(Q35117079)

6 August 2017

1 reference

title

The role of 5-HT on the cardiovascular and renal systems and the clinical potential of 5-HT modulation (English)

1 reference

6 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12720492

28 December 2023

1 reference

https://api.crossref.org/works/10.1517/13543784.12.5.805

28 December 2023

Sheila A. Doggrell

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12720492

28 December 2023

language of work or name

English

0 references

publication date

1 May 2003

1 reference

full work available at URL

6 August 2017

http://www.tandfonline.com/doi/pdf/10.1517/13543784.12.5.805

1 reference

https://api.crossref.org/works/10.1517/13543784.12.5.805

Expert Opinion on Investigational Drugs

28 December 2023

published in

1 reference

6 August 2017

volume

12

1 reference

6 August 2017

issue

5

1 reference

6 August 2017

page(s)

805-823

1 reference

Molecular, pharmacological and functional diversity of 5-HT receptors

6 August 2017

cites work

1 reference

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Serotonin 2B receptor is required for heart development

21 January 2018

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A novel role for serotonin in heart

21 January 2018

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A 5-hydroxytryptamine receptor in human atrium

21 January 2018

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Valvular heart disease associated with fenfluramine-phentermine

21 January 2018

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21 January 2018

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Evidence for possible involvement of 5-HT(2B) receptors in the cardiac valvulopathy associated with fenfluramine and other serotonergic medications

21 January 2018

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Modulation of contractions to ergonovine and methylergonovine by nitric oxide and thromboxane A2 in the human coronary artery.

21 January 2018

1 reference

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Serotonin-induced hypercontraction through 5-hydroxytryptamine 1B receptors in atherosclerotic rabbit coronary arteries

21 January 2018

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Serotonin-induced human coronary microvascular contraction during acute myocardial ischemia is blocked by COX-2 inhibition

21 January 2018

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Binding and functional affinity of sarpogrelate, its metabolite m-1 and ketanserin for human recombinant alpha-1-adrenoceptor subtypes

21 January 2018

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The role of serotonin in ischemic cellular damage and the infarct size-reducing effect of sarpogrelate, a 5-hydroxytryptamine-2 receptor blocker, in rabbit hearts

21 January 2018

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Effect of serotonin and thromboxane A2 on blood flow through moderately well developed coronary collateral vessels

21 January 2018

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Effectiveness of a novel serotonin blocker, sarpogrelate, for patients with angina pectoris

21 January 2018

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Sarpogrelate, a specific 5HT2-receptor antagonist, improves the coronary microcirculation in coronary artery disease

21 January 2018

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Sarpogrelate inhibits serotonin-induced proliferation of porcine coronary artery smooth muscle cells: implications for long-term graft patency

21 January 2018

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The effects of sarpogrelate on cardiomyocyte hypertrophy

21 January 2018

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Expression of serotonin receptor mRNAs in blood vessels

21 January 2018

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Primary pulmonary hypertension: Current therapy.

21 January 2018

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Inhaled diazeniumdiolates (NONOates) as selective pulmonary vasodilators

21 January 2018

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Evidence for 5-HT1-like receptor-mediated vasoconstriction in human pulmonary artery

21 January 2018

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5-hydroxytryptamine receptors mediating contraction in human small muscular pulmonary arteries: importance of the 5-HT1B receptor

21 January 2018

1 reference

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Further evidence that 5-HT-induced relaxation of pig pulmonary artery is mediated by endothelial 5-HT(2B) receptors

21 January 2018

1 reference

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5-HT1-receptor-mediated vasoconstriction in bovine isolated pulmonary arteries: influences of vascular endothelium and tone.

21 January 2018

1 reference

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Increased plasma serotonin in primary pulmonary hypertension

21 January 2018

1 reference

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Role of serotonin in the pathogenesis of acute and chronic pulmonary hypertension

21 January 2018

1 reference

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Appetite-suppressant drugs and the risk of primary pulmonary hypertension. International Primary Pulmonary Hypertension Study Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.5.805

The acute effects of dexfenfluramine on human and porcine pulmonary vascular tone and resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.5.805

Dexfenfluramine protects against pulmonary hypertension in rats

21 January 2018

1 reference

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Attenuated hypoxic pulmonary hypertension in mice lacking the 5-hydroxytryptamine transporter gene.

21 January 2018

1 reference

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Contribution of the 5-HT(1B) receptor to hypoxia-induced pulmonary hypertension: converging evidence using 5-HT(1B)-receptor knockout mice and the 5-HT(1B/1D)-receptor antagonist GR127935.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.5.805

Pulmonary responses to 5-hydroxytryptamine and endothelin-1 in a rabbit model of left ventricular dysfunction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.5.805

Pathophysiology and treatment of haemodynamic instability in acute pulmonary embolism: the pivotal role of pulmonary vasoconstriction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.5.805

Effect of a serotonin receptor antagonist on interleukin-6-induced pulmonary hypertension in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.5.805

Serotonin-induced contraction in mesenteric resistance arteries: signaling and changes in deoxycorticosterone acetate-salt hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.5.805

Upregulation of arterial serotonin 1B and 2B receptors in deoxycorticosterone acetate-salt hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.5.805

Responsiveness, affinity constants and receptor reserves for serotonin on aortae of aged normotensive and hypertensive rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.5.805

Vascular responses of isolated mesenteric resistance and basilar arteries from short- and long-term diabetic rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.5.805

Stimulation of aortic smooth muscle cell mitogenesis by serotonin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.5.805

Serotonin potentiates angiotensin II--induced vascular smooth muscle cell proliferation

21 January 2018

1 reference

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Synergistic effect of urotensin II with serotonin on vascular smooth muscle cell proliferation

21 January 2018

1 reference

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Lysophosphatidylcholine and reactive oxygen species mediate the synergistic effect of mildly oxidized LDL with serotonin on vascular smooth muscle cell proliferation

21 January 2018

1 reference

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Serotonin increases interleukin-6 synthesis in human vascular smooth muscle cells

21 January 2018

1 reference

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Central cardiovascular regulation and 5-hydroxytryptamine receptors

21 January 2018

1 reference

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Hypotension caused by extracorporeal circulation: serotonin from pump-activated platelets triggers nitric oxide release

21 January 2018

1 reference

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Pharmacotherapy of intermittent claudication

21 January 2018

1 reference

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Antithrombotic activity of AT-1015, a potent 5-HT(2A) receptor antagonist, in rat arterial thrombosis model and its effect on bleeding time

21 January 2018

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Serotonin receptor blockade improves distal perfusion after lower limb ischemia in the fatty Zucker rat.

21 January 2018

1 reference

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DOI, a 5-HT2 receptor agonist, induces renal vasodilation via nitric oxide in anesthetized dogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.5.805

Experimental diabetes induces hyperreactivity of rabbit renal artery to 5-hydroxytryptamine.

21 January 2018

1 reference

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Locally formed 5-hydroxytryptamine stimulates phosphate transport in cultured opossum kidney cells and in rat kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.5.805

The 5-HT2 receptor antagonist sarpogrelate reduces urinary and plasma levels of thromboxane A2 and urinary albumin excretion in non-insulin-dependent diabetes mellitus patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.5.805

Sarpogrelate hydrochloride, a serotonin2A receptor antagonist, reduces albuminuria in diabetic patients with early-stage diabetic nephropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.5.805

On the accurate determination of serotonin in human plasma

21 January 2018

1

1 reference

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Sensitization of Human Atrial 5-HT 4 Receptors by Chronic β-Blocker Treatment

28 December 2023

6

1 reference

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28 December 2023

Molecular Pharmacology

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Effect of 5-HT4 receptor stimulation on the pacemaker current If in human isolated atrial myocytes

28 December 2023

9

1 reference

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Anti-SSA/Ro52 autoantibodies blocking the cardiac 5-HT4 serotoninergic receptor could explain neonatal lupus congenital heart block

28 December 2023

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28 December 2023

Molecular Pharmacology

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Characterisation of 5-HT receptors in human coronary arteries by molecular and pharmacological techniques

28 December 2023

17

1 reference

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Effect of intracoronary serotonin on coronary vessels in patients with stable angina and patients with variant angina

28 December 2023

19

1 reference

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Divergent effects of serotonin on coronary-artery dimensions and blood flow in patients with coronary atherosclerosis and control patients

28 December 2023

20

1 reference

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Supersensitivity to serotonin- and histamine-induced arterial contraction following ovariectomy

28 December 2023

22

1 reference

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The influence of hyperthyroidism on vasoconstrictor and vasodilator responses in isolated coronary and renal resistance arteries

28 December 2023

23

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https://api.crossref.org/works/10.1517/13543784.12.5.805

Serotonin is associated with coronary artery disease and cardiac events

28 December 2023

25

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https://api.crossref.org/works/10.1517/13543784.12.5.805

Transcardiac serotonin concentration is increased in selected patients with limiting angina and complex coronary lesion morphology

28 December 2023

26

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Local effect of serotonin released during coronary angioplasty

28 December 2023

27

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Intracoronary serotonin release after high-pressure coronary stenting

28 December 2023

28

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Increased serotonin release across the coronary bed during a nonischemic interval in patients with vasospastic angina

28 December 2023

31

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5-HT1Dbeta receptor mediates the supersensitivity of isolated coronary artery to serotonin in variant angina

28 December 2023

32

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Sarpogrelate, a selective 5-HT2A serotonergic receptor antagonist, inhibits serotonin-induced coronary artery spasm in a porcine model

28 December 2023

33

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T102C polymorphism of the serotonin (5-HT) 2A receptor gene in patients with non-fatal acute myocardial infarction

28 December 2023

34

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Protective effect of serotonin (5-HT2) receptor antagonists in ischemic rat hearts

28 December 2023

35

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Protective effect of the serotonin receptor antagonist cinanserin in two canine models of pacing-induced myocardial ischemia

28 December 2023

36

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Effect of ketanserin on central haemodynamics and coronary circulation

28 December 2023

37

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Improvement of exercise capacity by sarpogrelate as a result of augmented collateral circulation in patients with effort angina

28 December 2023

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American Journal of Physiology

28 December 2023

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Dual effect of serotonin on growth of bovine pulmonary artery smooth muscle cells in culture

28 December 2023

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High Plasma Serotonin Levels in Primary Pulmonary Hypertension

28 December 2023

58

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Anorexic agents aminorex, fenfluramine, and dexfenfluramine inhibit potassium current in rat pulmonary vascular smooth muscle and cause pulmonary vasoconstriction

28 December 2023

66

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Dexfenfluramine as a mitogen signal via the formation of superoxide anion

28 December 2023

67

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Effect of dexfenfluramine treatment in rats exposed to acute and chronic hypoxia

28 December 2023

69

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Changes in systemic and regional haemodynamics during 5-HT7 receptor-mediated depressor responses in rats

28 December 2023

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Further pharmacological analysis of the orphan 5-HT receptors mediating feline vasodepressor responses: close resemblance to the 5-HT7, receptor

28 December 2023

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No evidence for functional involvement of 5-HT2B receptors in serotonin-induced vasodilatation in the human forearm

28 December 2023

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Serotonin and vasoconstrictor synergism

28 December 2023

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5-Hydroxytryptamine-induced potentiation of endothelin-1- and norepinephrine-induced contraction is mitogen-activated protein kinase pathway dependent

28 December 2023

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Effect of endothelium on diabetes-induced changes in constrictor responses mediated by 5-hydroxytryptamine in rat aorta

28 December 2023

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Effects of streptozotocin-induced diabetes on vascular reactivity in genetically hyperinsulinaemic obese Zucker rats

28 December 2023

89

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Effect of serotonin, thromboxane A2, and specific receptor antagonists on vascular smooth muscle cell proliferation

28 December 2023

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Synergy between thrombin and serotonin in inducing vascular smooth muscle cell proliferation

28 December 2023

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Hyperlipemic-very low density lipoprotein, intermediate density lipoprotein and low density lipoprotein act synergistically with serotonin on vascular smooth muscle cell proliferation

28 December 2023

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Mitogenic effect of serotonin on vascular endothelial cells

28 December 2023

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Effect of serotonin and thromboxane A2 on endothelial cell proliferation: effect of specific receptor antagonists

28 December 2023

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Serotonin (5-hydroxytryptamine, 5-HT) enhances migration of rat aortic smooth muscle cells through 5-HT2 receptors

28 December 2023

102

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Randomised controlled trial of ketanserin and aspirin in prevention of pre-eclampsia

28 December 2023

104

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The PACK trial: morbidity and mortality effects of ketanserin. Prevention of Atherosclerotic Complications

28 December 2023

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AT-1015, a novel serotonin (5-HT)2 receptor antagonist, blocks vascular and platelet 5-HT2A receptors and prevents the laurate-induced peripheral vascular lesion in rats

28 December 2023

108

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Changes in reactivity towards 5-hydroxytryptamine in the renal vasculature of the diabetic spontaneously hypertensive rat

28 December 2023

111

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Effects of vasodilatory beta-adrenoceptor antagonists on endothelium-derived nitric oxide release in rat kidney

28 December 2023

114

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Serotonin enhances the production of type IV collagen by human mesangial cells

28 December 2023

116

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Intraplatelet serotonin in patients with diabetes mellitus and peripheral vascular disease

28 December 2023

121

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Daily variations of platelet aggregation in relation to blood and plasma serotonin in diabetes

28 December 2023

122

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Therapeutic effect of sarpogrelate, a new 5-hydroxytryptamine receptor 2A antagonist, on diabetic nephropathy and neuropathy

28 December 2023

123

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In vitro studies with ICI 169,369, a chemically novel 5-HT antagonist

28 December 2023

126

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Syntheses and platelet aggregation inhibitory and antithrombotic properties of [2-[(omega-aminoalkoxy)phenyl]ethyl]benzenes

28 December 2023

129

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28 December 2023

Identifiers

1 reference

6 August 2017

1 reference