(Q35118477)

6 August 2017

1 reference

title

Epigenetics: the role of methylation in the mechanism of action of tumor suppressor genes (English)

1 reference

6 August 2017

Epigenetics: The Role of Methylation in the Mechanism of Action of Tumor Suppressor Genes (English)

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

29 December 2023

1 reference

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12724213

29 December 2023

tumor suppressor gene

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12724213

history and philosophy of science

29 December 2023

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

29 December 2023

author name string

Pawan K. Jain

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12724213

29 December 2023

language of work or name

English

0 references

publication date

1 March 2003

1 reference

full work available at URL

6 August 2017

https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1749-6632.2003.tb05963.x

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

https://nyaspubs.onlinelibrary.wiley.com/doi/pdf/10.1111/j.1749-6632.2003.tb05963.x

29 December 2023

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

Annals of the New York Academy of Sciences

29 December 2023

published in

1 reference

6 August 2017

983

1 reference

6 August 2017

71-83

1 reference

Oligodendroglial tumors frequently demonstrate hypermethylation of the CDKN2A (MTS1, p16INK4a), p14ARF, and CDKN2B (MTS2, p15INK4b) tumor suppressor genes.

6 August 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2003.TB05963.X

Hypermethylation of the DNA repair gene O(6)-methylguanine DNA methyltransferase and survival of patients with diffuse large B-cell lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2003.TB05963.X

DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development

21 January 2018

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/citations/10.1016/S0092-8674(00)81656-6

Cancer epigenetics takes center stage.

1

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

Cancer epigenetics comes of age

29 December 2023

2

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

Alterations in DNA Methylation: A Fundamental Aspect of Neoplasia

29 December 2023

6

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

Analysis of adenomatous polyposis coli promoter hypermethylation in human cancer

29 December 2023

7

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

Epigenetic gene silencing in cancer

29 December 2023

8

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

DNA hypermethylation in tumorigenesis: epigenetics joins genetics

29 December 2023

9

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

Promoter hypermethylation and BRCA1 inactivation in sporadic breast and ovarian tumors

29 December 2023

10

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

Epigenetic inactivation of LKB1 in primary tumors associated with the Peutz-Jeghers syndrome

29 December 2023

11

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

Amount and distribution of 5-methylcytosine in human DNA from different types of tissues of cells

29 December 2023

12

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

The heterogeneity of thymine methyl group origin in DNA pyrimidine isostichs of developing sea urchin embryos

29 December 2023

14

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

Cellular differentiation, cytidine analogs and DNA methylation

29 December 2023

15

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

Genomic imprinting in mammals.

29 December 2023

16

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

Role for DNA methylation in genomic imprinting

29 December 2023

17

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

Epigenetic programming of differential gene expression in development and evolution

29 December 2023

18

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

Multiple roles for DNA methylation in gametic imprinting

29 December 2023

19

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

Formation of methylation patterns in the mammalian genome

29 December 2023

21

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

Cloning, expression and chromosome locations of the human DNMT3 gene family

29 December 2023

22

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

A candidate mammalian DNA methyltransferase related to pmt1p of fission yeast

29 December 2023

23

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

Dnmt2 is not required for de novo and maintenance methylation of viral DNA in embryonic stem cells

29 December 2023

24

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

A mammalian protein with specific demethylase activity for mCpG DNA.

29 December 2023

25

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

How does DNA methylation repress transcription?

29 December 2023

26

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

CpG methylation of the cAMP-responsive enhancer/promoter sequence TGACGTCA abolishes specific factor binding as well as transcriptional activation

29 December 2023

27

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

Effects of DNA methylation on DNA-binding proteins and gene expression.

29 December 2023

28

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

CpG methylation within the 5' regulatory region of the BRCA1 gene is tumor specific and includes a putative CREB binding site

29 December 2023

29

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

A protein from human placental nuclei binds preferentially to 5-methylcytosine-rich DNA

29 December 2023

30

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

The repressor MDBP-2 is a member of the histone H1 family that binds preferentially in vitro and in vivo to methylated nonspecific DNA sequences

29 December 2023

31

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex

29 December 2023

32

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

Mi-2 complex couples DNA methylation to chromatin remodelling and histone deacetylation

29 December 2023

33

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

Identification of a mammalian protein that binds specifically to DNA containing methylated CpGs.

29 December 2023

34

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

DNA methylation inhibits transcription indirectly via a methyl-CpG binding protein

29 December 2023

35

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

Purification, sequence, and cellular localization of a novel chromosomal protein that binds to methylated DNA

29 December 2023

36

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin

29 December 2023

37

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

29 December 2023

38

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

Methylation-induced repression--belts, braces, and chromatin

29 December 2023

39

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

The "dark side" of chromatin remodeling: repressive effects on transcription

29 December 2023

40

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain

29 December 2023

41

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins

29 December 2023

42

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

Activation of mammalian DNA methyltransferase by cleavage of a Zn binding regulatory domain

29 December 2023

44

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

DNMT1 and DNMT3b cooperate to silence genes in human cancer cells

29 December 2023

46

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

Suppression of intestinal neoplasia by DNA hypomethylation.

29 December 2023

48

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription

29 December 2023

49

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer

29 December 2023

50

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma

29 December 2023

51

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

29 December 2023

Cancer cell cycles

52

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers

29 December 2023

53

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

A cell cycle regulator potentially involved in genesis of many tumor types

29 December 2023

54

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

p16 inactivation by methylation of the CDKN2A promoter occurs early during neoplastic progression in Barrett's esophagus

29 December 2023

56

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

Hypermethylation of the P15INK4b and P16INK4a in agnogenic myeloid metaplasia (AMM) and AMM in leukaemic transformation

29 December 2023

57

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

Expression of the Hypermethylated in Cancer gene (HIC-1) is associated with good outcome in human breast cancer

29 December 2023

58

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

Methylation of the HIC-1 candidate tumor suppressor gene in human breast cancer

29 December 2023

59

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

Variable promoter region CpG island methylation of the putative tumor suppressor gene Connexin 26 in breast cancer

29 December 2023

60

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

Phospholipase A(2) and cyclooxygenase gene expression in human preimplantation embryos

29 December 2023

62

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

Aberrant methylation and histone deacetylation of cyclooxygenase 2 in gastric cancer

29 December 2023

63

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

The E-cadherin gene is silenced by CpG methylation in human hepatocellular carcinomas

29 December 2023

66

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

Aberrant hypermethylation of the CHFR prophase checkpoint gene in human lung cancers

29 December 2023

67

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

The gene for a novel transmembrane protein containing epidermal growth factor and follistatin domains is frequently hypermethylated in human tumor cells

29 December 2023

68

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

HLTF gene silencing in human colon cancer

29 December 2023

69

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

Promoter hypermethylation of the EDNRB gene in nasopharyngeal carcinoma.

29 December 2023

70

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

Promoter hypermethylation of multiple genes in nasopharyngeal carcinoma

29 December 2023

71

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

RASSF1A promoter region CpG island hypermethylation in phaeochromocytomas and neuroblastoma tumours

29 December 2023

72

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

Inactivation of p57KIP2 by regional promoter hypermethylation and histone deacetylation in human tumors

29 December 2023

73

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

Inactivation of the apoptosis effector Apaf-1 in malignant melanoma

29 December 2023

75

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

Predicting lung cancer by detecting aberrant promoter methylation in sputum

29 December 2023

76

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

Methylation-specific oligonucleotide microarray: a new potential for high-throughput methylation analysis

29 December 2023

77

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer

29 December 2023

78

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

Hypomethylation of pericentromeric DNA in breast adenocarcinomas

29 December 2023

79

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

The 5-methylcytosine content of DNA from human tumors

29 December 2023

80

1 reference

https://api.crossref.org/works/10.1111/J.1749-6632.2003.TB05963.X

29 December 2023

Identifiers

1 reference

6 August 2017

1 reference