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Atomic level characterization of the nonproton ligand-sensing domain of ASIC3 channels.
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Europe PubMed Central
PMCID
3137073
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21586569%20AND%20SRC:MED&resulttype=core&format=json
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1 February 2020
title
Atomic level characterization of the nonproton ligand-sensing domain of ASIC3 channels
(English)
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PMCID
3137073
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1 February 2020
author
Huaiyu Yang
series ordinal
5
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3137073
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1 February 2020
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Ye Yu
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1
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3137073
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21586569%20AND%20SRC:MED&resulttype=core&format=json
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1 February 2020
Wei-Guang Li
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2
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1 February 2020
Zhi Chen
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3
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1 February 2020
Hui Cao
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4
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3137073
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21586569%20AND%20SRC:MED&resulttype=core&format=json
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1 February 2020
Hualiang Jiang
series ordinal
6
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3137073
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21586569%20AND%20SRC:MED&resulttype=core&format=json
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1 February 2020
Tian-Le Xu
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7
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3137073
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1 February 2020
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English
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publication date
17 May 2011
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3137073
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1 February 2020
published in
Journal of Biological Chemistry
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3137073
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1 February 2020
volume
286
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3137073
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1 February 2020
issue
28
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PMCID
3137073
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21586569%20AND%20SRC:MED&resulttype=core&format=json
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1 February 2020
page(s)
24996-25006
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retrieved
1 February 2020
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ASIC3 channels integrate agmatine and multiple inflammatory signals through the nonproton ligand sensing domain
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Atomic-level characterization of the structural dynamics of proteins
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A combined computational and functional approach identifies new residues involved in pH-dependent gating of ASIC1a.
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The contact region between three domains of the extracellular loop of ASIC1a is critical for channel function
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Pore architecture and ion sites in acid-sensing ion channels and P2X receptors
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Inherent dynamics of the acid-sensing ion channel 1 correlates with the gating mechanism
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Long-timescale molecular dynamics simulations of protein structure and function.
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Molecular dynamics simulations of membrane channels and transporters
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ASIC3, a sensor of acidic and primary inflammatory pain
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9 July 2018
Candidate amino acids involved in H+ gating of acid-sensing ion channel 1a.
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9 July 2018
Structure of acid-sensing ion channel 1 at 1.9 A resolution and low pH
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9 July 2018
A conformation change in the extracellular domain that accompanies desensitization of acid-sensing ion channel (ASIC) 3.
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Acid-sensing ion channels: advances, questions and therapeutic opportunities.
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Identification of the Ca2+ blocking site of acid-sensing ion channel (ASIC) 1: implications for channel gating
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Cationic DMPC/DMTAP lipid bilayers: molecular dynamics study.
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The ASICs: signaling molecules? Modulators?
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9 July 2018
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9 July 2018
Epithelial sodium channel/degenerin family of ion channels: a variety of functions for a shared structure.
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9 July 2018
Acid-sensing ion channel 3 matches the acid-gated current in cardiac ischemia-sensing neurons
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9 July 2018
Rational design and synthesis of a novel anti-leukemic agent targeting Bruton's tyrosine kinase (BTK), LFM-A13 [alpha-cyano-beta-hydroxy-beta-methyl-N-(2, 5-dibromophenyl)propenamide]
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9 July 2018
A proton-gated cation channel involved in acid-sensing
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9 July 2018
Calcium modulation in brain extracellular microenvironment demonstrated with ion-selective micropipette
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9 July 2018
A nonproton ligand sensor in the acid-sensing ion channel
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PubMed Central
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27 September 2018
Large-scale molecular dynamics simulations of self-assembling systems.
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27 September 2018
Permeating protons contribute to tachyphylaxis of the acid-sensing ion channel (ASIC) 1a.
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PubMed Central
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27 September 2018
Modulation of acid-sensing ion channel currents, acid-induced increase of intracellular Ca2+, and acidosis-mediated neuronal injury by intracellular pH.
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27 September 2018
A gating mutation in the internal pore of ASIC1a.
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27 September 2018
Trypsin cleaves acid-sensing ion channel 1a in a domain that is critical for channel gating
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27 September 2018
Characterization of acid-sensing ion channels in dorsal horn neurons of rat spinal cord.
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27 September 2018
The extracellular domain determines the kinetics of desensitization in acid-sensitive ion channel 1.
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27 September 2018
Combined three-dimensional quantitative structure-activity relationship analysis of cytochrome P450 2B6 substrates and protein homology modeling
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27 September 2018
Lactate enhances the acid-sensing Na+ channel on ischemia-sensing neurons
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27 September 2018
Proton sensitivity of ASIC1 appeared with the rise of fishes by changes of residues in the region that follows TM1 in the ectodomain of the channel
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16 November 2018
Pain due to tissue acidosis: a mechanism for inflammatory and ischemic myalgia?
1 reference
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PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21586569
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The pre-transmembrane 1 domain of acid-sensing ion channels participates in the ion pore
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21586569
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Structural biology: Unexpected opening
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PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21586569
retrieved
12 December 2020
based on heuristic
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Identifiers
DOI
10.1074/JBC.M111.239558
1 reference
stated in
Europe PubMed Central
PMCID
3137073
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21586569%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
PMCID
3137073
1 reference
stated in
Europe PubMed Central
PMCID
3137073
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21586569%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
PubMed ID
21586569
1 reference
stated in
Europe PubMed Central
PMCID
3137073
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21586569%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
ResearchGate publication ID
51140784
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