(Q35101152)

English

An adaptive, phase II, dose-finding clinical trial design to evaluate L-carnitine in the treatment of septic shock based on efficacy and predictive probability of subsequent phase III success

scientific article

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scholarly article

1 reference

Europe PubMed Central

6 August 2017

An adaptive, phase II, dose-finding clinical trial design to evaluate L-carnitine in the treatment of septic shock based on efficacy and predictive probability of subsequent phase III success (English)

1 reference

Europe PubMed Central

6 August 2017

phase III clinical trial

0 references

phase II clinical trial

0 references

0 references

1 reference

based on heuristic

inferred from title

author name string

Roger J Lewis

1

1 reference

Europe PubMed Central

6 August 2017

Kert Viele

2

1 reference

Europe PubMed Central

6 August 2017

Kristine Broglio

3

1 reference

Europe PubMed Central

6 August 2017

Scott M Berry

4

1 reference

Europe PubMed Central

6 August 2017

Alan E Jones

5

1 reference

Europe PubMed Central

6 August 2017

language of work or name

0 references

publication date

1 July 2013

1 reference

Europe PubMed Central

6 August 2017

Critical Care Medicine

1 reference

Europe PubMed Central

6 August 2017

41

1 reference

Europe PubMed Central

6 August 2017

7

1 reference

Europe PubMed Central

6 August 2017

1674-1678

1 reference

Europe PubMed Central

6 August 2017

Improving clinical trials in the critically ill.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4334380

9 July 2018

Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4334380

9 July 2018

Endpoints in sepsis trials: more than just 28-day mortality?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4334380

9 July 2018

Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4334380

9 July 2018

The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure. On behalf of the Working Group on Sepsis-Related Problems of the European Society of Intensive Care Medicine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4334380

9 July 2018

Increase in National Hospital Discharge Survey rates for septicemia--United States, 1979-1987.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4334380

9 July 2018

A Bayesian dose-finding trial with adaptive dose expansion to flexibly assess efficacy and safety of an investigational drug

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4334380

27 September 2018

Innovative Approaches for Designing and Analyzing Adaptive Dose-Ranging Trials

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4334380

8 December 2018

Adaptive designs in clinical drug development--an Executive Summary of the PhRMA Working Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/23514753

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1097/CCM.0B013E318287F850

1 reference

Europe PubMed Central

6 August 2017

1 reference

Europe PubMed Central

6 August 2017

1 reference

Europe PubMed Central

6 August 2017

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