(Q35084723)

6 August 2017

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title

Beyond lipid-lowering: effects of statins on endothelial nitric oxide (English)

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6 August 2017

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Ulrich Laufs

1

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6 August 2017

publication date

18 February 2003

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European Journal of Clinical Pharmacology

6 August 2017

published in

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6 August 2017

volume

58

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6 August 2017

issue

11

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6 August 2017

page(s)

719-731

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https://scigraph.springernature.com/pub.10.1007/s00228-002-0556-0

6 August 2017

exact match

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cites work

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Further evidence for direct vascular actions of statins: effect on endothelial nitric oxide synthase and adhesion molecules

21 January 2018

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Endothelial nitric oxide synthase-dependent cerebral blood flow augmentation by L-arginine after chronic statin treatment

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

1 reference

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21 January 2018

1 reference

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21 January 2018

1 reference

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21 January 2018

1 reference

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A HMG-CoA reductase inhibitor possesses a potent anti-atherosclerotic effect other than serum lipid lowering effects--the relevance of endothelial nitric oxide synthase and superoxide anion scavenging action

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00228-002-0556-0

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21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00228-002-0556-0

Simvastatin and niacin, antioxidant vitamins, or the combination for the prevention of coronary disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00228-002-0556-0

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21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00228-002-0556-0

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21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00228-002-0556-0

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21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00228-002-0556-0

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21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00228-002-0556-0

Dynamic activation of endothelial nitric oxide synthase by Hsp90.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00228-002-0556-0

Hsp90 and caveolin are key targets for the proangiogenic nitric oxide-mediated effects of statins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00228-002-0556-0

Rapid improvement of nitric oxide bioavailability after lipid-lowering therapy with cerivastatin within two weeks.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00228-002-0556-0

Cerivastatin, a hydroxymethylglutaryl coenzyme a reductase inhibitor, improves endothelial function in elderly diabetic patients within 3 days

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00228-002-0556-0

Withdrawal of statins increases event rates in patients with acute coronary syndromes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00228-002-0556-0

Beyond lipids - the role of the endothelium in coronary artery disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00228-002-0556-0

Statins alter smooth muscle cell accumulation and collagen content in established atheroma of watanabe heritable hyperlipidemic rabbits

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00228-002-0556-0

HMG-CoA reductase inhibitors reduce vascular monocyte chemotactic protein-1 expression in early lesions from hypercholesterolemic swine independently of their effect on plasma cholesterol levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00228-002-0556-0

New insights into the pharmacodynamic and pharmacokinetic properties of statins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00228-002-0556-0

Vascular effects of HMG CoA-reductase inhibitors (statins) unrelated to cholesterol lowering: new concepts for cardiovascular disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00228-002-0556-0

Effect of pravastatin on endothelial function in patients with coronary artery disease (cholesterol-independent effect of pravastatin).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00228-002-0556-0

Rapid effects on vascular function after initiation and withdrawal of atorvastatin in healthy, normocholesterolemic men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00228-002-0556-0

Statins reduce inflammation in atheroma of nonhuman primates independent of effects on serum cholesterol

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00228-002-0556-0

Preclinical and clinical pharmacology of Rosuvastatin, a new 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00228-002-0556-0

Drug treatment of lipid disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00228-002-0556-0

Endothelial dysfunction, oxidative stress, and risk of cardiovascular events in patients with coronary artery disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00228-002-0556-0

Additional benefit of vitamin E supplementation to simvastatin therapy on vasoreactivity of the brachial artery of hypercholesterolemic men

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00228-002-0556-0

The effect of cholesterol-lowering and antioxidant therapy on endothelium-dependent coronary vasomotion

21 January 2018

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12 December 2020

Simvastatin, an HMG-coenzyme A reductase inhibitor, improves endothelial function within 1 month

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12 December 2020

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12 December 2020

Atherogenic concentrations of native low-density lipoproteins down-regulate nitric-oxide-synthase mRNA and protein levels in endothelial cells

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12 December 2020

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12 December 2020

Baseline serum cholesterol and treatment effect in the Scandinavian Simvastatin Survival Study (4S)

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12 December 2020

A HMG-CoA reductase inhibitor improved regression of atherosclerosis in the rabbit aorta without affecting serum lipid levels: possible relevance of up-regulation of endothelial NO synthase mRNA

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12 December 2020

Clinical rationale for rosuvastatin, a potent new HMG-CoA reductase inhibitor

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12 December 2020

Pravastatin has cholesterol-lowering independent effects on the artery wall of atherosclerotic monkeys

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12 December 2020

Endothelial nitric oxide synthase is essential for the HMG-CoA reductase inhibitor cerivastatin to promote collateral growth in response to ischemia

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12 December 2020

Restoring vascular nitric oxide formation by l-arginine improves the symptoms of intermittent claudication in patients with peripheral arterial occlusive disease

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12 December 2020

Single LDL apheresis improves endothelium-dependent vasodilatation in hypercholesterolemic humans

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12 December 2020

Peroxynitrite and atherosclerosis

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12 December 2020

Out, damned dot: studies of the NADPH oxidase in atherosclerosis

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12 December 2020

Increased bioavailability of nitric oxide after lipid-lowering therapy in hypercholesterolemic patients: a randomized, placebo-controlled, double-blind study

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12 December 2020

Pravastatin sodium activates endothelial nitric oxide synthase independent of its cholesterol-lowering actions

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12 December 2020

Simvastatin upregulates coronary vascular endothelial nitric oxide production in conscious dogs

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12 December 2020

Selective impairment of nitric oxide dependent vasodilation in young adults with hypercholesterolaemia

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12 December 2020

Simvastatin preserves the ischemic-reperfused myocardium in normocholesterolemic rat hearts

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12 December 2020

Targeting Rho in cardiovascular disease

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12 December 2020

Post-transcriptional regulation of endothelial nitric oxide synthase mRNA stability by Rho GTPase

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12 December 2020

Small, dense low-density lipoprotein particles and coronary heart disease risk: A clear association with uncertain implications

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12 December 2020

Nitric oxide synthesised from L-arginine mediates endothelium dependent dilatation in human veins in vivo

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12 December 2020

Effect of simvastatin on ischemic signs and symptoms in the Scandinavian simvastatin survival study (4S)

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12 December 2020

Treatment of oesophageal rupture

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12 December 2020

Statin-stimulated nitric oxide release from endothelium

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12 December 2020

Influence of pravastatin and plasma lipids on clinical events in the West of Scotland Coronary Prevention Study (WOSCOPS)

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12 December 2020

Oxidized low-density lipoprotein decreases the expression of endothelial nitric oxide synthase

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12 December 2020

Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S)

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12 December 2020

Endogenous nitric oxide inhibits human platelet adhesion to vascular endothelium

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12 December 2020

Endothelium and acute coronary syndromes

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12 December 2020

Nitric oxide regulates monocyte chemotactic protein-1

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12 December 2020

Inhibition of 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase blocks hypoxia-mediated down-regulation of endothelial nitric oxide synthase

1 reference

12 December 2020

Atorvastatin upregulates type III nitric oxide synthase in thrombocytes, decreases platelet activation, and protects from cerebral ischemia in normocholesterolemic mice

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12 December 2020

The AT(1)-type angiotensin receptor in oxidative stress and atherogenesis: part I: oxidative stress and atherogenesis

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12 December 2020

More than cholesterol: the complexity of coronary artery disease

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12 December 2020

Prevention of coronary heart disease in clinical practice. Recommendations of the Second Joint Task Force of European and other Societies on coronary prevention

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12 December 2020

10.1007/S00228-002-0556-0

Identifiers

DOI

1 reference

6 August 2017

1 reference