(Q35127370)

6 August 2017

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title

Pharmacoproteomics in drug development (English)

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6 August 2017

Frank A Witzmann

1

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PubMed ID

12746732

6 August 2017

Raymond A Grant

series ordinal

2

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6 August 2017

1 January 2003

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The Pharmacogenomics Journal

6 August 2017

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6 August 2017

3

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6 August 2017

69-76

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6 August 2017

2

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https://scigraph.springernature.com/pub.10.1038/sj.tpj.6500164

6 August 2017

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21 January 2018

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Integrated genomic and proteomic analyses of a systematically perturbed metabolic network

21 January 2018

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Two-dimensional gel electrophoresis: a powerful method to elucidate cellular responses to toxic compounds

21 January 2018

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Proteomics: applications and opportunities in preclinical drug development

21 January 2018

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Proteomic tools for biomedicine

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The role of proteomics in toxicology: identification of biomarkers of toxicity by protein expression analysis

21 January 2018

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Extraction of membrane proteins by differential solubilization for separation using two-dimensional gel electrophoresis.

21 January 2018

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A turning point in proteome analysis: sample prefractionation via multicompartment electrolyzers with isoelectric membranes

21 January 2018

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Peptide mass fingerprint sequence coverage from differently stained proteins on two-dimensional electrophoresis patterns by matrix assisted laser desorption/ionization-mass spectrometry (MALDI-MS).

21 January 2018

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Probability-based protein identification by searching sequence databases using mass spectrometry data

21 January 2018

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An approach to correlate tandem mass spectral data of peptides with amino acid sequences in a protein database

21 January 2018

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Linking genome and proteome by mass spectrometry: large-scale identification of yeast proteins from two dimensional gels

21 January 2018

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Tandem mass spectrometry methods for definitive protein identification in proteomics research

21 January 2018

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The characteristics of peptide collision-induced dissociation using a high-performance MALDI-TOF/TOF tandem mass spectrometer

21 January 2018

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Cyclosporine A-induced decrease in calbindin-D 28 kDa in rat kidney but not in cerebral cortex and cerebellum.

21 January 2018

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Cholesterol biosynthesis regulation and protein changes in rat liver following treatment with fluvastatin

21 January 2018

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Monitoring daunorubicin-induced alterations in protein expression in pancreas carcinoma cells by two-dimensional gel electrophoresis

21 January 2018

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Shotgun proteomics and biomarker discovery.

21 January 2018

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Proteomics of the eukaryotic transcription machinery: identification of proteins associated with components of yeast TFIID by multidimensional mass spectrometry

21 January 2018

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A proteomic analysis of human cilia: identification of novel components

21 January 2018

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Proteomic survey of metabolic pathways in rice

21 January 2018

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A proteomic view of the Plasmodium falciparum life cycle

21 January 2018

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The human plasma proteome: history, character, and diagnostic prospects

21 January 2018

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Quantitative analysis of complex protein mixtures using isotope-coded affinity tags

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Quantitative protein profiling using two-dimensional gel electrophoresis, isotope-coded affinity tag labeling, and mass spectrometry

21 January 2018

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Toward a high-throughput approach to quantitative proteomic analysis: expression-dependent protein identification by mass spectrometry

21 January 2018

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Quantitative proteome analysis by solid-phase isotope tagging and mass spectrometry

21 January 2018

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De novo peptide sequencing and quantitative profiling of complex protein mixtures using mass-coded abundance tagging

21 January 2018

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A method to identify and simultaneously determine the relative quantities of proteins isolated by gel electrophoresis

21 January 2018

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Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics

21 January 2018

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Application of surface-enhanced laser desorption/ionization technology to the detection and identification of urinary parvalbumin-alpha: a biomarker of compound-induced skeletal muscle toxicity in the rat.

21 January 2018

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Tagless extraction-retentate chromatography: a new global protein digestion strategy for monitoring differential protein expression

21 January 2018

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Use of proteomic patterns in serum to identify ovarian cancer

21 January 2018

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Chemical strategies for the global analysis of protein function

21 January 2018

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Direct visualization of serine hydrolase activities in complex proteomes using fluorescent active site-directed probes

21 January 2018

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Enzyme activity profiles of the secreted and membrane proteome that depict cancer cell invasiveness

21 January 2018

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Epoxide electrophiles as activity-dependent cysteine protease profiling and discovery tools

21 January 2018

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Development of photo-crosslinking reagents for protein kinase-substrate interactions

21 January 2018

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Biomedical applications of protein chips.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500164

Functional protein microarrays

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500164

Protein microarrays to detect protein-protein interactions using red and green fluorescent proteins.

21 January 2018

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Protein and antibody arrays and their medical applications.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500164

Selection of RNA aptamers that are specific and high-affinity ligands of the hepatitis C virus RNA-dependent RNA polymerase

21 January 2018

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Rapid determination of pharmacokinetic properties of new chemical entities: in vivo approaches

21 January 2018

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The cell as a collection of protein machines: preparing the next generation of molecular biologists

21 January 2018

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Direct analysis of protein complexes using mass spectrometry

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500164

Functional organization of the yeast proteome by systematic analysis of protein complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500164

Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500164

A novel genetic system to detect protein-protein interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500164

The yeast two-hybrid system and its pharmaceutical significance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500164

A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500164

A comprehensive two-hybrid analysis to explore the yeast protein interactome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500164

Comprehensive proteomic analysis of breast cancer cell membranes reveals unique proteins with potential roles in clinical cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500164

Functional discovery via a compendium of expression profiles

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500164

Assigning protein functions by comparative genome analysis: Protein phylogenetic profiles

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500164

Comparative assessment of large-scale data sets of protein-protein interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500164

Proteomics meets cell biology: the establishment of subcellular proteomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500164

Endoplasmic reticulum-mediated phagocytosis is a mechanism of entry into macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500164

Directed proteomic analysis of the human nucleolus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500164

Covalent protein modifications and gene expression changes in rodent liver following administration of methapyrilene: a study using two-dimensional electrophoresis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500164

7 January 2021

Cyclosporine A decreases the protein level of the calcium-binding protein calbindin-D 28kDa in rat kidney

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500164

7 January 2021

Two-dimensional electrophoresis of liver proteins: characterization of a drug-induced hepatomegaly in rats

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500164

7 January 2021

Proteomics to display lovastatin-induced protein and pathway regulation in rat liver

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500164

7 January 2021

Proteomic analysis of rat kidney cortex following treatment with gentamicin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500164

7 January 2021

Selective detection of membrane proteins without antibodies: a mass spectrometric version of the Western blot

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500164

7 January 2021

Protein microarray technology

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500164

7 January 2021

Automated acquisition of aptamer sequences

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500164

7 January 2021

Identifiers

DOI

10.1038/SJ.TPJ.6500164

1 reference

6 August 2017

1 reference

PubMed ID

12746732