(Q35136365)

6 August 2017

title

Assessment of Mycobacterium tuberculosis pantothenate kinase vulnerability through target knockdown and mechanistically diverse inhibitors (English)

1 reference

Mycobacterium tuberculosis

6 August 2017

main subject

1 reference

B K Kishore Reddy

1

1 reference

6 August 2017

Sudhir Landge

2

1 reference

6 August 2017

Sudha Ravishankar

3

1 reference

6 August 2017

Vikas Patil

4

1 reference

6 August 2017

Vikas Shinde

5

1 reference

6 August 2017

Subramanyam Tantry

6

1 reference

6 August 2017

Manoj Kale

7

1 reference

6 August 2017

Anandkumar Raichurkar

8

1 reference

6 August 2017

Sreenivasaiah Menasinakai

9

1 reference

6 August 2017

Naina Vinay Mudugal

10

1 reference

6 August 2017

Anisha Ambady

11

1 reference

6 August 2017

Anirban Ghosh

12

1 reference

6 August 2017

Ragadeepthi Tunduguru

13

1 reference

6 August 2017

Parvinder Kaur

14

1 reference

6 August 2017

Ragini Singh

15

1 reference

6 August 2017

Naveen Kumar

16

1 reference

6 August 2017

Sowmya Bharath

17

1 reference

6 August 2017

Aishwarya Sundaram

18

1 reference

6 August 2017

Jyothi Bhat

19

1 reference

6 August 2017

Vasan K Sambandamurthy

20

1 reference

6 August 2017

Christofer Björkelid

21

1 reference

6 August 2017

T Alwyn Jones

22

1 reference

6 August 2017

Kaveri Das

23

1 reference

6 August 2017

Balachandra Bandodkar

24

1 reference

6 August 2017

Krishnan Malolanarasimhan

25

1 reference

6 August 2017

Kakoli Mukherjee

26

1 reference

6 August 2017

Vasanthi Ramachandran

27

1 reference

6 August 2017

language of work or name

English

0 references

publication date

31 March 2014

1 reference

Antimicrobial Agents and Chemotherapy

6 August 2017

published in

1 reference

6 August 2017

volume

58

1 reference

6 August 2017

issue

6

1 reference

6 August 2017

page(s)

3312-3326

1 reference

Structural and Biochemical Characterization of Compounds Inhibiting Mycobacterium tuberculosis Pantothenate Kinase

6 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068421

Genetic and chemical knockdown: a complementary strategy for evaluating an anti-infective target

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068421

Pathway-selective sensitization of Mycobacterium tuberculosis for target-based whole-cell screening

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068421

Scaling up interventions to achieve global tuberculosis control: progress and new developments

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068421

Drug-resistant tuberculosis--current dilemmas, unanswered questions, challenges, and priority needs

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068421

A kinetic platform for in silico modeling of the metabolic dynamics in Escherichia coli

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068421

Depletion of antibiotic targets has widely varying effects on growth

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068421

Essentiality and functional analysis of type I and type III pantothenate kinases of Mycobacterium tuberculosis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068421

Delineating bacteriostatic and bactericidal targets in mycobacteria using IPTG inducible antisense expression

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068421

Drivers of tuberculosis epidemics: the role of risk factors and social determinants

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068421

Coenzyme A biosynthesis: an antimicrobial drug target

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068421

A common mechanism of cellular death induced by bactericidal antibiotics

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068421

Coenzyme A: back in action

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068421

Long-term protection against tuberculosis following vaccination with a severely attenuated double lysine and pantothenate auxotroph of Mycobacterium tuberculosis.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068421

From genetic footprinting to antimicrobial drug targets: examples in cofactor biosynthetic pathways

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068421

Structural basis for the feedback regulation of Escherichia coli pantothenate kinase by coenzyme A

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068421

Microplate alamar blue assay versus BACTEC 460 system for high-throughput screening of compounds against Mycobacterium tuberculosis and Mycobacterium avium

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068421

Kinetics and regulation of pantothenate kinase from Escherichia coli

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068421

Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068421

Cloning, sequencing, and expression of the pantothenate kinase (coaA) gene of Escherichia coli

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068421

Screening, identification, and characterization of mechanistically diverse inhibitors of the Mycobacterium tuberculosis enzyme, pantothenate kinase (CoaA).

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068421

Pristinamycin-inducible gene regulation in mycobacteria.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068421

Acyl carrier protein is a cellular target for the antibacterial action of the pantothenamide class of pantothenate antimetabolites

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068421

Expression of the pyrG gene determines the pool sizes of CTP and dCTP in Lactococcus lactis

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068421

Quantification of intracellular metabolites in Escherichia coli K12 using liquid chromatographic-electrospray ionization tandem mass spectrometric techniques

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068421

Metabolic resistance: the protection of enzymes against drugs which are tight-binding inhibitors by the accumulation of substrate

27 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24687493

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Antimetabolite poisoning of cofactor biosynthesis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24687493

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Regulation of pantothenate kinase by coenzyme A and its thioesters

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24687493

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/AAC.00140-14

1 reference

6 August 2017

1 reference

6 August 2017

1 reference