alpha 5 beta 1 integrins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

7 January 2021

Cord blood G(0) CD34+ cells have a thousand-fold higher capacity for generating progenitors in vitro than G(1) CD34+ cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

7 January 2021

Primitive stem cells alone mediate rapid marrow recovery and multilineage engraftment after transplantation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

7 January 2021

Hematopoietic stem cell quiescence maintained by p21cip1/waf1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BMT.1703813

7 January 2021

Identifiers

DOI

10.1038/SJ.BMT.1703813

1 reference

6 August 2017

1 reference