(Q35135695)

6 August 2017

title

Calcineurin (CN) activation promotes apoptosis of glomerular podocytes both in vitro and in vivo (English)

1 reference

6 August 2017

1 reference

Liming Wang

1

1 reference

6 August 2017

Jae-Hyung Chang

2

1 reference

6 August 2017

Seung-Yeol Paik

3

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6 August 2017

Yuping Tang

4

1 reference

6 August 2017

William Eisner

5

1 reference

6 August 2017

Robert F Spurney

6

1 reference

6 August 2017

publication date

26 May 2011

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6 August 2017

published in

Molecular Endocrinology

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6 August 2017

volume

25

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6 August 2017

issue

8

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6 August 2017

page(s)

1376-1386

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Activation of NFAT signaling in podocytes causes glomerulosclerosis

6 August 2017

cites work

1 reference

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13 July 2018

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13 July 2018

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Angiotensin II infusion induces nephrin expression changes and podocyte apoptosis.

13 July 2018

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TRPC6 fulfills a calcineurin signaling circuit during pathologic cardiac remodeling

13 July 2018

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13 July 2018

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13 July 2018

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From the periphery of the glomerular capillary wall toward the center of disease: podocyte injury comes of age in diabetic nephropathy

13 July 2018

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13 July 2018

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Nuclear factor of activated T cells (NFAT) is involved in the depolarization-induced activation of growth hormone-releasing hormone gene transcription in vitro

13 July 2018

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Inhibition of human glioma cell growth by a PHS-2 inhibitor, NS398, and a prostaglandin E receptor subtype EP1-selective antagonist, SC51089.

13 July 2018

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Transcriptional regulation by calcium, calcineurin, and NFAT

13 July 2018

1 reference

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Prevention of diabetic nephropathy in rats by prostaglandin E receptor EP1-selective antagonist

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146249

Calcineurin as a multifunctional regulator

13 July 2018

1 reference

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Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy

13 July 2018

1 reference

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Apoptosis in podocytes induced by TGF-beta and Smad7

13 July 2018

1 reference

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The coxibs, selective inhibitors of cyclooxygenase-2.

13 July 2018

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TAT-mediated protein transduction into mammalian cells

13 July 2018

1 reference

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Myocyte-enriched calcineurin-interacting protein, MCIP1, inhibits cardiac hypertrophy in vivo

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146249

Podocyte number predicts long-term urinary albumin excretion in Pima Indians with Type II diabetes and microalbuminuria

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146249

Affinity-driven peptide selection of an NFAT inhibitor more selective than cyclosporin A.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146249

Transcription factors of the NFAT family: regulation and function

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146249

Direct demonstration of NFATp dephosphorylation and nuclear localization in activated HT-2 cells using a specific NFATp polyclonal antibody

13 July 2018

1 reference

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Fructosamine: structure, analysis, and clinical usefulness.

13 July 2018

1 reference

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FK-506- and CsA-sensitive activation of the interleukin-2 promoter by calcineurin

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146249

Mutated alpha subunit of the Gq protein induces malignant transformation in NIH 3T3 cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146249

Overexpression of cyclooxygenase-2 predisposes to podocyte injury.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146249

Targeting of calcineurin to an NFAT-like docking site is required for the calcium-dependent activation of the background K+ channel, TRESK.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146249

Glucose-induced reactive oxygen species cause apoptosis of podocytes and podocyte depletion at the onset of diabetic nephropathy

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146249

Role of podocytes for reversal of glomerulosclerosis and proteinuria in the aging kidney after endothelin inhibition.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146249

A new cell-permeable peptide allows successful allogeneic islet transplantation in mice

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146249

Involvement of calcineurin in transforming growth factor-beta-mediated regulation of extracellular matrix accumulation

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146249

Calcineurin is activated in diabetes and is required for glomerular hypertrophy and ECM accumulation

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146249

Podocyte number in normotensive type 1 diabetic patients with albuminuria

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146249

Cyclooxygenase-2 inhibitor blocks expression of mediators of renal injury in a model of diabetes and hypertension

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146249

Angiotensin II induces apoptosis in rat glomerular epithelial cells

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146249

The cyclosporin A-sensitive nuclear factor of activated T cells (NFAT) proteins are expressed in vascular smooth muscle cells. Differential localization of NFAT isoforms and induction of NFAT-mediated transcription by phospholipase C-coupled cell su

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146249

Effect of selective inhibition of thromboxane synthesis on renal function in diabetic nephropathy.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146249

Targeting the receptor-Gq interface to inhibit in vivo pressure overload myocardial hypertrophy

27 September 2018

1 reference

12 December 2020

Nuclear factor kappa B: important transcription factor and therapeutic target

1 reference

12 December 2020

NFATc1 autoregulation: a crucial step for cell-fate determination

1 reference

12 December 2020

Apoptosis in the kidneys of patients with type II diabetic nephropathy

1 reference

12 December 2020

Proteinuria and immunity--an overstated relationship?

1 reference

12 December 2020

An Essential Role of the Nuclear Factor of Activated T Cells in the Regulation of the Expression of the Cyclooxygenase-2 Gene in Human T Lymphocytes

1 reference

12 December 2020

Is podocyte injury relevant in diabetic nephropathy? Studies in patients with type 2 diabetes

1 reference

12 December 2020

Identifiers

DOI

10.1210/ME.2011-0029

1 reference

6 August 2017

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6 August 2017

1 reference