(Q35106239)

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Benzimidazoisoquinolines: a new class of rapidly metabolized aryl hydrocarbon receptor (AhR) ligands that induce AhR-dependent Tregs and prevent murine graft-versus-host disease

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scholarly article

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Europe PubMed Central

6 August 2017

Benzimidazoisoquinolines: a new class of rapidly metabolized aryl hydrocarbon receptor (AhR) ligands that induce AhR-dependent Tregs and prevent murine graft-versus-host disease (English)

1 reference

Europe PubMed Central

6 August 2017

6

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8 June 2020

Patrick L Iversen

8

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8 June 2020

author name string

Sumit Punj

1

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8 June 2020

Prasad Kopparapu

2

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8 June 2020

Hyo Sang Jang

3

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8 June 2020

Jessica L Phillips

4

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8 June 2020

Jamie Pennington

5

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8 June 2020

Edmond O'Donnell

7

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8 June 2020

Siva Kumar Kolluri

9

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8 June 2020

Nancy I Kerkvliet

10

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8 June 2020

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publication date

19 February 2014

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6 August 2017

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8 June 2020

9

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8 June 2020

e88726

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8 June 2020

2

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8 June 2020

copyright license

Creative Commons Attribution 4.0 International

19 February 2014

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April 2022 Public Data File from Crossref

copyright status

0 references

Activation of aryl hydrocarbon receptor (ahr) by tranilast, an anti-allergy drug, promotes miR-302 expression and cell reprogramming.

1 reference

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Coal tar induces AHR-dependent skin barrier repair in atopic dermatitis

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The aryl hydrocarbon receptor mediates leflunomide-induced growth inhibition of melanoma cells

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9 July 2018

The aryl hydrocarbon receptor regulates gut immunity through modulation of innate lymphoid cells

1 reference

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Deletion of the aryl hydrocarbon receptor enhances the inflammatory response to Leishmania major infection

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9 July 2018

Natural aryl hydrocarbon receptor ligands control organogenesis of intestinal lymphoid follicles

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9 July 2018

Exactly the same but different: promiscuity and diversity in the molecular mechanisms of action of the aryl hydrocarbon (dioxin) receptor

1 reference

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9 July 2018

Activation of the aryl hydrocarbon receptor suppresses sensitization in a mouse peanut allergy model.

1 reference

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9 July 2018

An endogenous aryl hydrocarbon receptor ligand acts on dendritic cells and T cells to suppress experimental autoimmune encephalomyelitis

1 reference

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9 July 2018

Aryl hydrocarbon receptor negatively regulates dendritic cell immunogenicity via a kynurenine-dependent mechanism

1 reference

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9 July 2018

The anti-inflammatory drug leflunomide is an agonist of the aryl hydrocarbon receptor

1 reference

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9 July 2018

An interaction between kynurenine and the aryl hydrocarbon receptor can generate regulatory T cells

1 reference

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9 July 2018

Inducible costimulator (ICOS) is a marker for highly suppressive antigen-specific T cells sharing features of TH17/TH1 and regulatory T cells.

1 reference

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9 July 2018

PKSolver: An add-in program for pharmacokinetic and pharmacodynamic data analysis in Microsoft Excel

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9 July 2018

Activation of aryl hydrocarbon receptor by TCDD prevents diabetes in NOD mice and increases Foxp3+ T cells in pancreatic lymph nodes

1 reference

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9 July 2018

Dioxin and immune regulation: emerging role of aryl hydrocarbon receptor in the generation of regulatory T cells

1 reference

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9 July 2018

No increased risk of cancer after coal tar treatment in patients with psoriasis or eczema.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929365

9 July 2018

Modeling of the aryl hydrocarbon receptor (AhR) ligand binding domain and its utility in virtual ligand screening to predict new AhR ligands

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929365

9 July 2018

Molecular mass ranges of coal tar pitch fractions by mass spectrometry and size-exclusion chromatography

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9 July 2018

Topical tar: back to the future

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3929365

9 July 2018

Activation of the aryl hydrocarbon receptor by the calcium/calmodulin-dependent protein kinase kinase inhibitor 7-oxo-7H-benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylic acid (STO-609).

1 reference

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9 July 2018

Functional characterization and gene expression analysis of CD4+ CD25+ regulatory T cells generated in mice treated with 2,3,7,8-tetrachlorodibenzo-p-dioxin

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Control of T(reg) and T(H)17 cell differentiation by the aryl hydrocarbon receptor

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9 July 2018

Dioxin-mediated up-regulation of aryl hydrocarbon receptor target genes is dependent on the calcium/calmodulin/CaMKIalpha pathway.

1 reference

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9 July 2018

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9 July 2018

Cutting edge: activation of the aryl hydrocarbon receptor by 2,3,7,8-tetrachlorodibenzo-p-dioxin generates a population of CD4+ CD25+ cells with characteristics of regulatory T cells

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T lymphocytes are direct, aryl hydrocarbon receptor (AhR)-dependent targets of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD): AhR expression in both CD4+ and CD8+ T cells is necessary for full suppression of a cytotoxic T lymphocyte response by TCDD.

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21 January 2018

2,3,7,8-Tetrachlorodibenzo-p-dioxin alters the differentiation of alloreactive CD8+ T cells toward a regulatory T cell phenotype by a mechanism that is dependent on aryl hydrocarbon receptor in CD4+ T cells

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21 January 2018

DNA adducts in skin biopsies and 1-hydroxypyrene in urine of psoriasis patients and healthy volunteers following treatment with coal tar.

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1 reference

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1 reference

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12 December 2020

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inferred from PubMed ID database lookup

Isoquinoline is a possible anti-psoriatic agent in coal tar

1 reference

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12 December 2020

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inferred from PubMed ID database lookup

Structural requirements for the induction of hepatic microsomal cytochrome P450 by imidazole- and pyridine-containing compounds in rats

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 reference

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12 December 2020

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inferred from PubMed ID database lookup

Immunology. Regulatory T cells get their chance to shine

1 reference

https://pubmed.ncbi.nlm.nih.gov/24586378

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0088726

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24586378%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

2014PLoSO...988726P

0 references

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24586378%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24586378%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

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