(Q35140395)

6 August 2017

title

The antitumor effects of IFN-alpha are abrogated in a STAT1-deficient mouse (English)

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6 August 2017

Gregory B Lesinski

1

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6 August 2017

Mirela Anghelina

2

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6 August 2017

Jason Zimmerer

3

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6 August 2017

Timothy Bakalakos

4

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6 August 2017

Brian Badgwell

5

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6 August 2017

Robin Parihar

6

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6 August 2017

Yan Hu

7

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6 August 2017

Brian Becknell

8

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6 August 2017

Gerard Abood

9

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6 August 2017

Abhik Ray Chaudhury

10

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6 August 2017

Cynthia Magro

11

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6 August 2017

Joan Durbin

12

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6 August 2017

William E Carson

13

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6 August 2017

language of work or name

English

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publication date

1 July 2003

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Journal of Clinical Investigation

6 August 2017

published in

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6 August 2017

volume

112

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6 August 2017

issue

2

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6 August 2017

page(s)

170-180

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Interferon-alpha in tumor immunity and immunotherapy

6 August 2017

cites work

1 reference

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Interferons alpha and beta as immune regulators--a new look

13 July 2018

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Biologic consequences of Stat1-independent IFN signaling.

13 July 2018

1 reference

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Stat1-independent regulation of gene expression in response to IFN-gamma

13 July 2018

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RNA-dependent protein kinase PKR is required for activation of NF-kappa B by IFN-gamma in a STAT1-independent pathway.

13 July 2018

1 reference

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IFNalpha/beta promotes cell survival by activating NF-kappa B

13 July 2018

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Retroviral expression in embryonic stem cells and hematopoietic stem cells

13 July 2018

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High- and low-dose interferon alfa-2b in high-risk melanoma: first analysis of intergroup trial E1690/S9111/C9190.

13 July 2018

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Interferon-alpha-mediated down-regulation of angiogenesis-related genes and therapy of bladder cancer are dependent on optimization of biological dose and schedule.

13 July 2018

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Activation of the p38 mitogen-activated protein kinase by type I interferons

13 July 2018

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Activation of target-tissue immune-recognition molecules by double-stranded polynucleotides

13 July 2018

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Interferon-alpha-induced activation of signal transducer and activator of transcription proteins in malignant melanoma

13 July 2018

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A new mouse model of experimental melanoma for vaccine and lymphokine therapy

13 July 2018

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Demonstration of an interferon gamma-dependent tumor surveillance system in immunocompetent mice

13 July 2018

1 reference

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IFN-gamma priming up-regulates IFN-stimulated gene factor 3 (ISGF3) components, augmenting responsiveness of IFN-resistant melanoma cells to type I IFNs.

13 July 2018

1 reference

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Jaks and STATs: biological implications

13 July 2018

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Signal transduction in the interferon system.

13 July 2018

1 reference

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Targeted inhibition of interferon-gamma-dependent intercellular adhesion molecule-1 (ICAM-1) expression using dominant-negative Stat1.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=164283

Physical association between STAT1 and the interferon-inducible protein kinase PKR and implications for interferon and double-stranded RNA signaling pathways

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=164283

IFN regulatory factor-1 plays a central role in the regulation of the expression of class I and II MHC genes in vivo.

13 July 2018

1 reference

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Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease

13 July 2018

1 reference

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Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins

13 July 2018

1 reference

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Epidermal growth factor and lipopolysaccharide activate Stat3 transcription factor in mouse liver.

13 July 2018

1 reference

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Structure, chromosome localization, and regulation of expression of the interferon-regulated mouse Ifi54/Ifi56 gene family

13 July 2018

1 reference

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Production of high-titer helper-free retroviruses by transient transfection

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=164283

Potential uses of interferon alpha 2 as adjuvant therapy in cancer

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=164283

A severe combined immunodeficiency mutation in the mouse

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=164283

The complete nucleotide sequence of mouse 28S rRNA gene. Implications for the process of size increase of the large subunit rRNA In higher eukaryotes

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=164283

Immunological effects of recombinant interferon alfa-2a in patients with disseminated melanoma

13 July 2018

1 reference

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Interferon alfa-2a therapy for life-threatening hemangiomas of infancy

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=164283

Interferon alfa-2a for melanoma metastases.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=164283

Distinct requirements for IFNs and STAT1 in NK cell function

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=164283

L-selectin expression is low on CD34+ cells from patients with chronic myeloid leukemia and interferon-a up-regulates this expression

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=164283

Interferon-induced nuclear factors that bind a shared promoter element correlate with positive and negative transcriptional control

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=164283

Time-dependent suppression of melanoma metastases and natural killer cell activation by interferon

25 October 2018

1 reference

12 December 2020

Stat1 negatively regulates angiogenesis, tumorigenicity and metastasis of tumor cells

1 reference

12 December 2020

A fatal cytokine-induced systemic inflammatory response reveals a critical role for NK cells

1 reference

12 December 2020

A common nuclear signal transduction pathway activated by growth factor and cytokine receptors

1 reference

12 December 2020

Enhanced expression of melanoma-associated antigens and beta 2-microglobulin on cultured human melanoma cells by interferon

1 reference

12 December 2020

Role of natural killer and T-cells in interferon induced inhibition of spontaneous metastases of the B16F10L murine melanoma

1 reference

12 December 2020

Antitumor Functions of Natural Killer Cells and Control of Metastases

1 reference

12 December 2020

Effects of systemic interferon-alpha (IFN-alpha) on the antigenic phenotype of melanoma metastases. EORTC melanoma group cooperative study No. 18852

1 reference

12 December 2020

Enhanced in vivo sensitivity of in vitro interferon-treated B16 melanoma cells to CD8 cells and activated macrophages

1 reference

12 December 2020

Detection of intracellular phosphorylated STAT-1 by flow cytometry

1 reference

12 December 2020

Down-regulation of tumoricidal NK and NK T cell activities by MHC Kb molecules expressed on Th2-type gammadelta T and alphabeta T cells coinfiltrating in early B16 melanoma lesions

1 reference

12 December 2020

Malignant melanoma associates with Th1/Th2 imbalance that coincides with disease progression and immunotherapy response

1 reference

12 December 2020

Stem cell factor enhances interleukin-2-mediated expansion of murine natural killer cells in vivo

1 reference

12 December 2020

Serum imbalance of cytokines in melanoma patients

1 reference

12 December 2020

Defective Jak-STAT signal transduction pathway in melanoma cells resistant to growth inhibition by interferon-alpha

1 reference

12 December 2020

Systemic administration of human leukocyte interferon to melanoma patients. I. Effects on natural killer function and cell population

1 reference

12 December 2020

Immunohistochemical detection of the type I interferon receptor in human fetal, adult, and neoplastic tissues

1 reference

12 December 2020

Development of a new melanoma model in C57BL/6 mice

1 reference

12 December 2020

Early-appearing tumour-infiltrating natural killer cells play a crucial role in the generation of anti-tumour T lymphocytes

1 reference

12 December 2020

Two gamma-interferon-activation sites (GAS) on the promoter of the human intercellular adhesion molecule (ICAM-1) gene are required for induction of transcription by IFN-gamma

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI16603

1 reference

6 August 2017

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6 August 2017

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