(Q35087229)

6 August 2017

title

Novel HPMA copolymer-bound constructs for combined tumor and mitochondrial targeting (English)

1 reference

6 August 2017

Vaikunth Cuchelkar

1

1 reference

6 August 2017

Pavla Kopecková

series ordinal

2

1 reference

6 August 2017

Jindrich Kopecek

series ordinal

3

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6 August 2017

language of work or name

English

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publication date

4 September 2008

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6 August 2017

published in

Molecular Pharmaceutics

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6 August 2017

volume

5

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6 August 2017

issue

5

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6 August 2017

page(s)

776-786

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Synthesis and biological evaluation of disulfide-linked HPMA copolymer-mesochlorin e6 conjugates

6 August 2017

cites work

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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Killing efficacy of a new silicon phthalocyanine in human melanoma cells treated with photodynamic therapy by early activation of mitochondrion-mediated apoptosis

8 July 2018

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8 July 2018

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8 July 2018

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Rapid induction of apoptosis in human keratinocytes with the photosensitizer QLT0074 via a direct mitochondrial action

8 July 2018

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The dawning era of polymer therapeutics

8 July 2018

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Ligand-targeted therapeutics in anticancer therapy

8 July 2018

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Mitochondria, the killer organelles and their weapons

8 July 2018

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8 July 2018

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The effects of subcellular localization of N-(2-hydroxypropyl)methacrylamide copolymer-Mce(6) conjugates in a human ovarian carcinoma

8 July 2018

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8 July 2018

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Targeting peptide nucleic acid (PNA) oligomers to mitochondria within cells by conjugation to lipophilic cations: implications for mitochondrial DNA replication, expression and disease

8 July 2018

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HPMA copolymer-anticancer drug conjugates: design, activity, and mechanism of action

8 July 2018

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Mass spectrometric identification of proteins released from mitochondria undergoing permeability transition

8 July 2018

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Peptide nucleic acid delivery to human mitochondria

8 July 2018

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Somatic mutations of the mitochondrial genome in human colorectal tumours

8 July 2018

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HPMA copolymer-anticancer drug-OV-TL16 antibody conjugates. II. Processing in epithelial ovarian carcinoma cells in vitro

8 July 2018

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8 July 2018

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Correlation of subcellular and intratumoral photosensitizer localization with ultrastructural features after photodynamic therapy

8 July 2018

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Mitochondrial metabolite transporters.

8 July 2018

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Disulfide spacer between methotrexate and poly(D-lysine). A probe for exploring the reductive process in endocytosis

8 July 2018

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A leader peptide is sufficient to direct mitochondrial import of a chimeric protein

8 July 2018

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A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs

8 July 2018

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Biosynthesis of delta-aminolevulinic acid and the regulation of heme formation by immature erythroid cells in man

8 July 2018

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The photodegradation of porphyrins in cells can be used to estimate the lifetime of singlet oxygen

8 July 2018

1 reference

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Localization and photodynamic efficacy of two cationic porphyrins varying in charge distributions

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129976

DQAsome-mediated delivery of plasmid DNA toward mitochondria in living cells

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129976

Mitochondria-targeted antioxidants protect Friedreich Ataxia fibroblasts from endogenous oxidative stress more effectively than untargeted antioxidants.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129976

Mechanisms of cytotoxicity in human ovarian carcinoma cells exposed to free Mce6 or HPMA copolymer-Mce6 conjugates

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129976

Targeted delivery of DNA to the mitochondrial compartment via import sequence-conjugated peptide nucleic acid

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129976

Paclitaxel targets mitochondria upstream of caspase activation in intact human neuroblastoma cells.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129976

Somatic mitochondrial DNA (mtDNA) mutations in papillary thyroid carcinomas and differential mtDNA sequence variants in cases with thyroid tumours

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129976

Antitumor effect of adenovirus-mediated Bax gene transfer on p53-sensitive and p53-resistant cancer lines.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129976

Lonidamine triggers apoptosis via a direct, Bcl-2-inhibited effect on the mitochondrial permeability transition pore

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3129976

High incidence of somatic mitochondrial DNA mutations in human ovarian carcinomas

16 November 2018

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12 December 2020

Evidence that bcl-2 is the target of three photosensitizers that induce a rapid apoptotic response

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12 December 2020

Comprehensive scanning of somatic mitochondrial DNA mutations in breast cancer

1 reference

12 December 2020

Cis-aconityl spacer between daunomycin and macromolecular carriers: A model of pH-sensitive linkage releasing drug from a lysosomotropic conjugate

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12 December 2020

Thromboxane synthetase inhibitors (TXSI). Design, synthesis, and evaluation of a novel series of omega-pyridylalkenoic acids

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12 December 2020

DNA-protein conjugates can enter mitochondria via the protein import pathway.

1 reference

12 December 2020

(6-Maleimidocaproyl)hydrazone of doxorubicin--a new derivative for the preparation of immunoconjugates of doxorubicin

1 reference

12 December 2020

Novel mitochondrial DNA deletion found in a renal cell carcinoma

1 reference

12 December 2020

Photodynamic therapy: a mitochondrial inducer of apoptosis

1 reference

12 December 2020

Identifiers

DOI

10.1021/MP800019G

1 reference

6 August 2017

1 reference

6 August 2017

1 reference