(Q35088826)

6 August 2017

title

PK11195 effect on steroidogenesis is not mediated through the translocator protein (TSPO). (English)

1 reference

6 August 2017

Lan N Tu

1

1 reference

6 August 2017

Amy H Zhao

series ordinal

2

1 reference

6 August 2017

Douglas M Stocco

series ordinal

3

1 reference

6 August 2017

Vimal Selvaraj

series ordinal

4

1 reference

6 August 2017

language of work or name

English

0 references

publication date

23 December 2014

1 reference

6 August 2017

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6 August 2017

volume

156

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6 August 2017

issue

3

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6 August 2017

page(s)

1033-1039

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describes a project that uses

6 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4330312/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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1 reference

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Peripheral benzodiazepine receptor/translocator protein global knock-out mice are viable with no effects on steroid hormone biosynthesis.

8 July 2018

1 reference

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Structure of the mitochondrial translocator protein in complex with a diagnostic ligand

8 July 2018

1 reference

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Investigating the interactions of the 18kDa translocator protein and its ligand PK11195 in planar lipid bilayers.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4330312

The role of PBR/TSPO in steroid biosynthesis challenged

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4330312

Translocator protein/peripheral benzodiazepine receptor is not required for steroid hormone biosynthesis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4330312

Developmental expression of translocator protein/peripheral benzodiazepine receptor in reproductive tissues

8 July 2018

1 reference

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Drug ligand-induced activation of translocator protein (TSPO) stimulates steroid production by aged brown Norway rat Leydig cells

8 July 2018

1 reference

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Mechanisms of action of hormone-sensitive lipase in mouse Leydig cells: its role in the regulation of the steroidogenic acute regulatory protein

8 July 2018

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Multiplex genome engineering using CRISPR/Cas systems

8 July 2018

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Translocator protein (Tspo) gene promoter-driven green fluorescent protein synthesis in transgenic mice: an in vivo model to study Tspo transcription

8 July 2018

1 reference

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Mitochondrial protein import and the genesis of steroidogenic mitochondria

8 July 2018

1 reference

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Three-dimensional structure of TspO by electron cryomicroscopy of helical crystals

8 July 2018

1 reference

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Intracellular cholesterol changes induced by translocator protein (18 kDa) TSPO/PBR ligands

8 July 2018

1 reference

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PK11195, a peripheral benzodiazepine receptor (pBR) ligand, broadly blocks drug efflux to chemosensitize leukemia and myeloma cells by a pBR-independent, direct transporter-modulating mechanism

8 July 2018

1 reference

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8 July 2018

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Targeted disruption of the peripheral-type benzodiazepine receptor gene inhibits steroidogenesis in the R2C Leydig tumor cell line

8 July 2018

1 reference

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Targeted disruption of the mouse gene encoding steroidogenic acute regulatory protein provides insights into congenital lipoid adrenal hyperplasia

8 July 2018

1 reference

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Peripheral benzodiazepine receptor in cholesterol transport and steroidogenesis

8 July 2018

1 reference

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The purification, cloning, and expression of a novel luteinizing hormone-induced mitochondrial protein in MA-10 mouse Leydig tumor cells. Characterization of the steroidogenic acute regulatory protein (StAR)

8 July 2018

1 reference

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A sensory transducer homologous to the mammalian peripheral-type benzodiazepine receptor regulates photosynthetic membrane complex formation in Rhodobacter sphaeroides 2.4.1.

8 July 2018

1 reference

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Peripheral benzodiazepine binding sites: Effect of PK 11195, 1-(2-chlorophenyl)-n-methyl-n-(1-methylpropyl)-3-isoquinolinecarboxamide

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4330312

Peripheral benzodiazepine binding sites in heart and their interaction with dipyridamole

8 July 2018

1 reference

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The peripheral-type benzodiazepine receptor. Localization to the mitochondrial outer membrane.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4330312

Mitochondrial benzodiazepine receptors regulate steroid biosynthesis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4330312

The peripheral-type benzodiazepine receptor is functionally linked to Leydig cell steroidogenesis.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4330312

High densities of benzodiazepine receptors in human cortical areas

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4330312

Specific benzodiazepine receptors in rat brain characterized by high-affinity (3H)diazepam binding

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4330312

PK11195 inhibits mitophagy targeting the F1Fo-ATPsynthase in Bcl-2 knock-down cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4330312

Secondary and tertiary structures of the transmembrane domains of the translocator protein TSPO determined by NMR. Stabilization of the TSPO tertiary fold upon ligand binding

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4330312

PK11195 potently sensitizes to apoptosis induction independently from the peripheral benzodiazepin receptor

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4330312

Peripheral benzodiazepine receptor (PBR) ligand cytotoxicity unrelated to PBR expression

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4330312

Peripheral-type benzodiazepine receptor (PBR) and PBR drug ligands in fibroblast and fibrosarcoma cell proliferation: role of ERK, c-Jun and ligand-activated PBR-independent pathways

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4330312

Peripheral-type benzodiazepine receptors: autoradiographic localization in whole-body sections of neonatal rats.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4330312

On the role of the translocator protein (18-kDa) TSPO in steroid hormone biosynthesis

27 September 2018

1 reference

12 December 2020

High affinity renal [3H]flunitrazepam binding: Characterization, localization, and alteration in hypertension

1 reference

12 December 2020

Factors underlying the variability of lipid droplet fluorescence in MA-10 Leydig tumor cells

1 reference

12 December 2020

Peripheral-type benzodiazepine receptor function in cholesterol transport. Identification of a putative cholesterol recognition/interaction amino acid sequence and consensus pattern

1 reference

12 December 2020

Identifiers

DOI

10.1210/EN.2014-1707

1 reference

6 August 2017

1 reference

6 August 2017

1 reference