(Q35094477)

English

Matrix contraction by dermal fibroblasts requires transforming growth factor-beta/activin-linked kinase 5, heparan sulfate-containing proteoglycans, and MEK/ERK: insights into pathological scarring in chronic fibrotic disease

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scholarly article

1 reference

Europe PubMed Central

6 August 2017

Matrix contraction by dermal fibroblasts requires transforming growth factor-beta/activin-linked kinase 5, heparan sulfate-containing proteoglycans, and MEK/ERK: insights into pathological scarring in chronic fibrotic disease (English)

1 reference

Europe PubMed Central

6 August 2017

author name string

Yunliang Chen

1

1 reference

Europe PubMed Central

6 August 2017

Xu Shi-Wen

2

1 reference

Europe PubMed Central

6 August 2017

Jonathan van Beek

3

1 reference

Europe PubMed Central

6 August 2017

Laura Kennedy

4

1 reference

Europe PubMed Central

6 August 2017

Marilyn McLeod

5

1 reference

Europe PubMed Central

6 August 2017

Elisabetta A Renzoni

6

1 reference

Europe PubMed Central

6 August 2017

George Bou-Gharios

7

1 reference

Europe PubMed Central

6 August 2017

Sarah Wilcox-Adelman

8

1 reference

Europe PubMed Central

6 August 2017

Paul F Goetinck

9

1 reference

Europe PubMed Central

6 August 2017

Mark Eastwood

10

1 reference

Europe PubMed Central

6 August 2017

Carol M Black

11

1 reference

Europe PubMed Central

6 August 2017

David J Abraham

12

1 reference

Europe PubMed Central

6 August 2017

Andrew Leask

13

1 reference

Europe PubMed Central

6 August 2017

language of work or name

0 references

publication date

1 December 2005

1 reference

Europe PubMed Central

6 August 2017

The American Journal of Pathology

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Europe PubMed Central

6 August 2017

167

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Europe PubMed Central

6 August 2017

1699-1711

1 reference

Europe PubMed Central

6 August 2017

6

1 reference

Europe PubMed Central

6 August 2017

Gene expression profiling reveals novel TGFbeta targets in adult lung fibroblasts

1 reference

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9 July 2018

CCN2 (connective tissue growth factor) promotes fibroblast adhesion to fibronectin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1613194

9 July 2018

Syndecans-2 and -4; close cousins, but not identical twins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1613194

9 July 2018

TGF-beta signaling and the fibrotic response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1613194

9 July 2018

Endothelin-1 promotes myofibroblast induction through the ETA receptor via a rac/phosphoinositide 3-kinase/Akt-dependent pathway and is essential for the enhanced contractile phenotype of fibrotic fibroblasts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1613194

9 July 2018

Endothelin-1 induces expression of matrix-associated genes in lung fibroblasts through MEK/ERK.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1613194

9 July 2018

Insights into the molecular mechanism of chronic fibrosis: the role of connective tissue growth factor in scleroderma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1613194

9 July 2018

CCN proteins: multifunctional signalling regulators

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1613194

9 July 2018

Mechanisms of force generation and transmission by myofibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1613194

9 July 2018

Systemic and cell type-specific gene expression patterns in scleroderma skin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1613194

9 July 2018

The myofibroblast in wound healing and fibrocontractive diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1613194

9 July 2018

Regulation of cytoskeletal organization by syndecan transmembrane proteoglycans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1613194

9 July 2018

Connective tissue growth factor gene regulation. Requirements for its induction by transforming growth factor-beta 2 in fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1613194

9 July 2018

CTGF expression in mesangial cells: involvement of SMADs, MAP kinase, and PKC.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1613194

9 July 2018

Modulation of the Ras/Raf/MEK/ERK pathway by Ca(2+), and calmodulin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1613194

9 July 2018

Myofibroblasts and mechano-regulation of connective tissue remodelling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1613194

9 July 2018

Paxillin: a focal adhesion-associated adaptor protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1613194

9 July 2018

Iloprost suppresses connective tissue growth factor production in fibroblasts and in the skin of scleroderma patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1613194

9 July 2018

Delayed wound repair and impaired angiogenesis in mice lacking syndecan-4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1613194

9 July 2018

Autocrine overexpression of CTGF maintains fibrosis: RDA analysis of fibrosis genes in systemic sclerosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1613194

9 July 2018

Tumor necrosis factor alpha suppresses the induction of connective tissue growth factor by transforming growth factor-beta in normal and scleroderma fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1613194

9 July 2018

Control of morphology, cytoskeleton and migration by syndecan-4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1613194

9 July 2018

Role and interaction of connective tissue growth factor with transforming growth factor-beta in persistent fibrosis: A mouse fibrosis model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1613194

9 July 2018

Connective tissue growth factor: a mediator of TGF-beta action on fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1613194

9 July 2018

Heparan sulphate proteoglycan and wound healing in skin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1613194

9 July 2018

Hypothesis for the pathogenesis of systemic sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1613194

9 July 2018

Pathogenesis of scleroderma. Collagen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1613194

9 July 2018

Scleroderma--clinical aspects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1613194

9 July 2018

Spatial and temporal changes in the expression of fibroglycan (syndecan-2) during mouse embryonic development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1613194

9 July 2018

Increased collagen synthesis by scleroderma skin fibroblasts in vitro: a possible defect in the regulation or activation of the scleroderma fibroblast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1613194

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Xyloside inhibits synthesis of the class II-associated chondroitin sulfate proteoglycan and antigen presentation events

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1613194

9 July 2018

Immunological mediators of wound healing and fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1613194

9 July 2018

Effects of inhibition of proteoglycan synthesis on the differentiation of cultured rat Schwann cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1613194

9 July 2018

Regulatory mechanisms of fibroblast activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1613194

9 July 2018

Inhibition of proteoglycan synthesis alters extracellular matrix deposition, proliferation, and cytoskeletal organization of rat aortic smooth muscle cells in culture

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1613194

9 July 2018

Heparan sulfate proteoglycans and signalling in cell adhesion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1613194

9 July 2018

Progressive transforming growth factor beta1-induced lung fibrosis is blocked by an orally active ALK5 kinase inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1613194

27 September 2018

Syndecan-4 regulates ATF-2 transcriptional activity in a Rac1-dependent manner

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1613194

27 September 2018

An increased transforming growth factor beta receptor type I:type II ratio contributes to elevated collagen protein synthesis that is resistant to inhibition via a kinase-deficient transforming growth factor beta receptor type II in scleroderma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1613194

27 September 2018

Prostacyclin derivatives prevent the fibrotic response to TGF-beta by inhibiting the Ras/MEK/ERK pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1613194

27 September 2018

Dysregulation of transforming growth factor beta signaling in scleroderma: overexpression of endoglin in cutaneous scleroderma fibroblasts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1613194

27 September 2018

Syndecan-4 modulates focal adhesion kinase phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1613194

27 September 2018

CTGF and SMADs, maintenance of scleroderma phenotype is independent of SMAD signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1613194

27 September 2018

Elevated pro alpha 2(I) collagen mRNA levels in cultured scleroderma fibroblasts result from an increased transcription rate of the corresponding gene

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2961252-7

7 January 2021

Differences in the regulation of fibroblast contraction of floating versus stressed collagen matrices

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2961252-7

7 January 2021

Constitutive connective tissue growth factor expression in scleroderma fibroblasts is dependent on Sp1

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2961252-7

7 January 2021

Syndecans-1 and -4 are induced during wound repair of neonatal but not fetal skin

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2961252-7

7 January 2021

Expression of TGF-beta 1, -beta 2 and -beta 3 in localized and systemic scleroderma

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2961252-7

7 January 2021

Expression and regulation of intracellular SMAD signaling in scleroderma skin fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2961252-7

7 January 2021

Myofibroblast differentiation during fibrosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16314481

12 December 2020

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10.1016/S0002-9440(10)61252-7

1 reference

Europe PubMed Central

6 August 2017

1 reference

Europe PubMed Central

6 August 2017

1 reference

Europe PubMed Central

6 August 2017

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