(Q35102889)

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Inhibition of vascular endothelial growth factor (VEGF) signaling in cancer causes loss of endothelial fenestrations, regression of tumor vessels, and appearance of basement membrane ghosts

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scholarly article

1 reference

Europe PubMed Central

6 August 2017

Inhibition of vascular endothelial growth factor (VEGF) signaling in cancer causes loss of endothelial fenestrations, regression of tumor vessels, and appearance of basement membrane ghosts (English)

1 reference

Europe PubMed Central

6 August 2017

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author name string

Tetsuichiro Inai

1

1 reference

Europe PubMed Central

6 August 2017

Michael Mancuso

2

1 reference

Europe PubMed Central

6 August 2017

Hiroya Hashizume

3

1 reference

Europe PubMed Central

6 August 2017

Fabienne Baffert

4

1 reference

Europe PubMed Central

6 August 2017

Amy Haskell

5

1 reference

Europe PubMed Central

6 August 2017

Peter Baluk

6

1 reference

Europe PubMed Central

6 August 2017

Dana D Hu-Lowe

7

1 reference

Europe PubMed Central

6 August 2017

David R Shalinsky

8

1 reference

Europe PubMed Central

6 August 2017

Gavin Thurston

9

1 reference

Europe PubMed Central

6 August 2017

George D Yancopoulos

10

1 reference

Europe PubMed Central

6 August 2017

Donald M McDonald

11

1 reference

Europe PubMed Central

6 August 2017

language of work or name

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publication date

1 July 2004

1 reference

Europe PubMed Central

6 August 2017

The American Journal of Pathology

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Europe PubMed Central

6 August 2017

165

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Europe PubMed Central

6 August 2017

35-52

1 reference

Europe PubMed Central

6 August 2017

1

1 reference

Europe PubMed Central

6 August 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC1618540/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Abnormalities of Basement Membrane on Blood Vessels and Endothelial Sprouts in Tumors

1 reference

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9 July 2018

A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer

1 reference

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9 July 2018

Endothelial-pericyte interactions in angiogenesis.

1 reference

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9 July 2018

Regression of established tumors and metastases by potent vascular endothelial growth factor blockade

1 reference

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Antiangiogenesis drug promising for metastatic colorectal cancer

1 reference

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9 July 2018

The biology of VEGF and its receptors

1 reference

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Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors

1 reference

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Role of vascular endothelial growth factor in physiologic and pathologic angiogenesis: therapeutic implications

1 reference

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Adenovirus-mediated delivery of a soluble form of the VEGF receptor Flk1 delays the growth of murine and human pancreatic adenocarcinoma in mice

1 reference

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Development of biologic markers of response and assessment of antiangiogenic activity in a clinical trial of human recombinant endostatin

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VEGF-Trap: a VEGF blocker with potent antitumor effects

1 reference

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Clinical application of antiangiogenic therapy: microvessel density, what it does and doesn't tell us.

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9 July 2018

Abnormalities in pericytes on blood vessels and endothelial sprouts in tumors

1 reference

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9 July 2018

Analysis of mural cell recruitment to tumor vessels

1 reference

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9 July 2018

Normalizing tumor vasculature with anti-angiogenic therapy: a new paradigm for combination therapy

1 reference

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9 July 2018

Lack of pericytes leads to endothelial hyperplasia and abnormal vascular morphogenesis

1 reference

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9 July 2018

Endothelial cells of tumor vessels: abnormal but not absent.

1 reference

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Gene therapy-mediated expression by tumor cells of the angiogenesis inhibitor flk-1 results in inhibition of neuroblastoma growth in vivo

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Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis

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Genes expressed in human tumor endothelium

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Openings between defective endothelial cells explain tumor vessel leakiness

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Effects of angiogenesis inhibitors on multistage carcinogenesis in mice

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Selective ablation of immature blood vessels in established human tumors follows vascular endothelial growth factor withdrawal

1 reference

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SU5416 is a potent and selective inhibitor of the vascular endothelial growth factor receptor (Flk-1/KDR) that inhibits tyrosine kinase catalysis, tumor vascularization, and growth of multiple tumor types

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Monoclonal antibodies targeting the VEGF receptor-2 (Flk1/KDR) as an anti-angiogenic therapeutic strategy

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Paracrine expression of a native soluble vascular endothelial growth factor receptor inhibits tumor growth, metastasis, and mortality rate

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Solution structure of the heparin-binding domain of vascular endothelial growth factor

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Conditional switching of vascular endothelial growth factor (VEGF) expression in tumors: induction of endothelial cell shedding and regression of hemangioblastoma-like vessels by VEGF withdrawal

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Time-dependent vascular regression and permeability changes in established human tumor xenografts induced by an anti-vascular endothelial growth factor/vascular permeability factor antibody

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Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutant

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Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo

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Intratumor microvessel density as a prognostic factor in cancer

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Basal lamina scaffold-anatomy and significance for maintenance of orderly tissue structure

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Age-related changes in vascular endothelial growth factor dependency and angiopoietin-1-induced plasticity of adult blood vessels

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Combined inhibition of VEGF and PDGF signaling enforces tumor vessel regression by interfering with pericyte-mediated endothelial cell survival mechanisms

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Antiangiogenic Therapy: More Promise and, Yet Again, More Questions

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Role of VEGF-A in vascularization of pancreatic islets

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PTK787/ZK 222584, a specific vascular endothelial growth factor-receptor tyrosine kinase inhibitor, affects the anatomy of the tumor vascular bed and the functional vascular properties as detected by dynamic enhanced magnetic resonance imaging.

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VEGF deprivation-induced apoptosis is a component of programmed capillary regression.

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Fluid shear stress stimulates phosphorylation of Akt in human endothelial cells: involvement in suppression of apoptosis

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https://pubmed.ncbi.nlm.nih.gov/15215160

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Vascular endothelial growth factor is an in vivo survival factor for tumor endothelium in a murine model of colorectal carcinoma liver metastases

1 reference

https://pubmed.ncbi.nlm.nih.gov/15215160

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based on heuristic

inferred from PubMed ID database lookup

Regression of the tunica vasculosa lentis in the postnatal rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/15215160

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based on heuristic

inferred from PubMed ID database lookup

A relationship between apoptosis and flow during programmed capillary regression is revealed by vital analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15215160

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/S0002-9440(10)63273-7

1 reference

Europe PubMed Central

6 August 2017

1 reference

Europe PubMed Central

6 August 2017

1 reference

Europe PubMed Central

6 August 2017

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