(Q35113299)

6 August 2017

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title

Cardiovascular drug therapy in the elderly: theoretical and practical considerations (English)

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6 August 2017

Bradley R Williams

1

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6 August 2017

Jiwon Kim

series ordinal

2

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6 August 2017

publication date

1 January 2003

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6 August 2017

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6 August 2017

volume

20

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6 August 2017

issue

6

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6 August 2017

page(s)

445-463

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https://scigraph.springernature.com/pub.10.2165/00002512-200320060-00004

6 August 2017

exact match

0 references

cites work

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Altered pharmacokinetics in the elderly.

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Guidelines for the diagnosis and treatment of chronic heart failure

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Alterations in leukocyte beta-receptor affinity with aging. A potential explanation for altered beta-adrenergic sensitivity in the elderly

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Clinical pharmacokinetics of angiotensin II (AT1) receptor blockers in hypertension

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Effect of Age and High Blood Pressure on Barorefiex Sensitivity in Man

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Digoxin or angiotensin converting enzyme inhibitors for congestive heart failure in geriatric patients. Which is the preferred treatment?

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Felodipine population dose-response and concentration-response relationships in patients with essential hypertension.

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Are β-Blockers Efficacious as First-line Therapy for Hypertension in the Elderly?

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Preoperative amiodarone as prophylaxis against atrial fibrillation after heart surgery

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Risk factors for intracranial hemorrhage in outpatients taking warfarin

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Impact of age on the cardiovascular response to dynamic upright exercise in healthy men and women.

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Central nervous system symptoms of elderly subjects using antihypertensive drugs

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12 December 2020

Effects of amlodipine, a long-acting dihydropyridine calcium antagonist in aging hypertension: pharmacodynamics in relation to disposition

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12 December 2020

Anticoagulants in older patients. A safety perspective

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12 December 2020

Aging and the anticoagulant response to warfarin therapy

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12 December 2020

Bisoprolol in the treatment of hypertension in the elderly

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12 December 2020

Experience of commencing Carvedilol in elderly patients with heart failure in a routine outpatient clinic

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12 December 2020

Prophylactic oral amiodarone compared with placebo for prevention of atrial fibrillation after coronary artery bypass surgery

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12 December 2020

Digoxin pharmacokinetics: multicompartmental analysis and its clinical implications

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12 December 2020

Efficacy of angiotensin-converting enzyme inhibition in reducing progression from asymptomatic left ventricular dysfunction to symptomatic heart failure in black and white patients

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12 December 2020

Factors affecting drug binding in plasma of elderly patients

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Factors affecting the maintenance dose of warfarin

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Age as a determinant of sensitivity to warfarin

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Aging, Total Body Potassium, Fat-free Mass, and Cell Mass in Males and Females Between Ages 18 and 85 Years

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Age and the renal blood supply: renal vascular responses to angiotensin converting enzyme inhibition in healthy humans

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Optimal dosage of ACE inhibitors in older patients

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12 December 2020

Orthostatic hypotension: therapeutic alternatives for geriatric patients.

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12 December 2020

Effect of age on plasma aldosterone response to exogenous angiotensin II in normotensive subjects

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12 December 2020

Losartan: a review of its use, with special focus on elderly patients

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12 December 2020

Antihypertensive therapy. Angiotensin-converting enzyme inhibitors, angiotensin II receptor antagonists, and calcium antagonists

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12 December 2020

Randomized trial of candesartan cilexetil in the treatment of patients with congestive heart failure and a history of intolerance to angiotensin-converting enzyme inhibitors

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

Beta-blocker use in elderly patients with coronary heart disease

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12 December 2020

Cardiovascular regulatory mechanisms in advanced age.

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12 December 2020

Gastric Emptying Rate in the Elderly: Implications for Drug Therapy

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12 December 2020

Verapamil pharmacodynamics and disposition in young and elderly hypertensive patients. Altered electrocardiographic and hypotensive responses

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12 December 2020

Effect of beta-blockade on mortality in patients with heart failure: a meta-analysis of randomized clinical trials

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12 December 2020

The role of the renin-angiotensin-aldosterone system in the management of heart failure

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12 December 2020

Lercanidipine: a review of its use in hypertension

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12 December 2020

Effect of age and gender on the activity of human hepatic CYP3A

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12 December 2020

The effect of carvedilol on morbidity and mortality in patients with chronic heart failure. U.S. Carvedilol Heart Failure Study Group

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12 December 2020

Digoxin in the elderly: Pharmacokinetic consequences of old age

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12 December 2020

Concurrent use of nonsteroidal anti-inflammatory drugs and oral anticoagulants places elderly persons at high risk for hemorrhagic peptic ulcer disease

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12 December 2020

Oral amiodarone for prevention of atrial fibrillation after open heart surgery, the Atrial Fibrillation Suppression Trial (AFIST): a randomised placebo-controlled trial

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12 December 2020

The sixth report of the Joint National Committee on prevention, detection, evaluation, and treatment of high blood pressure

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12 December 2020

Effects of Calcium-Channel Blockade in Older Patients with Diabetes and Systolic Hypertension

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12 December 2020

Responses to intravenous and oral diltiazem in elderly and younger patients with systemic hypertension

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12 December 2020

Adverse drug reactions in an elderly outpatient population

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12 December 2020

National patterns and predictors of beta-blocker use in patients with coronary artery disease

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12 December 2020

Comparative pharmacokinetic changes and drug therapy in an older population.

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12 December 2020

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12 December 2020

Effect of Digoxin on Ejection Fraction in Elderly Patients with Congestive Heart Failure

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12 December 2020

Optimal management of older patients with atrial fibrillation

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12 December 2020

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Single-drug therapy for hypertension in men. A comparison of six antihypertensive agents with placebo. The Department of Veterans Affairs Cooperative Study Group on Antihypertensive Agents.

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12 December 2020

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12 December 2020

Part I Digitalis glycosides: Mechanisms and manifestations of toxicity

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12 December 2020

beta-Blocker therapy in heart failure: scientific review

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12 December 2020

Identification and preliminary validation of predictors of major bleeding in hospitalized patients starting anticoagulant therapy

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12 December 2020

Aging Effects on the Vasculature in Health: Risk Factors for Cardiovascular Disease

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12 December 2020

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12 December 2020

Baroreceptor reflex in elderly essential hypertensives: effect of chronic inhibition of angiotensin converting enzyme

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12 December 2020

Long-term efficacy of amiodarone for the maintenance of normal sinus rhythm in patients with refractory atrial fibrillation or flutter.

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12 December 2020

Influence of physical activity on plasma digoxin in hospitalised patients

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12 December 2020

Side effects of long-term amiodarone therapy

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12 December 2020

Quinidine-induced changes in serum and skeletal muscle digoxin concentration; evidence of saturable binding of digoxin to skeletal muscle

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12 December 2020

Optimising ACE inhibitor therapy of congestive heart failure. Insights from pharmacodynamic studies

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12 December 2020

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12 December 2020

Long‐Term Survival and Use of Antihypertensive Medications in Older Persons

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12 December 2020

Effect of ageing upon warfarin dose requirements: a longitudinal study.

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12 December 2020

Effect of age on the renin-angiotensin-aldosterone system in normal subjects: simultaneous measurement of active and inactive renin, renin substrate, and aldosterone in plasma

1 reference

12 December 2020

Single- and multiple-dose nisoldipine kinetics and effects in the young, the middle-aged, and the elderly.

1 reference

12 December 2020

The role of angiotensin II receptor antagonists in hypertension management: focus on candesartan cilexetil

1 reference

12 December 2020

Effect of amiodarone on serum quinidine and procainamide levels

1 reference

12 December 2020

Relative efficacy and tolerability of lacidipine and amlodipine in patients with mild-to-moderate hypertension: a randomized double-blind study

1 reference

12 December 2020

Health outcomes associated with calcium antagonists compared with other first-line antihypertensive therapies: a meta-analysis of randomised controlled trials

1 reference

12 December 2020

Noncardiac side-effects of long-term oral amiodarone in the elderly

1 reference

12 December 2020

Pharmacokinetics in the elderly

1 reference

12 December 2020

How to use calcium antagonists in hypertension: putting the JNC-VI guidelines into practice. Joint National Committee for the Prevention, Detection, Evaluation and Treatment of High Blood Pressure

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12 December 2020

Gastric acidity in older adults

1 reference

12 December 2020

ACC/AHA Guidelines for the Evaluation and Management of Chronic Heart Failure in the Adult: Executive Summary A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee to Revise the 1995 Gu

1 reference

12 December 2020

The Cardiac Insufficiency Bisoprolol Study II (CIBIS-II): a randomised trial

1 reference

12 December 2020

Prediction of creatinine clearance from serum creatinine

1 reference

12 December 2020

Reduced serum albumin concentration in the elderly: a report from the Boston Collaborative Drug Surveillance Program

1 reference

12 December 2020

The potentiation of warfarin anticoagulation by amiodarone

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12 December 2020

Changes in drug metabolism with increasing age: 1. warfarin binding and plasma proteins

1 reference

12 December 2020

An overview of the pharmacokinetics and pharmacodynamics of amlodipine in elderly persons with systemic hypertension

1 reference

12 December 2020

Age differences in the water content of the body as related to basal oxygen consumption in males

1 reference

12 December 2020

Heart Failure Society of America (HFSA) practice guidelines. HFSA guidelines for management of patients with heart failure caused by left ventricular systolic dysfunction--pharmacological approaches

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12 December 2020

Blood pressure reduction and tolerability of felodipine ER in older and younger hypertensive patients. The Felodipine ER in the Elderly versus Young Working Group

1 reference

12 December 2020

Angiotensin II receptor antagonists. Potential in elderly patients with cardiovascular disease

1 reference

12 December 2020

Improvement in exercise tolerance and symptoms of congestive heart failure during treatment with candesartan cilexetil. Symptom, Tolerability, Response to Exercise Trial of Candesartan Cilexetil in Heart Failure (STRETCH) Investigators

1 reference

12 December 2020

1 reference

12 December 2020

Toxicity of high-dose flurazepam in the elderly

1 reference

12 December 2020

Aging and the nervous system

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12 December 2020

Population aging: a comparison among industrialized countries.

1 reference

12 December 2020

Determinants of angiotensin-converting enzyme inhibitor prescription in severe heart failure with left ventricular systolic dysfunction: the EPICAL study

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12 December 2020

Human alpha-1-glycoprotein and its interactions with drugs

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12 December 2020

Long-term results of amiodarone therapy in patients with recurrent sustained ventricular tachycardia or ventricular fibrillation

1 reference

12 December 2020

Blood pressure response to the first dose of angiotensin-converting enzyme inhibitors in congestive heart failure

1 reference

12 December 2020

Calcium antagonists in the elderly. A risk-benefit analysis

1 reference

12 December 2020

When, and when not, to use digoxin in the elderly

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12 December 2020

Effects of age and aerobic capacity on arterial stiffness in healthy adults

1 reference

12 December 2020

Effects of acute beta-adrenergic receptor blockade on age-associated changes in cardiovascular performance during dynamic exercise

1 reference

12 December 2020

Consensus recommendations for the management of chronic heart failure

1 reference

12 December 2020

Candesartan cilexetil. A review of its use in essential hypertension

1 reference

12 December 2020

The distribution and concentration of tritiated digoxin in human tissues

1 reference

12 December 2020

Management of acute myocardial infarction in the elderly

1 reference

12 December 2020

Pharmacokinetics and blood pressure effects of felodipine in elderly hypertensive patients. A comparison with young healthy subjects

1 reference

12 December 2020

Disposition of Antipyrine and Phenytoin Correlated with Age and Liver Volume in Man

1 reference

12 December 2020

Pharmacokinetics of candesartan after single and repeated doses of candesartan cilexetil in young and elderly healthy volunteers.

1 reference

12 December 2020

Understanding digoxin use in the elderly patient

1 reference

12 December 2020

Hemodynamic consequences of long-term beta-blocker therapy: a 5-year follow-up study of atenolol

1 reference

12 December 2020

A multicenter, randomized, double-blind study of the antihypertensive efficacy and tolerability of irbesartan in patients aged > or = 65 years with mild to moderate hypertension

1 reference

12 December 2020

Pharmacokinetics and pharmacodynamics in young normal and elderly hypertensive subjects: a study using sotalol as a model drug

1 reference

12 December 2020

Antihypertensive therapy in the aged patient. Clinical pharmacokinetic considerations

1 reference

12 December 2020

The Effect of Age on Creatinine Clearance in Men: A Cross-sectional and Longitudinal Study

1 reference

12 December 2020

Risk factors for the development of specific noncardiovascular adverse effects associated with amiodarone.

1 reference

12 December 2020

Correlation of estimated renal function parameters versus 24-hour creatinine clearance in ambulatory elderly

1 reference

12 December 2020

Echocardiographic assessment of a normal adult aging population

1 reference

12 December 2020

Gastrointestinal and liver function of old age

1 reference

12 December 2020

The importance of age as a predictor of atrial fibrillation and flutter after coronary artery bypass grafting.

1 reference

12 December 2020

ACC/AHA/ESC Guidelines for the Management of Patients With Atrial Fibrillation: Executive Summary A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the European Society of Cardiology Comm

1 reference

12 December 2020

The effects of irbesartan added to hydrochlorothiazide for the treatment of hypertension in patients non-responsive to hydrochlorothiazide alone

1 reference

12 December 2020

Decline in beta adrenergic receptor-mediated vascular relaxation with aging in man

1 reference

12 December 2020

Hepatic cytochrome P-4503A (CYP3A) activity in the elderly

1 reference

12 December 2020

The incidence, magnitude, and time course of the amiodarone-warfarin interaction

1 reference

12 December 2020

Therapy for acute myocardial infarction.

1 reference

12 December 2020

The Effects of Blood Pressure Reduction in Older Patients: An Overview of Five Randomized Controlled Trials in Elderly Hypertensives

1 reference

12 December 2020

Reduced β-adrenoceptor sensitivity in the elderly

1 reference

12 December 2020

Elimination of nadolol by patients with renal impairment

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12 December 2020

Deaths: final data for 1998.

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12 December 2020

Antithrombotic therapy to prevent stroke in patients with atrial fibrillation: a meta-analysis

1 reference

12 December 2020

Altered pharmacodynamics of cardiovascular drugs and their relation to altered pharmacokinetics in elderly patients

1 reference

12 December 2020

Amiodarone: clinical efficacy and toxicity in 96 patients with recurrent, drug-refractory arrhythmias

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12 December 2020

The effect of age on plasma levels of propranolol and practolol in man

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12 December 2020

Calcium antagonists in geriatric patients: diltiazem in elderly persons with hypertension

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12 December 2020

Pharmacokinetic aspects of some β-adrenoceptor blocking drugs

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12 December 2020

The effect of digoxin on mortality and morbidity in patients with heart failure

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12 December 2020

Digitalisation and digitalis detoxication in the elderly

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12 December 2020

Measured versus estimated creatinine clearance in a high-functioning elderly sample: MacArthur Foundation Study of Successful Aging.

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12 December 2020

Aging alters verapamil elimination and dynamics: single dose and steady-state responses.

1 reference

12 December 2020

Dangerous interaction between amiodarone and quinidine

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12 December 2020

Aging and drug disposition--pharmacodynamics

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12 December 2020

Digoxin Metabolism in the Elderly

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12 December 2020

A study of the efficacy and safety of irbesartan in combination with conventional therapy, including ACE inhibitors, in heart failure. Irbesartan Heart Failure Group

1 reference

12 December 2020

The effects of age and gender on the pharmacokinetics of irbesartan

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12 December 2020

10.2165/00002512-200320060-00004

Identifiers

DOI

1 reference

Dimensions Publication ID

6 August 2017

1022358038

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