(Q35103873)

English

Phospho-aspirin (MDC-22) inhibits breast cancer in preclinical animal models: an effect mediated by EGFR inhibition, p53 acetylation and oxidative stress

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scholarly article

1 reference

Europe PubMed Central

6 August 2017

Phospho-aspirin (MDC-22) inhibits breast cancer in preclinical animal models: an effect mediated by EGFR inhibition, p53 acetylation and oxidative stress (English)

1 reference

Europe PubMed Central

6 August 2017

1 reference

based on heuristic

inferred from title

author name string

Liqun Huang

1

1 reference

Europe PubMed Central

6 August 2017

Chi C Wong

2

1 reference

Europe PubMed Central

6 August 2017

Gerardo G Mackenzie

3

1 reference

Europe PubMed Central

6 August 2017

Yu Sun

4

1 reference

Europe PubMed Central

6 August 2017

Ka Wing Cheng

5

1 reference

Europe PubMed Central

6 August 2017

Kvetoslava Vrankova

6

1 reference

Europe PubMed Central

6 August 2017

Ninche Alston

7

1 reference

Europe PubMed Central

6 August 2017

Nengtai Ouyang

8

1 reference

Europe PubMed Central

6 August 2017

Basil Rigas

9

1 reference

Europe PubMed Central

6 August 2017

language of work or name

0 references

publication date

28 February 2014

1 reference

Europe PubMed Central

6 August 2017

1 reference

Europe PubMed Central

6 August 2017

14

1 reference

Europe PubMed Central

6 August 2017

141

1 reference

Europe PubMed Central

6 August 2017

https://scigraph.springernature.com/pub.10.1186/1471-2407-14-141

0 references

NF-κB non-cell-autonomously regulates cancer stem cell populations in the basal-like breast cancer subtype

1 reference

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9 July 2018

Comprehensive molecular portraits of human breast tumours

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941604

9 July 2018

The rebel angel: mutant p53 as the driving oncogene in breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941604

9 July 2018

Preclinical predictors of anticancer drug efficacy: critical assessment with emphasis on whether nanomolar potency should be required of candidate agents

1 reference

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9 July 2018

Dmp1 physically interacts with p53 and positively regulates p53's stability, nuclear localization, and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941604

9 July 2018

Cancer statistics, 2012

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941604

9 July 2018

Carboxylesterases 1 and 2 hydrolyze phospho-nonsteroidal anti-inflammatory drugs: relevance to their pharmacological activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941604

9 July 2018

Oxidative stress mediates through apoptosis the anticancer effect of phospho-nonsteroidal anti-inflammatory drugs: implications for the role of oxidative stress in the action of anticancer agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941604

9 July 2018

The novel phospho-non-steroidal anti-inflammatory drugs, OXT-328, MDC-22 and MDC-917, inhibit adjuvant-induced arthritis in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941604

9 July 2018

Critical roles of DMP1 in human epidermal growth factor receptor 2/neu-Arf-p53 signaling and breast cancer development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941604

9 July 2018

Phospho-sulindac (OXT-328), a novel sulindac derivative, is safe and effective in colon cancer prevention in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941604

9 July 2018

ADAM17 regulates epidermal growth factor receptor expression through the activation of Notch1 in non-small cell lung cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941604

9 July 2018

Posttranslational modification of p53: cooperative integrators of function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941604

9 July 2018

A novel sulindac derivative that does not inhibit cyclooxygenases but potently inhibits colon tumor cell growth and induces apoptosis with antitumor activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941604

9 July 2018

Blinded by the Light: The Growing Complexity of p53

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941604

9 July 2018

Aspirin and non-steroidal anti-inflammatory drugs for cancer prevention: an international consensus statement

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941604

9 July 2018

Phosphoaspirin (MDC-43), a novel benzyl ester of aspirin, inhibits the growth of human cancer cell lines more potently than aspirin: a redox-dependent effect

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941604

9 July 2018

The thioredoxin system mediates redox-induced cell death in human colon cancer cells: implications for the mechanism of action of anticancer agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941604

9 July 2018

The thioredoxin system: a key target in tumour and endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941604

9 July 2018

F2-isoprostanes in human health and diseases: from molecular mechanisms to clinical implications

1 reference

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9 July 2018

Acetylation is indispensable for p53 activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941604

9 July 2018

The ADAM17-amphiregulin-EGFR axis in mammary development and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941604

9 July 2018

Inhibition of SIRT1 catalytic activity increases p53 acetylation but does not alter cell survival following DNA damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941604

9 July 2018

NO-donating aspirin isomers downregulate peroxisome proliferator-activated receptor (PPAR)delta expression in APC(min/+) mice proportionally to their tumor inhibitory effect: Implications for the role of PPARdelta in carcinogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941604

9 July 2018

Nonsteroidal anti-inflammatory drug use and breast cancer risk by stage and hormone receptor status

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941604

9 July 2018

p53 mutation heterogeneity in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941604

9 July 2018

Immunohistochemical and clinical characterization of the basal-like subtype of invasive breast carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941604

9 July 2018

What now for aspirin and cancer prevention?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941604

9 July 2018

Targeting epidermal growth factor receptor--are we missing the mark?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941604

9 July 2018

A randomized trial of aspirin to prevent colorectal adenomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941604

9 July 2018

MDM2-HDAC1-mediated deacetylation of p53 is required for its degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941604

9 July 2018

The p53 pathway in breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941604

9 July 2018

One hundred years of aspirin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941604

9 July 2018

Thioredoxin regulates the DNA binding activity of NF-kappa B by reduction of a disulphide bond involving cysteine 62

1 reference

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Measurement of 8-iso-prostaglandin F2alpha in biological fluids as a measure of lipid peroxidation

1 reference

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27 September 2018

The novel phenylester anticancer compounds: Study of a derivative of aspirin (phoshoaspirin).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941604

27 September 2018

High thioredoxin expression is associated with resistance to docetaxel in primary breast cancer

1 reference

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Kit and FcepsilonRI mediate unique and convergent signals for release of inflammatory mediators from human mast cells

1 reference

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27 September 2018

Aspirin acetylates multiple cellular proteins in HCT-116 colon cancer cells: Identification of novel targets

1 reference

https://pubmed.ncbi.nlm.nih.gov/24575839

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidermal growth factor promotes MDA-MB-231 breast cancer cell migration through a phosphatidylinositol 3'-kinase and phospholipase C-dependent mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/24575839

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aspirin--the first hundred years

1 reference

https://pubmed.ncbi.nlm.nih.gov/24575839

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prognostic value of epidermal growth factor receptor (EGFR) and its relationship to the estrogen receptor status in 1029 patients with breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/24575839

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prognostic and predictive value of epidermal growth factor receptor in recurrent breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/24575839

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1186/1471-2407-14-141

1 reference

Europe PubMed Central

6 August 2017

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1 reference

Europe PubMed Central

6 August 2017

1 reference

Europe PubMed Central

6 August 2017

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