(Q35139196)

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Fiber and penton base capsid modifications yield diminished adenovirus type 5 transduction and proinflammatory gene expression with retention of antigen-specific humoral immunity

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Fiber and penton base capsid modifications yield diminished adenovirus type 5 transduction and proinflammatory gene expression with retention of antigen-specific humoral immunity (English)

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

1 reference

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author name string

John W Schoggins

1

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Erik Falck-Pedersen

2

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

language of work or name

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publication date

30 August 2006

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Journal of Virology

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

80

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

21

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

10634-10644

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Akt/protein kinase B activation by adenovirus vectors contributes to NFkappaB-dependent CXCL10 expression

1 reference

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28 July 2018

Influence of fiber detargeting on adenovirus-mediated innate and adaptive immune activation

1 reference

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28 July 2018

Adenovirus Binding to Blood Factors Results in Liver Cell Infection and Hepatotoxicity

1 reference

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28 July 2018

The innate immune response to adenovirus vectors

1 reference

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28 July 2018

Evaluation of toxicity from high-dose systemic administration of recombinant adenovirus vector in vector-naive and pre-immunized mice.

1 reference

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28 July 2018

Immune responses to gene therapy vectors: influence on vector function and effector mechanisms

1 reference

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28 July 2018

Cytokine-mediated downregulation of coxsackievirus-adenovirus receptor in endothelial cells

1 reference

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28 July 2018

Adenovirus-induced maturation of dendritic cells through a PI3 kinase-mediated TNF-alpha induction pathway

1 reference

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28 July 2018

Modification to the capsid of the adenovirus vector that enhances dendritic cell infection and transgene-specific cellular immune responses

1 reference

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28 July 2018

Reduction of natural adenovirus tropism to mouse liver by fiber-shaft exchange in combination with both CAR- and alphav integrin-binding ablation

1 reference

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28 July 2018

The role of capsid-endothelial interactions in the innate immune response to adenovirus vectors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1641751

28 July 2018

Adenovirus serotype 5 fiber shaft influences in vivo gene transfer in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1641751

28 July 2018

Reduction of natural adenovirus tropism to the liver by both ablation of fiber-coxsackievirus and adenovirus receptor interaction and use of replaceable short fiber

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1641751

28 July 2018

Subgroup B and F fiber chimeras eliminate normal adenovirus type 5 vector transduction in vitro and in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1641751

28 July 2018

Adenovirus vector pseudotyping in fiber-expressing cell lines: improved transduction of Epstein-Barr virus-transformed B cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1641751

28 July 2018

Expression of coxsackie adenovirus receptor and alphav-integrin does not correlate with adenovector targeting in vivo indicating anatomical vector barriers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1641751

28 July 2018

Expression of the coxsackievirus and adenovirus receptor in cultured human umbilical vein endothelial cells: regulation in response to cell density

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1641751

28 July 2018

RGD inclusion in the hexon monomer provides adenovirus type 5-based vectors with a fiber knob-independent pathway for infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1641751

28 July 2018

Modification of the genetic program of human alveolar macrophages by adenovirus vectors in vitro is feasible but inefficient, limited in part by the low level of expression of the coxsackie/adenovirus receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1641751

28 July 2018

The coxsackievirus-adenovirus receptor protein can function as a cellular attachment protein for adenovirus serotypes from subgroups A, C, D, E, and F

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1641751

28 July 2018

Adenovirus type 5 fiber knob binds to MHC class I alpha2 domain at the surface of human epithelial and B lymphoblastoid cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1641751

28 July 2018

HCAR and MCAR: the human and mouse cellular receptors for subgroup C adenoviruses and group B coxsackieviruses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1641751

28 July 2018

Isolation of a common receptor for Coxsackie B viruses and adenoviruses 2 and 5

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1641751

28 July 2018

Adenovirus interaction with distinct integrins mediates separate events in cell entry and gene delivery to hematopoietic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1641751

28 July 2018

Adenovirus type 5 and 7 capsid chimera: fiber replacement alters receptor tropism without affecting primary immune neutralization epitopes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1641751

28 July 2018

Integrins alpha v beta 3 and alpha v beta 5 promote adenovirus internalization but not virus attachment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1641751

28 July 2018

Upregulation of integrins alpha v beta 3 and alpha v beta 5 on human monocytes and T lymphocytes facilitates adenovirus-mediated gene delivery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1641751

28 July 2018

Modified adenoviral vectors ablated for coxsackievirus-adenovirus receptor, alphav integrin, and heparan sulfate binding reduce in vivo tissue transduction and toxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1641751

27 September 2018

Rapid Kupffer cell death after intravenous injection of adenovirus vectors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1641751

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Evaluation of biodistribution and safety of adenovirus vectors containing group B fibers after intravenous injection into baboons.

1 reference

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A hemodynamic response to intravenous adenovirus vector particles is caused by systemic Kupffer cell-mediated activation of endothelial cells

1 reference

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27 September 2018

Receptor interactions involved in adenoviral-mediated gene delivery after systemic administration in non-human primates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1641751

27 September 2018

Simultaneous CAR- and alpha V integrin-binding ablation fails to reduce Ad5 liver tropism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1641751

27 September 2018

In vivo hepatic adenoviral gene delivery occurs independently of the coxsackievirus-adenovirus receptor

1 reference

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27 September 2018

CAR-binding ablation does not change biodistribution and toxicity of adenoviral vectors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1641751

27 September 2018

Heparan sulfate glycosaminoglycans are receptors sufficient to mediate the initial binding of adenovirus types 2 and 5.

1 reference

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27 September 2018

Acute cytokine response to systemic adenoviral vectors in mice is mediated by dendritic cells and macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1641751

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Structural analysis of the mechanism of adenovirus binding to its human cellular receptor, CAR

1 reference

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27 September 2018

An adenovirus vector with genetically modified fibers demonstrates expanded tropism via utilization of a coxsackievirus and adenovirus receptor-independent cell entry mechanism

1 reference

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1 reference

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Innate immune mechanisms dominate elimination of adenoviral vectors following in vivo administration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1641751

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Clearance of adenovirus-infected hepatocytes by MHC class I-restricted CD4+ CTLs in vivo

1 reference

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Long-term humoral and cellular immunity induced by a single immunization with replication-defective adenovirus recombinant vector

1 reference

https://pubmed.ncbi.nlm.nih.gov/16943295

12 December 2020

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Identifiers

10.1128/JVI.01359-06

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

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