(Q35102984)

6 August 2017

title

B Lymphocyte signaling established by the CD19/CD22 loop regulates autoimmunity in the tight-skin mouse (English)

1 reference

6 August 2017

Noriko Asano

1

1 reference

6 August 2017

Manabu Fujimoto

2

1 reference

6 August 2017

Norihito Yazawa

3

1 reference

6 August 2017

Senji Shirasawa

4

1 reference

6 August 2017

Minoru Hasegawa

5

1 reference

6 August 2017

Hitoshi Okochi

6

1 reference

6 August 2017

Kunihiko Tamaki

7

1 reference

6 August 2017

Thomas F Tedder

8

1 reference

6 August 2017

Shinichi Sato

9

1 reference

6 August 2017

language of work or name

English

0 references

publication date

1 August 2004

1 reference

The American Journal of Pathology

6 August 2017

published in

1 reference

6 August 2017

volume

165

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6 August 2017

issue

2

1 reference

6 August 2017

page(s)

641-650

1 reference

CD19-dependent B lymphocyte signaling thresholds influence skin fibrosis and autoimmunity in the tight-skin mouse

6 August 2017

cites work

1 reference

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Complementary roles for CD19 and Bruton's tyrosine kinase in B lymphocyte signal transduction

9 July 2018

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The ligand-binding domain of CD22 is needed for inhibition of the B cell receptor signal, as demonstrated by a novel human CD22-specific inhibitor compound.

9 July 2018

1 reference

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Sialic acid binding domains of CD22 are required for negative regulation of B cell receptor signaling

9 July 2018

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Interleukin 4 reduces expression of inhibitory receptors on B cells and abolishes CD22 and Fc gamma RII-mediated B cell suppression.

9 July 2018

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Disrupting the IL-4 gene rescues mice homozygous for the tight-skin mutation from embryonic death and diminishes TGF-beta production by fibroblasts

9 July 2018

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B cell receptor signaling and autoimmunity.

9 July 2018

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CD22 regulates B cell receptor-mediated signals via two domains that independently recruit Grb2 and SHP-1

9 July 2018

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9 July 2018

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9 July 2018

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Lack of skin fibrosis in tight skin (TSK) mice with targeted mutation in the interleukin-4R alpha and transforming growth factor-beta genes.

9 July 2018

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Genetic and immunologic features associated with scleroderma-like syndrome of TSK mice

9 July 2018

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Identification of CD72 as a Lymphocyte Receptor for the Class IV Semaphorin CD100

9 July 2018

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CD19 and CD22 regulate a B lymphocyte signal transduction pathway that contributes to autoimmunity

9 July 2018

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CD22 forms a quaternary complex with SHIP, Grb2, and Shc. A pathway for regulation of B lymphocyte antigen receptor-induced calcium flux

9 July 2018

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9 July 2018

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A novel mouse with B cells but lacking serum antibody reveals an antibody-independent role for B cells in murine lupus

9 July 2018

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From systemic T cell self-reactivity to organ-specific autoimmune disease via immunoglobulins

9 July 2018

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Masking and unmasking of the sialic acid-binding lectin activity of CD22 (Siglec-2) on B lymphocytes

9 July 2018

1 reference

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Polygenic autoimmune traits: Lyn, CD22, and SHP-1 are limiting elements of a biochemical pathway regulating BCR signaling and selection

9 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618564

The Tight skin mouse: demonstration of mutant fibrillin-1 production and assembly into abnormal microfibrils.

9 July 2018

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The motheaten mutation rescues B cell signaling and development in CD45-deficient mice

9 July 2018

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CD22 is a negative regulator of B-cell receptor signalling

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618564

CD22 regulates thymus-independent responses and the lifespan of B cells.

9 July 2018

1 reference

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B cells from patients with systemic lupus erythematosus display abnormal antigen receptor-mediated early signal transduction events

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618564

Antinuclear antibody in systemic sclerosis (scleroderma).

9 July 2018

1 reference

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Hyperresponsive B cells in CD22-deficient mice

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618564

Organization of the murine Cd22 locus. Mapping to chromosome 7 and characterization of two alleles.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618564

Autoantibodies in scleroderma and tightskin mice

9 July 2018

1 reference

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Regulation of connective tissue synthesis in systemic sclerosis.

9 July 2018

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Tissue-specific expression of the human CD19 gene in transgenic mice inhibits antigen-independent B-lymphocyte development.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618564

Clinical correlations and prognosis based on serum autoantibodies in patients with systemic sclerosis

9 July 2018

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CD19: lowering the threshold for antigen receptor stimulation of B lymphocytes

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618564

Tight-skin, a new mutation of the mouse causing excessive growth of connective tissue and skeleton

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618564

An open study of B lymphocyte depletion in systemic lupus erythematosus

9 July 2018

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Efficacy of selective B cell blockade in the treatment of rheumatoid arthritis: evidence for a pathogenetic role of B cells

27 September 2018

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Expression of B cell receptor-associated signaling molecules in human lupus

27 September 2018

1 reference

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Clinical significance of anti-topoisomerase I antibody levels determined by ELISA in systemic sclerosis.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618564

CD19 amplification of B lymphocyte Ca2+ responses: a role for Lyn sequestration in extinguishing negative regulation

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618564

Dysregulated expression of the Cd22 gene as a result of a short interspersed nucleotide element insertion in Cd22a lupus-prone mice.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618564

Polymorphisms in the Cd22 gene of inbred mouse strains.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618564

CD22 is both a positive and negative regulator of B lymphocyte antigen receptor signal transduction: altered signaling in CD22-deficient mice.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618564

Correlates between autoantibodies to nucleolar antigens and clinical features in patients with systemic sclerosis (scleroderma)

27 September 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963328-7

Modulation of B lymphocyte antigen receptor signal transduction by a CD19/CD22 regulatory loop

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963328-7

Quantitative genetic variation in CD19 expression correlates with autoimmunity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963328-7

Correlation of serum anti‐DNA topoisomerase I antibody levels with disease severity and activity in systemic sclerosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963328-7

Functional soluble CD100/Sema4D released from activated lymphocytes: possible role in normal and pathologic immune responses

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963328-7

B-cell deficiency does not abrogate development of cutaneous hyperplasia in mice inheriting the defective fibrillin-1 gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963328-7

Induction of skin fibrosis and autoantibodies by infusion of immunocompetent cells from tight skin mice into C57BL/6 Pa/Pa mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963328-7

B-cell kinase lyn deficiency in patients with systemic lupus erythematosus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963328-7

CD19 expression levels regulate B lymphocyte development: human CD19 restores normal function in mice lacking endogenous CD19

7 January 2021

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12 December 2020

Functional dissection of systemic lupus erythematosus using congenic mouse strains

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12 December 2020

Role of the CD22 human B cell antigen in B cell triggering by anti-immunoglobulin

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12 December 2020

Scleroderma (systemic sclerosis): classification, subsets and pathogenesis

1 reference

12 December 2020

Identification of CD72 as a lymphocyte receptor for the class IV semaphorin CD100: a novel mechanism for regulating B cell signaling

1 reference

12 December 2020

10.1016/S0002-9440(10)63328-7

Identifiers

DOI

1 reference

6 August 2017

1 reference

6 August 2017

1 reference