(Q35147126)

6 August 2017

title

G-quadruplex structures and their interaction diversity with ligands (English)

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6 August 2017

Sulin Zhang

1

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6 August 2017

Yanling Wu

series ordinal

2

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6 August 2017

Wen Zhang

series ordinal

3

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6 August 2017

publication date

11 April 2014

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6 August 2017

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6 August 2017

volume

9

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6 August 2017

issue

5

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6 August 2017

page(s)

899-911

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Conformational changes of non-B DNA.

6 August 2017

cites work

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Human telomere, oncogenic promoter and 5'-UTR G-quadruplexes: diverse higher order DNA and RNA targets for cancer therapeutics

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Telomere maintenance as a target for anticancer drug discovery

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Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription

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Intracellular transcription of G-rich DNAs induces formation of G-loops, novel structures containing G4 DNA

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G-quadruplex structures are stable and detectable in human genomic DNA.

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Quantitative visualization of DNA G-quadruplex structures in human cells

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Visualization and selective chemical targeting of RNA G-quadruplex structures in the cytoplasm of human cells.

21 January 2018

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Human telomeric G-quadruplex: structures of DNA and RNA sequences

21 January 2018

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Quadruplex structures in nucleic acids

21 January 2018

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Combinatorially selected guanosine-quartet structure is a potent inhibitor of human immunodeficiency virus envelope-mediated cell fusion

21 January 2018

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Mechanism of inhibition of HIV-1 integrase by G-tetrad-forming oligonucleotides in Vitro

21 January 2018

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Unusual DNA structure of the diabetes susceptibility locus IDDM2 and its effect on transcription by the insulin promoter factor Pur-1/MAZ.

21 January 2018

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Formation of the G-quadruplex and i-motif structures in retinoblastoma susceptibility genes (Rb)

21 January 2018

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G-quadruplexes as therapeutic targets

21 January 2018

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Telomeres and telomerases as drug targets

21 January 2018

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Design and synthesis of an expanded porphyrin that has selectivity for the c-MYC G-quadruplex structure

21 January 2018

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A novel series of G-quadruplex ligands with selectivity for HIF-expressing osteosarcoma and renal cancer cell lines

21 January 2018

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Structure-based design and evaluation of naphthalene diimide G-quadruplex ligands as telomere targeting agents in pancreatic cancer cells

21 January 2018

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A model of smart G-quadruplex ligand

21 January 2018

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Quadruplex DNA: sequence, topology and structure

21 January 2018

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https://api.crossref.org/works/10.1002%2FCMDC.201300566

Crystal structure of parallel quadruplexes from human telomeric DNA

21 January 2018

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https://api.crossref.org/works/10.1002%2FCMDC.201300566

Solution structure of the human telomeric repeat d[AG3(T2AG3)3] G-tetraplex

21 January 2018

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https://api.crossref.org/works/10.1002%2FCMDC.201300566

Structure of a human telomeric DNA sequence stabilized by 8-bromoguanosine substitutions, as determined by NMR in a K+ solution

21 January 2018

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https://api.crossref.org/works/10.1002%2FCMDC.201300566

Formation of (3+1) G-quadruplexes with a long loop by human telomeric DNA spanning five or more repeats.

21 January 2018

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https://api.crossref.org/works/10.1002%2FCMDC.201300566

Propeller-type parallel-stranded G-quadruplexes in the human c-myc promoter

21 January 2018

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https://api.crossref.org/works/10.1002%2FCMDC.201300566

An intramolecular G-quadruplex structure with mixed parallel/antiparallel G-strands formed in the human BCL-2 promoter region in solution

21 January 2018

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https://api.crossref.org/works/10.1002%2FCMDC.201300566

Deconvoluting the structural and drug-recognition complexity of the G-quadruplex-forming region upstream of the bcl-2 P1 promoter

21 January 2018

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https://api.crossref.org/works/10.1002%2FCMDC.201300566

An interlocked dimeric parallel-stranded DNA quadruplex: a potent inhibitor of HIV-1 integrase

21 January 2018

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https://api.crossref.org/works/10.1002%2FCMDC.201300566

Engineering of interlocked DNA G-quadruplexes as a robust scaffold

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300566

Thrombin-binding DNA aptamer forms a unimolecular quadruplex structure in solution

21 January 2018

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https://api.crossref.org/works/10.1002%2FCMDC.201300566

The tertiary structure of a DNA aptamer which binds to and inhibits thrombin determines activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300566

A double chain reversal loop and two diagonal loops define the architecture of a unimolecular DNA quadruplex containing a pair of stacked G(syn)-G(syn)-G(anti)-G(anti) tetrads flanked by a G-(T-T) Triad and a T-T-T triple

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300566

Bulges in G-quadruplexes: broadening the definition of G-quadruplex-forming sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300566

The effect of sodium, potassium and ammonium ions on the conformation of the dimeric quadruplex formed by the Oxytricha nova telomere repeat oligonucleotide d(G(4)T(4)G(4))

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300566

Crystal structure of the potassium form of an Oxytricha nova G-quadruplex

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300566

Two-repeat Tetrahymena telomeric d(TGGGGTTGGGGT) Sequence interconverts between asymmetric dimeric G-quadruplexes in solution

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300566

Two-repeat human telomeric d(TAGGGTTAGGGT) sequence forms interconverting parallel and antiparallel G-quadruplexes in solution: distinct topologies, thermodynamic properties, and folding/unfolding kinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300566

(3 + 1) Assembly of three human telomeric repeats into an asymmetric dimeric G-quadruplex

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300566

G-quadruplex formation by human telomeric repeats-containing RNA in Na+ solution

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300566

Structure of propeller-type parallel-stranded RNA G-quadruplexes, formed by human telomeric RNA sequences in K+ solution

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300566

Structure of human telomeric RNA (TERRA): stacking of two G-quadruplex blocks in K(+) solution

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300566

Structural basis of telomeric RNA quadruplex--acridine ligand recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300566

Crystal structure of a promoter sequence in the B-raf gene reveals an intertwined dimer quadruplex

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300566

The crystal structure of a parallel-stranded guanine tetraplex at 0.95 A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300566

X-ray analysis of an RNA tetraplex (UGGGGU)4 with divalent Sr2+ ions at subatomic resolution (0.61 A)

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300566

Kinetics of double-chain reversals bridging contiguous quartets in tetramolecular quadruplexes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300566

Formation of an interlocked quadruplex dimer by d(GGGT).

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300566

Dynamics and thermodynamics of dimerization of parallel G-quadruplexed DNA formed from d(TTAGn) (n=3-5).

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300566

RNA G-quadruplexes: G-quadruplexes with "U" turns

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300566

Structure, function and targeting of human telomere RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300566

Engineering the quadruplex fold: nucleoside conformation determines both folding topology and molecularity in guanine quadruplexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300566

Methods for investigating G-quadruplex DNA/ligand interactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300566

Small-molecule interaction with a five-guanine-tract G-quadruplex structure from the human MYC promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300566

Evidence for the presence of a guanine quadruplex forming region within a polypurine tract of the hypoxia inducible factor 1alpha promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300566

Structural basis of DNA quadruplex recognition by an acridine drug

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300566

Structure of the first parallel DNA quadruplex-drug complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300566

A chiral wedge molecule inhibits telomerase activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300566

Isaindigotone derivatives: a new class of highly selective ligands for telomeric G-quadruplex DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300566

Effect of G-quadruplex polymorphism on the recognition of telomeric DNA by a metal complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300566

Small-molecule-induced DNA damage identifies alternative DNA structures in human genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300566

Evaluation of the interaction between long telomeric DNA and macrocyclic hexaoxazole (6OTD) dimer of a G-quadruplex ligand.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300566

Following G-quartet formation by UV-spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300566

Porphyrin binding to quadrupled T4G4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300566

Stabilizing parallel G-quadruplex DNA by a new class of ligands: two non-planar alkaloids through interaction in lateral grooves

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300566

Structural and thermodynamic studies of the interaction of distamycin A with the parallel quadruplex structure [d(TGGGGT)]4

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300566

Structure of a G-quadruplex-ligand complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300566

Selectivity in ligand recognition of G-quadruplex loops

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300566

Topology conservation and loop flexibility in quadruplex-drug recognition: crystal structures of inter- and intramolecular telomeric DNA quadruplex-drug complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300566

Ligand-driven G-quadruplex conformational switching by using an unusual mode of interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300566

Structure of long telomeric RNA transcripts: the G-rich RNA forms a compact repeating structure containing G-quartets

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300566

Chemistry in human telomere biology: structure, function and targeting of telomere DNA/RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300566

Tetraplex DNA and its interacting proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300566

Clostridium difficile TcdC protein binds four-stranded G-quadruplex structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300566

Cross-talk between prion protein and quadruplex-forming nucleic acids: a dynamic complex formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300566

Development of a fluorescent intercalator displacement assay (G4-FID) for establishing quadruplex-DNA affinity and selectivity of putative ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300566

The new models of the human telomere d[AGGG(TTAGGG)3] in K+ solution

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300566

7 January 2021

Topology variation and loop structural homology in crystal and simulated structures of a bimolecular DNA quadruplex

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300566

7 January 2021

Differential biophysical behavior of human telomeric RNA and DNA quadruplex

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300566

7 January 2021

A G-Quadruplex Ligand with 10000-Fold Selectivity over Duplex DNA

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300566

7 January 2021

Studies on the binding of 5-N-methylated quindoline derivative to human telomeric G-quadruplex

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300566

7 January 2021

Interaction of monomolecular G4-DNA nanowires with TMPyP: evidence for intercalation

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300566

7 January 2021

Identifiers

DOI

10.1002/CMDC.201300566

1 reference

6 August 2017

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