(Q35112954)

6 August 2017

title

Compound C stimulates heme oxygenase-1 gene expression via the Nrf2-ARE pathway to preserve human endothelial cell survival (English)

1 reference

6 August 2017

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Xiao-Ming Liu

1

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6 August 2017

Kelly J Peyton

2

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6 August 2017

Ahmad R Shebib

3

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6 August 2017

Hong Wang

4

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6 August 2017

William Durante

5

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6 August 2017

language of work or name

English

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publication date

24 May 2011

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6 August 2017

published in

Biochemical Pharmacology

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6 August 2017

volume

82

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6 August 2017

issue

4

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6 August 2017

page(s)

371-379

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Activation of AMPK stimulates heme oxygenase-1 gene expression and human endothelial cell survival

6 August 2017

cites work

1 reference

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9 July 2018

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Flow activation of AMP-activated protein kinase in vascular endothelium leads to Krüppel-like factor 2 expression

9 July 2018

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AMPK inhibitor Compound C stimulates ceramide production and promotes Bax redistribution and apoptosis in MCF7 breast carcinoma cells.

9 July 2018

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AMP-activated protein kinase-dependent and -independent mechanisms underlying in vitro antiglioma action of compound C.

9 July 2018

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Heme oxygenase-1, a critical arbitrator of cell death pathways in lung injury and disease

9 July 2018

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AMP-activated protein kinase functionally phosphorylates endothelial nitric oxide synthase Ser633

9 July 2018

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Suppression of the JNK pathway by induction of a metabolic stress response prevents vascular injury and dysfunction.

9 July 2018

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Compound C inhibits clonal expansion of preadipocytes by increasing p21 level irrespectively of AMPK inhibition

9 July 2018

1 reference

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Far infrared therapy inhibits vascular endothelial inflammation via the induction of heme oxygenase-1.

9 July 2018

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Apocynin is not an inhibitor of vascular NADPH oxidases but an antioxidant.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138903

Compound C inhibits hypoxic activation of HIF-1 independent of AMPK

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138903

Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism

9 July 2018

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The selectivity of protein kinase inhibitors: a further update

9 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138903

Nitric oxide stimulates heme oxygenase-1 gene transcription via the Nrf2/ARE complex to promote vascular smooth muscle cell survival

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138903

ATVB in focus: redox mechanisms in blood vessels

9 July 2018

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Heme oxygenase-1: a novel therapeutic target in oxidative tissue injuries

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138903

Distinct Cysteine Residues in Keap1 Are Required for Keap1-Dependent Ubiquitination of Nrf2 and for Stabilization of Nrf2 by Chemopreventive Agents and Oxidative Stress

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138903

Transcriptional Regulation of the Heme Oxygenase-1 Gene Via the Stress Response Element Pathway

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138903

Role of AMP-activated protein kinase in mechanism of metformin action

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138903

Mechanism of heme oxygenase-1 gene activation by cadmium in MCF-7 mammary epithelial cells. Role of p38 kinase and Nrf2 transcription factor

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138903

Uric acid oxidation by peroxynitrite: multiple reactions, free radical formation, and amplification of lipid oxidation

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138903

Oxidative stress causes enhanced endothelial cell injury in human heme oxygenase-1 deficiency

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138903

NO-mediated activation of heme oxygenase: endogenous cytoprotection against oxidative stress to endothelium

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138903

Multiple elements within the 5' distal enhancer of the mouse heme oxygenase-1 gene mediate induction by heavy metals.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138903

The enzymatic conversion of heme to bilirubin by microsomal heme oxygenase

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138903

Bilirubin is an antioxidant of possible physiological importance

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138903

Compound C sensitizes Caki renal cancer cells to TRAIL-induced apoptosis through reactive oxygen species-mediated down-regulation of c-FLIPL and Mcl-1.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138903

Mitochondrial respiratory chain and NAD(P)H oxidase are targets for the antiproliferative effect of carbon monoxide in human airway smooth muscle

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138903

Endoplasmic reticulum stress stimulates heme oxygenase-1 gene expression in vascular smooth muscle. Role in cell survival

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138903

"Lumen digestion" technique for isolation of aortic endothelial cells from heme oxygenase-1 knockout mice

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138903

Role of Nrf2 in the regulation of CD36 and stress protein expression in murine macrophages: activation by oxidatively modified LDL and 4-hydroxynonenal.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138903

Keap1 regulates both cytoplasmic-nuclear shuttling and degradation of Nrf2 in response to electrophiles

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138903

Laminar flow induction of antioxidant response element-mediated genes in endothelial cells. A novel anti-inflammatory mechanism

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138903

Carbon monoxide, oxidative stress, and mitochondrial permeability pore transition

27 September 2018

1 reference

12 December 2020

Physiologic cyclic stretch inhibits apoptosis in vascular endothelium

1 reference

12 December 2020

Characteristics of the inhibition of NADPH oxidase activation in neutrophils by apocynin, a methoxy-substituted catechol

1 reference

12 December 2020

Nitric oxide induces heme oxygenase-1 gene expression and carbon monoxide production in vascular smooth muscle cells

1 reference

12 December 2020

10.1016/J.BCP.2011.05.016

Identifiers

DOI

1 reference

6 August 2017

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6 August 2017

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