(Q35103078)

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Cerebral expression of interleukin-12 induces neurological disease via differential pathways and recruits antigen-specific T cells in virus-infected mice

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Europe PubMed Central

PubMed publication ID

6 August 2017

Cerebral expression of interleukin-12 induces neurological disease via differential pathways and recruits antigen-specific T cells in virus-infected mice (English)

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

author name string

Markus Hofer

1

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Jürgen Hausmann

2

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Peter Staeheli

3

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Axel Pagenstecher

4

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

language of work or name

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publication date

1 September 2004

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Europe PubMed Central

PubMed publication ID

6 August 2017

The American Journal of Pathology

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Europe PubMed Central

PubMed publication ID

6 August 2017

165

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

3

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

949-958

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Borna disease virus multiplication in mouse organotypic slice cultures is site-specifically inhibited by gamma interferon but not by interleukin-12.

1 reference

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9 July 2018

Gamma interferon is critical for neuronal viral clearance and protection in a susceptible mouse strain following early intracranial Theiler's murine encephalomyelitis virus infection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618590

9 July 2018

Interleukin-12 and the regulation of innate resistance and adaptive immunity

1 reference

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9 July 2018

STAT1 deficiency unexpectedly and markedly exacerbates the pathophysiological actions of IFN-alpha in the central nervous system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618590

9 July 2018

Bornavirus and the brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618590

9 July 2018

Borna disease virus accelerates inflammation and disease associated with transgenic expression of interleukin-12 in the central nervous system

1 reference

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The danger model: a renewed sense of self

1 reference

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9 July 2018

Immune-mediated protection from measles virus-induced central nervous system disease is noncytolytic and gamma interferon dependent

1 reference

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9 July 2018

1 reference

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9 July 2018

The immunopathogenesis of Borna disease virus infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618590

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Role of nitric oxide in murine cytomegalovirus (MCMV) infection

1 reference

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9 July 2018

Identification of the immunodominant H-2K(k)-restricted cytotoxic T-cell epitope in the Borna disease virus nucleoprotein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618590

9 July 2018

Chemokine gene expression in astrocytes of Borna disease virus-infected rats and mice in the absence of inflammation

1 reference

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9 July 2018

Epidemiology of Borna disease virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618590

9 July 2018

Initial and innate responses to viral infections--pattern setting in immunity or disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618590

9 July 2018

T cell ignorance in mice to Borna disease virus can be overcome by peripheral expression of the viral nucleoprotein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618590

9 July 2018

Leukocyte traffic in the central nervous system: the participants and their roles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618590

9 July 2018

Borna disease virus nucleoprotein (p40) is a major target for CD8(+)-T-cell-mediated immune response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618590

9 July 2018

T-cell apoptosis in inflammatory brain lesions: destruction of T cells does not depend on antigen recognition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618590

9 July 2018

The interleukin-12/interleukin-12-receptor system: role in normal and pathologic immune responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618590

9 July 2018

Borna disease virus-induced neurological disorder in mice: infection of neonates results in immunopathology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618590

9 July 2018

RNAse protection assays for the simultaneous and semiquantitative analysis of multiple murine matrix metalloproteinase (MMP) and MMP inhibitor mRNAs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618590

9 July 2018

Primary demyelination in transgenic mice expressing interferon-gamma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618590

9 July 2018

Lipopolysaccharide-induced IL-12 expression in the central nervous system and cultured astrocytes and microglia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618590

9 July 2018

Increased interleukin 12 production in progressive multiple sclerosis: induction by activated CD4+ T cells via CD40 ligand

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618590

9 July 2018

Activation of STAT4 by IL-12 and IFN-alpha: evidence for the involvement of ligand-induced tyrosine and serine phosphorylation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618590

9 July 2018

Interferon-gamma induced type I nitric oxide synthase activity inhibits viral replication in neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618590

9 July 2018

The molecular cell biology of interferon-gamma and its receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618590

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Apoptosis of T lymphocytes in experimental autoimmune encephalomyelitis. Evidence for programmed cell death as a mechanism to control inflammation in the brain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618590

9 July 2018

Disseminated tuberculosis in interferon gamma gene-disrupted mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618590

9 July 2018

Interleukin-12 and its role in the generation of TH1 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618590

9 July 2018

Natural killer cell stimulatory factor (interleukin 12 [IL-12]) induces T helper type 1 (Th1)-specific immune responses and inhibits the development of IL-4-producing Th cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618590

9 July 2018

Gamma interferon is a major mediator of antiviral defense in experimental measles virus-induced encephalitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618590

9 July 2018

Expression of costimulatory molecules B7-1 (CD80), B7-2 (CD86), and interleukin 12 cytokine in multiple sclerosis lesions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618590

9 July 2018

The in vivo antiviral activity of interleukin-12 is mediated by gamma interferon

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618590

9 July 2018

Clinical viral infections and multiple sclerosis.

1 reference

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9 July 2018

Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins

1 reference

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9 July 2018

Isolation of brain parenchymal lymphocytes for flow cytometric analysis. Application to acute viral encephalitis

1 reference

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Inflammatory cytokines within the central nervous system: sources, function, and mechanism of action

1 reference

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9 July 2018

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

1 reference

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618590

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Upregulation of chemokine receptor gene expression in brains of Borna disease virus (BDV)-infected rats in the absence and presence of inflammation

1 reference

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27 September 2018

Induction of type 1 immune pathology in the brain following immunization without central nervous system autoantigen in transgenic mice with astrocyte-targeted expression of IL-12.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618590

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Interferon-gamma-mediated site-specific clearance of alphavirus from CNS neurons

1 reference

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27 September 2018

Regional hypomyelination and dysplasia in transgenic mice with astrocyte-directed expression of interferon-gamma.

1 reference

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Regulation of the BBB during viral encephalitis: roles of IL-12 and NOS.

1 reference

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Transgenic expression of IFN-alpha in the central nervous system of mice protects against lethal neurotropic viral infection but induces inflammation and neurodegeneration.

1 reference

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Induction of IL-12 gene expression in the brain in septic shock

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25 October 2018

IL-12 stimulates an antiviral type 1 cytokine response but lacks adjuvant activity in IFN-gamma-receptor-deficient mice

1 reference

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25 October 2018

Interleukin-12: a cytokine at the interface of inflammation and immunity

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Interleukin-12 promotes recovery from viral encephalitis

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https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963356-1

7 January 2021

Astrocyte-targeted expression of IL-12 induces active cellular immune responses in the central nervous system and modulates experimental allergic encephalomyelitis.

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963356-1

7 January 2021

Targeted CNS expression of interferon-gamma in transgenic mice leads to hypomyelination, reactive gliosis, and abnormal cerebellar development

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https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963356-1

7 January 2021

Influence of infection on exacerbations of multiple sclerosis

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7 January 2021

Synergism for cytokine-mediated disease during concurrent endotoxin and viral challenges: roles for NK and T cell IFN-gamma production

1 reference

https://pubmed.ncbi.nlm.nih.gov/15331418

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Roles of IFN-gamma and IFN-alpha in IL-12-induced T helper cell-1 development

1 reference

https://pubmed.ncbi.nlm.nih.gov/15331418

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/S0002-9440(10)63356-1

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

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